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Slice-selective images of free radicals in mice with modulated field gradient electron paramagnetic resonance (EPR) imaging

Slice-selective images of free radicals in mice with modulated field gradient electron paramagnetic resonance (EPR) imaging

Magnetic Resonance in Medicine 59(4): 885-890

Continuous wave (CW) electron paramagnetic resonance (EPR) imaging can be used to obtain slice-selective images of free radicals without measuring three-dimensional (3D) projection data. A method that incorporated a modulated magnetic field gradient (MFG) was combined with polar field gradients to select a slice in the subject noninvasively. The slice-selective in vivo EPR imaging of triarylmethyl radicals in the heads of live mice is reported. 3D surface-rendered images were successfully obtained from slice-selective images. In the experiment in mice, a slice thickness of 1.8 mm was achieved.

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Accession: 033411587

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PMID: 18383284

DOI: 10.1002/mrm.21547

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