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Protective immunity induced by the ferritin DNA vaccine of Schistosoma japonicum in mice


Protective immunity induced by the ferritin DNA vaccine of Schistosoma japonicum in mice



Zhongguo Bingyuan Shengwuxue Zazhi: 8, 601-604



A study was conducted to evaluate the protective immunity induced by a DNA vaccine co-expressing granulocyte macrophage colony stimulating factor (GMCSF) and Schistosoma japonicum ferritin (SjFer) in mice. The DNA of pGMC/SjFer was prepared. The gene of GMCSF-SjFer was amplified using polymerase chain reaction (PCR), digested using restriction endonuclease, and cloned into the eukaryotic expression vector proVAX to construct the recombinant plasmid proVAX/GMCSF-SjFer.

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