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The effect of glucagon on blood sugar and inorganic phosphorus levels in normothermic and hypothermic rats



The effect of glucagon on blood sugar and inorganic phosphorus levels in normothermic and hypothermic rats



Can J Physiol Pharmacol 43(4): 601-610



Injection of glucagon into normothermic rats led to hyperglycemia, and a significant fall in blood inorganic phosphorus levels. In hypothermic rats (25[degree]C) the injection of glucagon did not produce hyperglycemia but the reduction in blood inorganic phosphorus levels was still obtained. Following the administration of glucagon, an increase in the excretion of inorganic phosphorus in the urine was observed in both normothermic and hypothermic rats. The fall in blood inorganic phosphorus level was considered to be due, in part at least, to the effect of glucagon in increasing the excretion of phosphorus in the urine.

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Accession: 025750876

Download citation: RISBibTeXText

PMID: 14329345

DOI: 10.1139/y65-059


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