Comparison of three commercial immunoassays for detection of herpes simplex virus type 2 antibodies in commercial sex workers in Yunnan Province, China
Ngo, T.D.; Laeyendecker, O.; Morrow, R.A.; Lai, S.; Quinn, T.C.
Clinical and Vaccine Immunology Cvi 15(8): 1301-1303
ISSN/ISBN: 1556-679X PMID: 18508932 DOI: 10.1128/cvi.00006-08
Five hundred commercial sex workers in China were tested for herpes simplex virus type 2 by three immunoassays and Western blotting. Sensitivities for the Focus, Kalon, and Biokit assays were 86.7%, 82.3%, and 34.9%, respectively, and specificities were 91.8%, 94.2%, and 60.1%, respectively. The Focus assay performed optimally at an index of 1.5 (95.2% sensitivity and 93.4% specificity), and the Kalon assay performed optimally at an index of 1.2 (93.3% sensitivity and 95.2% specificity).