+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

New approaches to the diagnosis, prevention, and treatment of cytomegalovirus infection after transplantation



New approaches to the diagnosis, prevention, and treatment of cytomegalovirus infection after transplantation



American Journal of Surgery 161(2): 250-255



Infection occurring after solid organ transplantation continues to exert a considerable detrimental effect upon patient and allograft survival. While the search for better targeted immunosuppressive regimens continues, we must seek to improve our ability to both diagnose and treat those infections that do occur after transplantation. Viral infections in general, and cytomegalovirus (CMV) infections in particular, represent an area in which substantial progress is being made. Improvement in diagnostic modalities has allowed more rapid and precise identification of CMV infection and disease, and the use of antiviral agents that possess activity against CMV has allowed both prophylaxis and treatment of this frequently life-threatening disease. The prophylactic use of presently available agents in combination and the development of less toxic, more potent anti-CMV agents should serve to further lessen the impact of CMV disease upon the field of solid organ transplantation.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 032524252

Download citation: RISBibTeXText

PMID: 1846724

DOI: 10.1016/0002-9610(91)91140-e


Related references

Current approaches to the prevention and treatment of cytomegalovirus disease after bone marrow transplantation: an overview. Seminars in Hematology 27(2 Suppl 1): 1-4; Discussion 28-9, 1990

Prevention and treatment of cytomegalovirus infection after marrow transplantation. Bone Marrow Transplantation 3(2): 95-104, 1988

The prevention and treatment of cytomegalovirus infection after liver transplantation. Zhonghua Wai Ke Za Zhi 43(9): 584-586, 2005

Diagnosis, prevention and therapy of cytomegalovirus infection in patients treated with bone marrow transplantation. Acta Haematologica Polonica 26(2): 153-162, 1995

Cytomegalovirus infections following transplantation: diagnosis, prevention and treatment. Revue Medicale de la Suisse Romande 108(8): 697-701, 1988

Cytomegalovirus after renal transplantation - diagnosis, prevention and treatment. Deutsche Medizinische Wochenschrift 140(8): 612-615, 2015

Cytomegalovirus infection following marrow transplantation: risk, treatment, and prevention. Birth Defects Original Article Series 20(1): 101-117, 1984

The prevention and treatment of cytomegalovirus infection in haematopoietic stem cell transplantation. Cancer Immunology, ImmunoTherapy 58(9): 1481-1488, 2009

Treatment and prevention of cytomegalovirus infection in heart and lung transplantation: an update. Expert Opinion on PharmacoTherapy 17(12): 1611-1622, 2017

Advances in the diagnosis, treatment, and prevention of cytomegalovirus infections after liver transplantation. Gastroenterology Clinics of North America 22(2): 351-366, 1993

Diagnosis and treatment of cytomegalovirus infection after renal transplantation. Transplantation Proceedings 32(7): 1930-1931, 2000

Human cytomegalovirus infection diagnosis treatment and prevention. M-S (Medecine Sciences) 6(6): 544-551, 1990

Cytomegalovirus infection and disease after bone marrow transplantation: epidemiology, prevention, and treatment. Bone Marrow Transplantation 7 Suppl 3: 52-56, 1991

Prevention and treatment of cytomegalovirus infection and disease after bone marrow transplantation in the 1990s. Bone Marrow Transplantation 8(1): 7-11, 1991

Cytomegalovirus infection after transplantation. Virological diagnosis, antiviral treatment. Pathologie-Biologie 41(8): 724-730, 1993