+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

A new predictive PCR assay for detecting normal and malignant tissue thymidylate synthase gene expression in patients with 5-fluorouracil sensitive and resistant colorectal cancer



A new predictive PCR assay for detecting normal and malignant tissue thymidylate synthase gene expression in patients with 5-fluorouracil sensitive and resistant colorectal cancer



Proceedings of the American Association for Cancer Research Annual Meeting 34: 387




Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 029709404

Download citation: RISBibTeXText


Related references

Thymidylate synthase expression in normal colonic mucosa: a predictive marker of toxicity in colorectal cancer patients receiving 5-fluorouracil-based adjuvant chemotherapy. Oncology 67(2): 135-142, 2004

Polymorphisms in the enhancer region of the thymidylate synthase gene are associated with thymidylate synthase levels in normal tissues but not in malignant tissues of patients with colorectal cancer. Clinical Colorectal Cancer 8(3): 146-154, 2010

Predictive role of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer patients receiving adjuvant 5-fluorouracil. Oncology 70(5): 366-377, 2006

Thymidylate synthase expression in colorectal cancer: a prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy. Journal of Clinical Oncology 20(7): 1721-1728, 2002

Dynamic modulation of thymidylate synthase gene expression and fluorouracil sensitivity in human colorectal cancer cells. Plos One 10(4): E0123076, 2016

Predictive significance of thymidylate synthase and dihydropyrimidine dehydrogenase levels in patients with completely resected colorectal cancer receiving adjuvant 5-fluorouracil therapy. Journal of Clinical Oncology 23(16_Suppl): 3629-3629, 2016

Intratumoral thymidylate synthase expression and response to 5-fluorouracil-leucovorin in patients with colorectal cancer. Proceedings of the American Association for Cancer Research Annual Meeting 34: 353, 1993

Thymidylate synthase gene polymorphism and survival of colorectal cancer patients receiving adjuvant 5-fluorouracil. Genetic Testing and Molecular Biomarkers 17(11): 799-806, 2014

Thymidylate synthase and thymidine phosphorylase gene expression as predictive parameters for the efficacy of 5-fluorouracil-based adjuvant chemotherapy for gastric cancer. World Journal of Gastroenterology 13(37): 5030-5034, 2007

Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression after administration of 5-fluorouracil to patients with colorectal cancer. International Journal of Cancer 120(12): 2609-2612, 2007

Thymidylate synthase expression pattern is a prognostic factor in patients of colorectal cancer treated with 5-fluorouracil. International Journal of Oncology 25(4): 877-885, 2004

Prognostic and predictive value of the thymidylate synthase expression in patients with non-metastatic colorectal cancer. European Journal of Surgical Oncology 31(8): 863-868, 2005

Thymidylate synthase gene expression in normal and malignant colorectal tissues Relation to in vivo response and survival. Proceedings of the American Association for Cancer Research Annual Meeting 37: 201-202, 1996

Influence of thymidylate synthase gene polymorphisms on the survival of colorectal cancer patients receiving adjuvant 5-fluorouracil. Pharmacogenetics and Genomics 15(10): 723-730, 2005

Analysis of the thymidylate synthase gene structure in colorectal cancer patients and its possible relation with the 5-Fluorouracil drug response. Journal of Nucleic Acids 2010, 2010