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The fate of certain organic acids and amides in the rabbit: 1. Benzoic and phenylacetic acids and their amides


The fate of certain organic acids and amides in the rabbit: 1. Benzoic and phenylacetic acids and their amides



Biochemical Journal 40(1): 134-139



ISSN/ISBN: 0264-6021

PMID: 16747961

The metabolism of benzoic and phenylacetic acids and their amides was studied by detn. of the increased excretion of ether-soluble acid and reducing substances. The % of dose of benzoic acid excreted (in 24 hrs.) conjugated with glycine was 77 and that with glucuronic acid was 11. Corresponding values for benzamide were 76 and 4; for phenylacetic acid, 53 and 5; and for phenylacetamide, 55 and 4. No increase in ethereal sulphate was observed.

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Accession: 025789786

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