+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Assessment of thyroid function with hormone assays

Annales Chirurgiae et Gynaecologiae 72(3): 84-89
Assessment of thyroid function with hormone assays
Measurement of serum thyroid hormone and TSH levels provide diagnostic information in the majority of patients with thyroid dysfunction. The test strategy in hyperthyroidism differs from that in hypothyroidism. Serum T4 is a good test for hyperthyroidism in patients with normal thyroid hormone-binding protein levels. When binding proteins are abnormal serum free T4 is a much more accurate test for hyperthyroidism than serum T4. Serum T3 and the TSH response to TRH are useful tests for the early diagnosis of hyperthyroidism. Serum TSH is a very sensitive indicator of primary hypothyroidism rising already at the subclinical stage of the disease. Serum T4 and free T4, but not serum T3, are useful for the verification of clinical hypothyroidism. Determination of the TRH-stimulated TSH level is important for the differential diagnosis of pituitary and hypothalamic hypothyroidism. It is imperative to recognize that thyroid tests are often abnormal in various non-thyroidal diseases and that administration of drugs can affect these tests. Serum rT3 is of some value for the assessment of thyroid function in patients with non-thyroidal disease.

(PDF 0-2 workdays service: $29.90)

Accession: 027898127

PMID: 6414358

Related references

The uptake ratio between the thyroid and thymus as an index of thyroid function in assays of thyrotrophic hormone with P32 as indicator. Acta Endocrinologica 13(2): 145-156, 1953

American thyroid association assessment of current free thyroid hormone and thyrotropin measurements and guidelines for future clinical assays. Clinical Chemistry 37(11): 2002-2008, 1991

Free thyroid hormone assays and thyroid function. Annals of Clinical Biochemistry 23: 230-237, 1986

On the assessment of pituitary thyroid function in children plasma thyroid stimulating hormone levels with and without stimulation by synthetic thyrotropin releasing hormone. Acta Paediatrica Scandinavica 62(1): 94-95, 1973

Assessment of thyroid hormone assays. Journal of Clinical Pathology 29(12): 1054-1059, 1976

American Thyroid Association assessment of current free thyroid hormone and thyrotropin measurements and guidelines for future clinical assays. The Committee on Nomenclature of the American Thyroid Association. Clinical Chemistry 37(11): 2002-2008, 1991

Thyroid function tests in acutely ill patients. Comparison of analogue based free thyroid hormone assays with free thyroxine index. Pathology 18(1): 94-97, 1986

Evaluation of the thyroid function of healthy pregnant women by five different hormone assays. Die Pharmazie 65(6): 436-439, 2010

Serum thyroid-stimulating hormone measurement for assessment of thyroid function and disease. Endocrinology and Metabolism Clinics of North America 30(2): 245-64, Vii, 2001

Plasma thyroid stimulating hormone levels in the assessment of thyroid and pituitary function. Australian & New Zealand Journal Of Medicine: 424, 1973