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The transcription unit for poly inosinic acid poly cytidylic acid induced human fibroblast interferon messenger rna






Virology 102(1): 245-249

The transcription unit for poly inosinic acid poly cytidylic acid induced human fibroblast interferon messenger rna



Accession: 029430643



Related references

Sehgal, P.B.; Gupta, S.L., 1980: Regulation of the stability of poly inosinic acid poly cytidylic acid induced human fibroblast interferon messenger rna selective inactivation of interferon messenger rna and lack of involvement of 2' 5' oligo adenylic acid synthetase activation during the shutoff of interferon production. The inactivation of interferon mRNA during the shutoff phase of interferon production in poly(I).cntdot.poly(C)-induced human fibroblast (FS-4) cultures is selective. The shutoff of interferon production, which takes place from 3-8 h after the beg...

Sehgal P.B.; Sagar A.D., 1980: Heterogeneity of poly inosinic acid poly cytidylic acid induced human fibroblast interferon messenger rna species. Since it is generally considered that fibroblast (F) IFN (interferon) represents a single protein, current efforts to clone human F IFN mRNA sequences are based on the observation that F IFN mRNA sediments in sucrose gradients as a single RNA spec...

Sehgal P.B.; Tamm I., 1981: Synthesis structure and function of poly inosinic acid poly cytidylic acid induced human fibroblast interferon messenger rna. Vilcek, J , I Gresser And T C Merigan (Ed ) Annals Of The New York Academy Of Sciences, Vol 350 Regulatory Functions Of Interferons; Symposium, New York, N Y , Usa, Oct 23-26, 1979 Xiv+641p New York Academy Of Sciences: New York, N Y , Usa Illus P405-412, 1980

Nakamura O.; Machida H.; Matsutani M.; Takakura K., 1981: Interferon inducing activity of poly inosinic acid poly cytidylic acid and poly inosinic acid poly cytidylic acid poly l lysine carboxymethyl cellulose and its implication for the treatment of malignant brain tumors. Neurochirurgia (SUPPL): 365

Sehgal P.B.; Tamm I., 1979: 2 mechanisms contribute to the super induction of double stranded poly inosinic acid poly cytidylic acid induced human fibroblast interferon production. The cumulative interferon yield from cultures of poly(I).cntdot.poly(C)-induced human diploid fibroblasts (FS-4) in the first 24 h after induction is increased (superinduced) approximately 50-fold by appropriate treatment with 5,6-dichloro-1-.beta...

Brodskaya, L.M.; Vil'ner, L.M., 1976: Comparative anti viral and interferon inducing activity of synthetic poly ribo nucleotide complexes poly inosinic acid poly cytidylic acid and poly guanylic acid poly cytidylic acid in different cell systems. The antiviral and interferon-inducing activities of synthetic polyribonucleotide complexes poly(I).cntdot.poly(C) and poly(G).cntdot.poly(C) were studied in chick embryo, mouse embryo and rabbit kidney cell cultures. In chick embryo cell cultures...

Sehgal P.B., 1981: Regulation of the stability of human beta interferon messenger rna in poly inosinic acid poly cytidylic acid induced di ploid fibroblasts anchorage independence of the shutoff mechanism. Exposure of diploid human foreskin fibroblast (FS-4) monolayer cultures to poly(I) .cntdot. poly(C) leads to production of .beta. interferons within the 1st h; the rate of production peaks .apprx. 3 h after induction and is rapidly shut off by 6-8...

Olsen, G.A.; Kern, E.R.; Overall, J.C.J. ; Glasgow, L.A., 1978: Effect of treatment with exogenous interferon poly ribo inosinic acid poly ribo cytidylic acid or poly ribo inosinic acid poly ribo cytidylic acid poly l lysine complex on herpesvirus hominis infections in mice. The effect of treatment with exogenous interferon was compared with those of 2 interferon inducers, poly(I) .cntdot. poly(C) and poly(I) .cntdot. poly(C)-poly-L-lysine complex [poly(ICLC)], in 3 model Herpesvirus hominis type 2 infections of mice....

Kende M.; Glynn J.P., 1971: Modification of the response of autochthonous moloney sarcoma virus poly inosinic poly cytidylic acid induced tumors to poly inosinic poly cytidylic acid by deae dextran. Chemotherapy 16(5): 281-293

Stringfellow D.A.; Weed S.D., 1980: Interferon induction by and toxicity of poly ribo inosinic acid poly ribo cytidylic acid its mismatched uridylic acid containing analog and poly ribo inosinic acid poly ribo cytidylic acid l lysine complexed with carboxymethyl cellulose. The ability of polyriboinosionic acid [poly(rI)] .cntdot. polyribocytidylic acid [poly(rC)], mismatched analog poly(rI) .cntdot. poly[r(C12Uracil)n] and poly(rI) .cntdot. poly(rC) complexed with poly L-lysine and carboxymethylcellulose [poly(ICLC)...