EurekaMag.com logo
+ Site Statistics
References:
54,215,046
Abstracts:
30,230,908
PMIDs:
28,215,208
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Pseudodementia: a slow death



Pseudodementia: a slow death



Neuropsychology Review 4(2): 71-90



The clinical term "pseudodementia" has remained a permanent nosological entity in the literature for over 100 years. Indeed, recognition of the fact that clinical symptoms associated with reversible neuropsychiatric conditions can mimic irreversible disorders was known as early as the middle of the 19th century. The importance of the term lies in the inherent assumption that the presenting dementia is not real, or is at least reversible, and therefore treatable. Nonetheless, there continues to be controversy regarding the validity and appropriate clinical use of the term. This article reviews the evolution and clinical utility of the term pseudodementia and attempts to redirect investigative efforts toward an understanding of the neuroanatomical substrates that underlie depression and cognitive impairment in the elderly. Based on a critical analysis of the relevant literatures, a subcortical-frontal neuroanatomical substrate of late-life depression is supported. Further, the presence of leukoaraiosis, as measured by magnetic resonance imaging, is proposed as a potential neurobiological marker that contributes to the depressed mood, cognitive impairment, and later cognitive deterioration of some elderly depressed.

(PDF emailed within 0-6 h: $19.90)

Accession: 033019812

Download citation: RISBibTeXText

PMID: 8061683

DOI: 10.1007/bf01874829



Related references

Pseudodementia, what are we talking about? Part I: In search of Wernicke's pseudodementia. L'encephale 41(2): 130-136, 2016

On the concepts of pseudodementia and pseudo-pseudodementia. Rivista Sperimentale di Freniatria E Medicina Legale Delle Alienazioni Mentali 86: 693-731, 1962

Pseudodementia and depressive pseudodementia. Kariya, T, Nakagawara, M Affective disorders: Perspectives on basic research and clinical practice: 61-72, 1993

Slow virus infections of the central nervous system: a concept of a slow cell death. Immunitat und Infektion 3(5): 211-218, 1975

The slow, slow death of clinical engineering. Biomedical Instrumentation & Technology 35(5): 289-289, 2002

Quick death, slow death. I've learned from both. Geriatrics 64(8): 6-7, 14, 2010

Slow/slow and fast/slow atrioventricular nodal reentrant tachycardia use anatomically separate retrograde slow pathways. Circulation 100(18 SUPPL ): I 65, Nov 2, 1999

Electrogram patterns in slow-fast, slow-slow and fast-slow AVNRT suggesting a very proximal location of the lower common pathway of the reentrant circuit. European Heart Journal 17(ABSTR SUPPL ): 402, 1996

Slow death for ddt. American Forests 75(11): 16-20, 1969

Slow death. Tennessee Medicine 90(4): 125-126, 1997

Electrophysiological and anatomical differences of the slow pathway between the fast-slow form and slow-slow form of atrioventricular nodal reentrant tachycardia. Europace 16(4): 551-557, 2014

Slow death of the autopsy. Human Pathology 15(2): 198-199, 1984

A slow death of the mind. Newsweek 104(24): 56-62, 1984

1:3. The slow death of a village. A Common Place: 8-10, 2002

Slow death by red tape. New harbinger 6(5): 19, 1979