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The riboflavin excreting mutant and the problem of variability in yeasts



The riboflavin excreting mutant and the problem of variability in yeasts



Jour Science and Indust Res india 9b(1): 4-11



Artificially produced top yeasts appear to be autotrophic and aerobic and excrete into the mash considerable amts. of riboflavin. Systematic observations of the changes in the sculpturing of the giant colonies of top yeasts extending over 2 yrs. indicate only a waxing and waning of the size of the rough rim during the different seasons when cultured at the room temp. The change parallels the predominance of the rough and smooth types of colonies in the 2-chromosome control. Since the top yeasts appear to be the results of a chromosomal translocation, the genic sequences should have been altered and as a result mutations at the loci governing the nature of sculpturing should produce phenotypic expressions entirely different from that observed in the control. Tetraploids are highly stable and industrial types should be polyploids.

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