Section 26
Chapter 25,942

The starvation ketosis of a monkey

Friedemann, T.E.

Proceedings Society Exp Biol and Med 24(3): 223-226


DOI: 10.3181/00379727-24-3306
Accession: 025941687

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In contrast to man, most animals develop only slight ketosis when starved. A fasting capuchin monkey weighing 1.3 kgm. developed ketosis comparable to that of man. Glucose and food promptly abolished the ketone body excretion. Of total acetone bodies, 9.2 m mols were excreted per 100 cal. heat output. Values for acetone excretion of fasting men, computed from the literature, are 8.0, 12.6, 11.6, 9.2, 11.0 m mols per 100 cal. heat production. The calorie output of the monkey was calculated from surface area estimated after death. A calculation of the expected acetone excretion on the basis of ketogenic versus antiketogenic factors (Shaffer) gave remarkable agreement with values found by analysis.

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