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Application of broncho-spirometry of the modified helium closed circuit method as a method for measuring intrapulmonary gas distribution



Application of broncho-spirometry of the modified helium closed circuit method as a method for measuring intrapulmonary gas distribution



Sci Rept Res Inst Tohoku Univ Seri C Med 10(4): 310-320



A new method of split intrapulmonary gas distribution measurement by the helium closed circuit method was described and this test was measured on 12 cases of normal subjects, 12 cases with unilateral pulmonary disease and 10 cases with bilateral pulmonary disease. No significant difference of gas distribution was found in the two lungs of normal subjects and the mean value of [DELTA] He and the helium equilibration time of the right and left lung were 0.37, 146 seconds and 0.32, 138 seconds respectively. In cases with a unilateral disease, marked gas distribution impairment was found in the diseased lung and the mean value of A He and the helium equilibration time of the normal and the diseased lungs were 0.35, 123 seconds and 0.08, 241 seconds respectively. In addition, the helium curve showed a particular shape in the diseased lung and was easily differentiated from the helium curve of the normal lung. In the case of bilateral diseases, the degree of gas distribution impairment generally corresponded with the extent of the diseases but did not correspond in the case of contralateral pleural thickening and in the case whose draining bronchus of the cavity was closed. In those cases the localization of gas distribution was diagnosed only by the split gas distribution test.

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Accession: 030150274

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