Gastric acid secretion from the mucosa in response to synthetic gastrin and pentagastrin
Lear, J.; Kohatsu, S.; Oberhelman, H.A.
American Journal of Digestive Diseases 15(7): 627-631
ISSN/ISBN: 0002-9211 PMID: 4951400 DOI: 10.1007/bf02236020
The present study was undertaken to compare the gastric acid stimulatory properties of pentagastrin with those of human synthetic gastrin. Resting, isolated builfrog mucosae were exposed to pentagastrin and to human synthetic gastrin and mucosal acid secretory rates measured. Pentagastrin was found to be a more powerful stimulant of gastric acid secretion than human synthetic gastrin in this preparation.