+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Breakthrough fungemia due to Hansenula anomala in a leukemia patient successfully treated with amphotericin B



Breakthrough fungemia due to Hansenula anomala in a leukemia patient successfully treated with amphotericin B



Journal of ChemoTherapy 8(1): 85-86



Intra-arterial (IA) and intravenous (IV) cisplatinum (CDP) were studied in a multiagent regimen of neoadjuvant chemotherapy for osteosarcoma of the extremities. Preoperatively two cycles of high-dose methotrexate (HDMTX) were administered, followed 5 days later by CDP and Adriamycin (ADM). MTX and ADM were administered IV, and CDP was delivered IA or IV. Postoperatively, good responders received 3 more cycles of the same drugs, while poor responders had a longer chemotherapy including ifosfamide. The rate of good histological response to chemotherapy was significantly higher in patients treated intraarterially (78% vs 46%: P < .004), while no significant differences in terms of disease-free survival were observed between patients who received CDP IA and patients who received CDP IV (55% vs 51%). In the IA group, however, there was only one local recurrence vs 5 in the IV group. The IA infusion of CDP is more active on the primary tumor than the IV infusion.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 030353999

Download citation: RISBibTeXText

PMID: 8835116

DOI: 10.1179/joc.1996.8.1.85


Related references

Breakthrough fungemia due to Hansenula anomala in a leukemic patient successfully treated with amphotericin B. ChemoTherapy 42(2): 157-158, 1996

Breakthrough fungemia caused by Candida stellatoidea in a patient with lymphoma associated with shock, successfully treated with amphotericin B lipid complex. Infection 23(4): 246-247, 1995

Hansenula anomala fungemia in a patient with acute myelocytic leukemia. Japanese Journal of Medical Mycology 34(4): 451-457, 1993

Breakthrough Candida dubliniensis fungemia in an acute myeloid leukemia patient during voriconazole therapy successfully treated with caspofungin. Journal of ChemoTherapy 21(1): 105-107, 2009

Hansenula anomala fungemia in a patient undergoing IVH-treatment with ascending colon carcinoma. Kansenshogaku Zasshi. Journal of the Japanese Association for Infectious Diseases 70(2): 198-205, 1996

Hansenula anomala Fungemia. Infectious Disease in Clinical Practice 19(3): 167-170, 2011

Hansenula anomala fungemia. Reviews of Infectious Diseases 10(6): 1182-1186, 1988

Fungemia by Hansenula anomala. Revista Argentina de Microbiologia 35(1): 54-56, Enero-Marzo, 2003

Fungemia due to Hansenula anomala. New York State Journal of Medicine 86(10): 541-542, 1986

Aureobasidium mansoni meningitis in a leukemia patient successfully treated with amphotericin B. ChemoTherapy 40(1): 70-71, 1994

Catheter-related fungemia by Hansenula anomala. Archives of Internal Medicine 149(3): 709, 713-709, 713, 1989

Nosocomial Aureobasidium mansoni meningitis in patient with leukemia successfully treated with amphotericin B. Abstracts of the General Meeting of the American Society for Microbiology 93: 535, 1993

Monilia albicans fungemia following multiple pelvic and abdominal procedures successfully treated with amphotericin B. American Journal of Surgery 100(3): 470-474, 1960

Fungemia caused by Hansenula anomala: successful treatment with fluconazole. Internal Medicine 31(5): 622-624, 1992

Neonatal fungemia caused by Hansenula anomala: a case report. Journal of Microbiology Immunology and Infection 33(4): 267-270, 2000