EurekaMag.com logo
+ Site Statistics
References:
53,623,987
Abstracts:
29,492,080
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Human immunosuppression induced by sea nettle (Chrysaora quinquecirrha) venom



Human immunosuppression induced by sea nettle (Chrysaora quinquecirrha) venom



Toxicon 29(3): 386-390



Large intradermal injections of crude sea nettle (Chrysaora quinquecirrha) venom in normal saline produced immunosuppression in a healthy human adult male. This response persisted several days and was homologous against that coelenterate antigen but also heterologous against antigens contained within vaccinia and herpes simplex viruses and tetanus bacillus. This down-regulation of immunity was probably mediated by cells with functional properties of suppressor cells and could be reversed by indomethacin suggesting a role for prostaglandins. This result suggests the possibility that naturally occurring environmental agents, other than sunlight, may influence the human immune response.

(PDF same-day service: $19.90)

Accession: 031737922

Download citation: RISBibTeXText

PMID: 1675499

DOI: 10.1016/0041-0101(91)90294-2



Related references

Sea nettle (Chrysaora quinquecirrha) nematocyst venom hemagglutinins. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology 74(1): 225-228, 1983

Effect of sea nettle (Chrysaora quinquecirrha) venom on isolated rat aorta. Toxicon 26(12): 1209-1212, 1988

Characterization of chrysaora quinquecirrha sea nettle nematocyst venom collagenase. Comparative Biochemistry & Physiology B 69(3): 529-534, 1981

Immunosorbent chromatography of sea nettle (Chrysaora quinquecirrha) venom and characterization of toxins. Toxicon 21(3): 385-391, 1983

Sea nettle (Chrysaora quinquecirrha) nematocyst venom: mechanism of action on muscle. Toxicon 21(1): 81-95, 1983

Partial purification and characterization of the alkaline protease of sea nettle chrysaora quinquecirrha nematocyst venom. Comparative Biochemistry & Physiology C Comparative Pharmacology 74(2): 361-364, 1983

Toxicity of sea nettle (Chrysaora quinquecirrha) fishing tentacle nematocyst venom in cultured rat hepatocytes. Toxicon 34(7): 771-778, 1996

Partial purification and characterization of the acid protease of sea nettle (Chrysaora quinquecirrha) nematocyst venom. Comparative Biochemistry and Physiology. B, Comparative Biochemistry 72(1): 93-97, 1982

Production of a mono clonal antibody against the sea nettle chrysaora quinquecirrha venom mouse lethal factor. Proceedings of the Society for Experimental Biology & Medicine 167(3): 374-377, 1981

Enzyme linked immuno sorbent assay to detect anti sea nettle chrysaora quinquecirrha venom antibodies. Experientia (Basel) 37(9): 1005-1007, 1981

Antitumor and antioxidant role of Chrysaora quinquecirrha (sea nettle) nematocyst venom peptide against Ehrlich ascites carcinoma in Swiss Albino mice. Molecular and Cellular Biochemistry 338(1-2): 69-76, 2010

Two new actions of sea nettle (Chrysaora quinquecirrha) nematocyst venom: studies on the mechanism of actions on complement activation and on the central nervous system. Toxicon 44(8): 895-899, 2004

Laboratory maintenance of the sea nettle chrysaora quinquecirrha agassiz. Journal of Aquariculture & Aquatic Sciences 5(2): 26-27, 1988