A test to show the relative toxicity of a chemical to bacteria and to human leucocytes

Fleming, A.

International Archives of Allergy and Applied Immunology 5(2): 160-162


ISSN/ISBN: 0020-5915
PMID: 13183683
DOI: 10.1159/000228094
Accession: 029818863

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Defibrinated blood is mixed with about 2000 staphylococci/ml. and with corresponding dilution of the chemical to be tested. A drop is observed under the microscope between 2 slides. Most antiseptics in small concentrations were more toxic to leucocytes than to bacteria. Antibiotics and chemotherapeutics did not alter leucocytic function but decreased bacterial growth.