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The utilization of the a-carbon atom of glycine for the formation of acetic and aspartic acids

The utilization of the a-carbon atom of glycine for the formation of acetic and aspartic acids

Jour Biol Chem 178(1): 528-530

C14-labeled glycine fed with 1-alpha-amino-gamma-phenylbutyric acid to rats lead to urinary -excretion of acetyl-1-aminophenylbutyric acid. Both C atoms of the acetic acid were derived from the alpha-C of the glycine, as shown by activity counts. The activity of the alpha- and beta-C atoms of the aspartic acid formed was 2.5 times that of its carboxyl group.

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