EurekaMag
+ Translate
+ Most Popular
The pigeon tick (Argas reflexus): its biology, ecology, and epidemiological aspects
Prevalence of hemoglobin abnormalities in Kebili (Tunisian South)
Lipogranuloma: a preventable complication of dacryocystorhinostomy
Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency
Bees from the Belgian Congo. The acraensis group of Anthophora
Placing gingival retraction cord
Total serum IgE, allergy skin testing, and the radioallergosorbent test for the diagnosis of allergy in asthmatic children
Acariens plumicoles Analgesoidea parasites des oiseaux du Maroc
Injuries of terminal phalanges of the fingers in children
Biology of flowering and nectar production in pear (Pyrus communis)
Das Reliktvorkommen der Aspisviper (Vipera aspis L.) im Schwarzwald
Hydrological modelling of drained blanket peatland
Pathologic morphology and clinical significance of the anomalous origin of the left circumflex coronary artery from the right coronary artery. General review and autopsy analysis of 30 cases
Cyto genetic analyses of lymphocyte cultures after exposure to calcium cyclamate
Axelrodia riesei, a new characoid fish from Upper Rio Meta in Colombia With remarks concerning the genus Axelrodia and description of a similar, sympatric, Hyphessobrycon-species
Favorable evolution of a case of tuberculosis of pancreas under antibiotic action
RIFM fragrance ingredient safety assessment, Valencene, CAS Registry Number 4630-07-3
Parenteral microemulsions: an overview
Temperate pasture: management for grazing and conservation
Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation
Thermal expansion and cracking of three confined water-saturated igneous rocks to 800C
Revision of the genera of the tribe Stigmoderini (Coleoptera: Buprestidae) a discussion of phylogenetic relationships
Anal tuberculosis. Report of a case
Gastric tuberculosis in the past and present
Adaptive responses of the cardiovascular system to prolonged spaceflight conditions: assessment with Holter monitoring

Parenteral microemulsions: an overview


Parenteral microemulsions: an overview



International Journal of Pharmaceutics 355(1-2): 19-30



ISSN/ISBN: 0378-5173

PMID: 18295991

DOI: 10.1016/j.ijpharm.2008.01.004

Parenteral delivery of the hydrophobic drugs is a very challenging task. The conventional approaches such as use of co-solvents, oily vehicles and modern approaches such as mixed micelles, liposomes, complexation with cyclodextrins and emulsions have several limitations. Microemulsions have evolved as a novel vehicle for parenteral delivery of the hydrophobic drugs. Their interesting features such as spontaneity of formation, ease of manufacture, high solubilization capacity and self-preserving property make them the vehicle of choice. The review focuses on the excipients available for formulation of the parenteral microemulsions and describes the investigations reported for the various classes of therapeutic agents.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 032718760

Download citation: RISBibTeXText

Related references

Development and evaluation of lorazepam microemulsions for parenteral delivery. Aaps Pharmscitech 9(3): 966-971, 2008

Design and evaluation of microemulsions for improved parenteral delivery of propofol. Aaps Pharmscitech 9(1): 138-145, 2008

Microemulsions: An overview. Journal of Dispersion Science and Technology 18(4): 301-367, 1997

Microemulsions: A Contemporary Overview. Journal of Dispersion Science and Technology 1(4): 423-464, 1980

Lecithin-based oil-in-water microemulsions for parenteral use: pseudoternary phase diagrams, characterization and toxicity studies. Journal of Pharmaceutical Sciences 92(7): 1428-1437, 2003

Surfactant association structures, microemulsions, and emulsions in foods: an overview. ACS Symposium series American Chemical Society: 48) 7-24, 1991

Preparation, characterization, sterility validation, and in vitro cell toxicity studies of microemulsions possessing potential parenteral applications. Drug Development and Industrial Pharmacy 39(2): 240-251, 2013

In situ phase transition of microemulsions for parenteral injection yielding lyotropic liquid crystalline carriers of the antitumor drug bufalin. Colloids and Surfaces. B Biointerfaces 173: 217-225, 2019

Blockcopolymers in microemulsions differential heats of solution and shift of the percolation temperature in W/O microemulsions. Helvetica Chimica Acta 73(1): 213-220, 1990

Determination of drug partition in microemulsions measured by electrokinetic chromatography with non-ionic microemulsions. Pharmaceutical Research (New York) 14(11 Suppl): S48, 1997

Chemical reactions in microemulsions application of microemulsions as solvents for organic synthesis. Journal of Chemical Research (Synopses) (4): 92-93, 1991

Microemulsions vs chitosan derivative-coated microemulsions for dermal delivery of 8-methoxypsoralen. International Journal of Nanomedicine 14: 2327-2340, 2019

Stable microemulsions for the administration of fatty acids to humans or to animals, and use of these microemulsions. Official Gazette of the United States Patent and Trademark Office Patents 1265(5), 2002

Gelation of microemulsions and release behavior of sodium salicylate from gelled microemulsions. European Journal of Pharmaceutics and Biopharmaceutics: Official Journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik E.V 71(2): 297-302, 2009

Ionic liquids in microemulsions-a concept to extend the conventional thermal stability range of microemulsions. Chemistry 16(3): 783-786, 2010