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Platelet function and bleeding time in uremia relationship to hemodialysis

Journal of the American Society of Nephrology 3(3): 395

Platelet function and bleeding time in uremia relationship to hemodialysis

Accession: 032846150

Related references

Brophy, D.F.; Martin, E.J.; Carr, S.L.; Kirschbaum, B.; Carr, M.E., 2006: The effect of uremia on platelet contractile force, clot elastic modulus and bleeding time in hemodialysis patients. Introduction: Uremic bleeding frequently occurs in dialysis patients. Although its mechanism is not well characterized, acquired platelet dysfunction has been implicated in its pathogenesis. Skin bleeding time has been used to characterize platel...

Noris, M.; Macconi, D.; Corna, D.; Todeschini, M.; Remuzzi, G., 1999: The effect of guanidinosuccinic acid of inhibiting platelet function and prolonging bleeding time in uremia is mediated by nitric oxide. Journal of the American Society of Nephrology 10(PROGRAM AND ABSTR ISSUE): 297A, Sept

Gerrard, J.M.; Docherty, J.C.; Israels, S.J.; Cheang, M.S.; Bishop, A.J.; Kobrinsky, N.L.; Schroeder, M.L.; Israels, E.D., 1989: A reassessment of the bleeding time: association of age, hematocrit, platelet function, von Willebrand factor, and bleeding time thromboxane B2 with the length of the bleeding time. In order to provide an overview of the relative contribution of platelet, von Willebrand factor, and other abnormalities to patients with clinical bleeding difficulties, we performed a retrospective survey of coagulation studies on 569 individuals...

Fabris F.; Cordiano I.; Randi M.L.; Casonato A.; Montini G.; Zacchello G.; Girolami A., 1991: Effect of human recombinant erythropoietin on bleeding time platelet number and function in children with end stage renal disease maintained by hemodialysis. We studied platelet number and function in nine anaemic children with end-stage renal disease during a clinical trial with recombinant human erythropoietin (rHu-EPO). All the children showed a correction in both haematocrit and haemoglobin levels...

Sarrias X.; Martinez Brotons F.; Gabas J.; Alsina J., 1984: Platelet function in chronic uremia effect of hemodialysis. Kidney International 26(2): 218-219

Jørgensen, K.A.; Ingeberg, S., 1979: Platelets and platelet function in patients with chronic uremia on maintenance hemodialysis. In 20 chronic uremic patients on maintenance hemodialysis, who were not taking any medication known to affect platelet function, the following investigations were carried out: platelet count, fibrin/fibrinogen degradation products, fibrinogen and...

Gaspari, F.; Viganò, G.; Orisio, S.; Bonati, M.; Livio, M.; Remuzzi, G., 1987: Aspirin prolongs bleeding time in uremia by a mechanism distinct from platelet cyclooxygenase inhibition. We reported that aspirin (ASA) abnormally prolongs bleeding time (BT) in uremia. The present study was designed to investigate whether (a) the abnormally prolonged post-ASA BT in uremia is due to different ASA pharmacokinetics and bioavailability...

Krawczyk, W.; Dmoszyńska, A.; Marczewski, K.; Rózyc, P., 1994: Change of platelet function after the beginning of repeated hemodialysis treatment in patients with uremia. The disturbances of platelet function in end-stage renal failure varies in dialysed and non-dialysed patients. We examined some platelet function in 11 uremic patients treated conservatively (TC) and, again in the same patients, 3-month after the...

Remuzzi, G.; Livio, M.; Marchiaro, G.; Mecca, G.; De-Gaetano, G., 1978: Bleeding in renal failure altered platelet function in chronic uremia only partially corrected by hemo dialysis. Bleeding time, blood loss and platelet retention by glass beads, measured by standardized techniques, were significantly altered in 30 non-thrombocytopenic patients with chronic renal failure undergoing maintenance hemodialysis. Bleeding time or b...

Mezzano, D.; Tagle, R.; Panes, O.; Pérez, M.; Downey, P.; Muñoz, B.; Aranda, E.; Barja, P.; Thambo, S.; González, F.; Mezzano, S.; Pereira, J., 1996: Hemostatic disorder of uremia: the platelet defect, main determinant of the prolonged bleeding time, is correlated with indices of activation of coagulation and fibrinolysis. Several parameters of primary hemostasis and markers of activation of coagulation and fibrinolysis were measured in 48 patients with severe (creatinine clearance < 20 ml/min) chronic renal failure (CRF) without dialysis and disease or drugs aff...