Inhaled nitric oxide and extracorporeal membrane oxygenation in persistent pulmonary hypertension of the newborn
Takata, M.; Miyasaka, K.; Sakai, H.; Fujiwara, H.; Ito, Y.; Kawano, T.
Acta Paediatrica Japonica Overseas Edition 37(2): 171-173
Persistent pulmonary hypertension of the newborn (PPHN) may occasionally require an invasive treatment with extracorporeal membrane oxygenation (ECMO). Inhaled nitric oxide (NO) has recently been introduced as a selective pulmonary vasodilator for treatment of PPHN. We describe a case of PPHN in which neither inhaled NO nor ECMO was effective in reversing pulmonary hypertension. The clinical course of the patient suggested a potential role of NO inhalation in predicting the outcome of ECMO treatment for PPHN.