+ Translate
+ Most Popular
Gaucher's disease;thirty-two years experience at Siriraj Hospital
A study of Macrobathra Meyrick from China (Lepidoptera, Cosmopterigidae)
First occurrence in ores of tetragonal chalcocite
Effects of trace element nutrition on sleep patterns in adult women
N.Z. range management guidelines. 2. Design of grazing management systems for tussock country
A case of lipoma of the esophagus
A revision of world Acanthosomatidae (Heteroptera: Pentatomidae): keys to and descriptions of subfamilies, tribes and genera, with designation of types
Life history of the coronate scyphozoan Linuche unguiculata (Swartz, 1788)
Perceptual restoration of obliterated sounds
Mutagenicity studies on two chromium(III) coordination compounds
The formation of the skeleton. I. Growth of a long bone. 1st appearance of a center of calcification
Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis
The joint commission: four key root causes loom large in sentinel event data
Treatment of vitiligo with topical 15% lactic acid solution in combination with ultra violet-A
Behaviour of dairy cows within three hours after feed supply: I. Influence of housing type and time elapsing after feed supply
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Management and control of patients with type 2 diabetes mellitus in Lebanon: results from the International Diabetes Management Practices Study (IDMPS)
The diet composition and nutritional knowledge of patients with anorexia nervosa
Physoporella croatica Herak, 1958 of the Slovak karst Anisian (Slovakia, the West Carpathians Mts.)
Bright lights, big noise. How effective are vehicle warning systems?
Ein Plesiosaurier-Rest mit Magensteinen aus mittlerem Lias von Quedlinburg
Incidence of Chlamydia trachomatis in patients with sterility
Monster soup: the microscope and Victorian fantasy
Preliminary tests with residual sprays against poultry lice
Duration of the life of plants in phylogeny

Surface change of the mammalian lens during accommodation

Surface change of the mammalian lens during accommodation

American Journal of Physiology. Cell Physiology 294(6): C1430-C1435

ISSN/ISBN: 0363-6143

PMID: 18385280

DOI: 10.1152/ajpcell.90623.2007

Classical theories suggest that the surface area of the crystalline lens changes during accommodation while the lens volume remains constant. Our recent work challenged this view by showing that the lens volume decreases as the lens flattens during unaccommodation. In this paper we investigate 1) the magnitude of changes in the surface of the in vitro isolated cow lens during simulated accommodation, as well as that of human lens models, determined from lateral photographs and the application of the first theorem of Pappus; and 2) the velocity of the equatorial diameter recovery of prestretched cow and rabbit lenses by using a custom-built software-controlled stretching apparatus synchronized to a digital camera. Our results showed that the in vitro cow lens surface changed in an unexpected manner during accommodation depending on how much tension was applied to flatten the lens. In this case, the anterior surface initially collapsed with a reduction in surface followed by an increase in surface, when the stretching was applied. In the human lens model, the surface increased when the lens unaccommodated. The lens volume always decreases as the lens flattens. An explanation for the unexpected surface change is presented and discussed. Furthermore, we determined that the changes in lens volume, as reflected by the speed of the equatorial diameter recovery in in vitro cow and rabbit lenses during simulated accommodation, occurred within a physiologically relevant time frame (200 ms), implying a rapid movement of fluid to and from the lens during accommodation.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 033591296

Download citation: RISBibTeXText

Related references

Studies on dynamic changes of crystalline lens due to accommodation. Report II. A study on changes of anterior surface of lens during accommodation. Nippon Ganka Gakkai Zasshi 80(9): 979-983, 1976

Effect of change in central lens thickness and lens shape on age-related decline in accommodation. Journal of cataract and refractive surgery 32(11): 1897-8; author reply 1898, 2006

Change in human lens dimensions, lens refractive index distribution and ciliary body ring diameter with accommodation. Biomedical Optics Express 9(3): 1272-1282, 2018

Thickness of the human lens capsule Correlation with lens shape during accommodation and practical consequence for cataract surgery designed to restore accommodation. IOVS 40(4): S887, 1999

Volume change of the ocular lens during accommodation. American Journal of Physiology. Cell Physiology 293(2): C797-C804, 2007

Ocular lens does not change volume during accommodation. American Journal of Physiology. Cell Physiology 293(5): C1727, 2007

Surface and volume changes in the lens during accommodation. Investigative Ophthalmology and Visual Science 52(6): 3698, 2011

The change in shape and internal form of the lens of the eye on accommodation. Experimental Eye Research 15(4): 441-459, 1973

Change in shape of the aging human crystalline lens with accommodation. Vision Research 45(1): 117-132, 2005

Change of Tension on the Lens Capsules during Accommodation and under the Influence of Various Drugs. British Medical Journal 1(3393): 46-50, 1926

The change of the equivalent refractive index of the crystalline lens during accommodation. IOVS 42(4): S9, 2001

OCT-based full crystalline lens shape change during accommodation in vivo. Biomedical Optics Express 8(2): 918-933, 2017

The stress on the anterior lens surface during human in vivo accommodation. British Journal of Ophthalmology 92(3): 348-350, 2008

Effect of anterior zonule transection on the change in lens diameter and power in cynomolgus monkeys during simulated accommodation. Investigative Ophthalmology and Visual Science 50(8): 4017-4021, 2009

Constant volume of the human lens and decrease in surface area of the capsular bag during accommodation: an MRI and Scheimpflug study. Investigative Ophthalmology and Visual Science 50(1): 281-289, 2009