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Chapter 25,993

Tissue culture of bone marrow. II. Effect of steroid hormones on hematopoiesis in vitro

Reisner, E.H.

Blood 27(4): 460-469

1966


ISSN/ISBN: 0006-4971
PMID: 5931580
Accession: 025992368

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In cultures of normal human bone marrow in a medium of 20% horse serum and balanced salt solution, estrone stimulated granulopoiesis; testosterone inhibited fibroblast formation markedly and stimulated erythropoiesis; pred-nisolone inhibited fibroblast formation completely and allowed continued differentiation of all blood elements in smaller numbers.

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