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The Weight of the Normal Heart in Adult Males

The Weight of the Normal Heart in Adult Males

Yale Journal of Biology and Medicine 14(2): 209-223

A group of 187 [male][male] aged 20 yrs. and over with no cardiovascular disease at autopsy, dying either from trauma or from an acute disease requiring not more than 2 wks. of hospitalization, was studied to determine the influence of age, ht., and body wt. upon the wt. of the heart. The mean age for this group was 44.1 yrs. and the avg. heart wt. was 356 gs. A slight but significant positive correlation of .2670 was found between age and heart wt. It was not possible to exclude entirely the influence of hypertension as a factor accounting for this significant correlation. Body wt. and heart wt. were significantly correlated in a positive direction. This was independent of age. The multiple correlation between heart wt. and body wt. and age was .6287. This gave the lowest standard error of estimate of any of the correlation coefficients detd. The corresponding multiple regression equation was: Estimated Heart Wt. in Grams = Age + 3 (Body Wt. in kgs.) + 100. A diagnosis of cardiac hypertrophy was justified when the observed heart wt. exceeded by more than 77 gs. the estimated heart wt. derived by the use of this regression equation. The wt. in gs. per cm. of ht. divided by the heart wt. gave a range of from 0.8 to 2.0 with a mean of 1.17 and a standard deviation of 0.18. A similarly derived value, it was estimated, which was less than 0.8, could be interpreted as indicating cardiac hypertrophy.

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Accession: 025977104

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PMID: 21434009

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