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Therapeutic Applications of Organometallic Compounds

Therapeutic Applications of Organometallic Compounds

Annals of the New York Academy of Sciences 125: 189-197

ISSN/ISBN: 0077-8923

PMID: 14333049

DOI: 10.1111/j.1749-6632.1965.tb45390.x

The use of organometallic compounds in therapy has been reviewed from its inception in 1909 with the use of arsphenamine for the treatment of spirochetal and trypanosome infections, to their most recent applications in the diagnosis of malignancies and neutron capture therapy of gliomas. This evolution from their chronic use in the treatment of human infection to their infrequent use in diagnosis and irradiation therapy follows as a consequence of their inherent toxicity and of the development of more specific and less toxic non-metal containing drugs.

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Accession: 025980421

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