Probes for narcotic receptor mediated phenomena 22 1 Synthesis and characterization of optically pure -4- -alpha- -4-propyl-2,5-dimethyl-1-piperazinyl-3-methoxybenzyl-N,N-diethylbenzamide, SNC 121, a novel high affinity and selective ligand for delta opioid receptors
Calderon, S.N.; Bertha, C.M.; Gutkind, J.S.; Xu, H.; Partilla, J.S.; Rothman, R.B.; Rice, K.C.
Journal of Labelled Compounds and Radiopharmaceuticals 38(9): 847-850
1996
ISSN/ISBN: 0362-4803
Accession: 032958102
The synthesis of unlabelled and labelled SNC 121, a selective nonpeptide ligand for the delta opioid receptor is reported. (3H)SNC 121 of specific activity of 26.8 Ci/mmol, was synthesized by catalytic tritiation of the optically pure precursor SNC 80.
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