+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Pituitary prolactin following hypothalamic de afferentation in male rats



Pituitary prolactin following hypothalamic de afferentation in male rats



General & Comparative Endocrinology 22(3): 360



The technique of Halasz et al. was used for extended frontal deafferentation (AC) and complete deafferentation (CC) of the mPdial hasal hypothalamus (MBH). Pituitary prolactin concentration (Pl) was determined 21 days after AC or CC by polyacrylamide gel disc electrophoresis by Davis et al., in normal male rats and in rats after long-term treatment with estradiol dipropionate (EP), 50 µg s.c. twice a week for 50 days. The results are as follows : pituitary Pl concentration in normal male rats was 4.4 µg/mg pituitary, and in AC rats it was 5.4 µg/mg pituitary; CC resultPd in an increase of Pl concentration to 8.0 µg/mg pituitary. Long-term treatment with EP caused an increase of Pl concentration to 10.5 JLg/mg pituitary, and after AC prolactin concentration was 12.3 µg/mg pituitary. These findings suggest nervous control for normal pituitary Pl level, via afferent inputs reaching the MBH from lateral or posterior direction.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 027156521

Download citation: RISBibTeXText


Related references

Age related release of prolactin by the pituitary and the pituitary hypothalamic complex in vitro an attempt to describe the development of the hypothalamic prolactin inhibiting and releasing activities in male rats. Journal of Endocrinology 115(3): 405-410, 1987

Prolactin message in brain and pituitary of adult male rats is identical: PCR cloning and sequencing of hypothalamic prolactin cDNA from intact and hypophysectomized adult male rats. Endocrinology 131(5): 2488-2490, 1992

Conversion of large prolactin to small prolactin by rat hypothalamic extract n 6 o 2 di butyryl cyclic amp and theophylline in pituitary mono layer cultures of male rats. Federation Proceedings 34(3): 342, 1975

Prolactin released in vitro from the pituitary of lactating, pregnant, and steroid-treated female or male rats stimulates prolactin secretion from pituitary lactotropes of male rats. Neuroendocrinology 91(1): 77-93, 2010

Pituitary prolactin hormone and hypothalamic prolactin inhibiting factor levels in rats bearing prolactin hormone secreting pituitary homo grafts abstract rat. Proc Int Union Physiol Sci 7(24): 316, 1968

Effects of a prolactin-secreting pituitary tumor on hypothalamic, gonadotropic and testicular function in male rats. Neuroendocrinology 30(1): 7, 1980

Influence of reactivity to novelty and anxiety on hypothalamic-pituitary-adrenal and prolactin responses to two different novel environments in adult male rats. Behavioural Brain Research 168(1): 13-22, 2006

The reduction of circulating growth hormone and prolactin in streptozocin-induced diabetic male rats is possibly caused by hypothalamic rather than pituitary changes. Journal of Endocrinology 145(1): 19-26, 1995

Age-associated decrease in serum prolactin level in male rats is unrelated to changes in anterior pituitary D-2 dopamine receptor and hypothalamic tyrosine hydroxylase or cyclo(His-Pro). Neuroendocrinology Letters 15(3): 203-211, 1993

Effect of pituitary extract on the gonadotropin and prolactin response to crude rat hypothalamic extract in vivo in male rats. Physiologist 13(3): 335, 1970

The effect of de afferentation or ablation of the medial basal hypothalamus on serum prolactin levels in male rats. Anatomical Record 181(2): 497, 1975

Increased hypothalamic catecholamine concentrations and decreased prolactin levels by fetal hypothalamic transplant in impotent aged male rats. Society for Neuroscience Abstracts 13(1): 569, 1987

Prolactin release, oestrogens and proliferation of prolactin-secreting cells in the anterior pituitary gland of adult male rats. Journal of Endocrinology 108(3): 399-403, 1986

Effects of pituitary tumor on hypothalamic catecholamines prolactin inhibiting activity pituitary prolactin and serum luteinizing hormone. Federation Proceedings: 556, 1978

Effects of pituitary homo grafts on host pituitary prolactin and hypothalamic prolactin inhibiting factor levels rat. Neuroendocrinology: 238-245, 1968