Perinuclear antineutrophil cytoplasmic autoantibodies and anti-Saccharomyces cerevisiae antibodies as serological markers are not specific in the identification of Crohns disease and ulcerative colitis

Anand,V.; Russell,A.S.; Tsuyuki,R.; Fedorak,R.

Canadian Journal Of Gastroenterology: 1, 33-36

2008


Accession: 032759936

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Abstract
OBJECTIVE: To evaluate the diagnostic accuracy of perinuclear antineutrophil cytoplasmic autoantibodies (pANCAs) and anti-Saccharomyces cerevisiae antibodies (ASCAs), as single agents and in combination, for the diagnosis of Crohn's disease (CD) and ulcerative colitis (UC), including in cases of indeterminate colitis (IC). METHODS: The sera from a total of 98 patients were studied: 77 with CD, 16 with UC and five with IC.