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Alpha -Tocopherol modulates human umbilical vein endothelial cell expression of Cu/Zn superoxide dismutase and catalase and lipid peroxidation


Alpha -Tocopherol modulates human umbilical vein endothelial cell expression of Cu/Zn superoxide dismutase and catalase and lipid peroxidation



Nutrition Research: 10, 671-680



DOI: 10.1016/j.nutres.2008.07.002

Recent studies suggest the potential of alpha -tocopherol as a gene regulator, possibly through peroxisome proliferator-activated receptor gamma (PPAR gamma ) activation due to the structural similarity of alpha -tocopherol to a PPAR gamma ligand, troglitazone. Other investigators have suggested that a link exists between induction of the antioxidant enzymes Cu/Zn superoxide dismutase (SOD) and catalase and PPAR gamma activation.

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