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The bile acid repression of cholesterol 7-alpha-hydroxylase gene transcription may be mediated through multiple elements in the promoter


The bile acid repression of cholesterol 7-alpha-hydroxylase gene transcription may be mediated through multiple elements in the promoter



Protein Engineering 8(Suppl ): 76



ISSN/ISBN: 0269-2139


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(PDF emailed within 1 workday: $29.90)

Accession: 033726444

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Related references

Repression of cholesterol 7 alpha-hydroxylase transcription by bile acids is mediated through protein kinase C in primary cultures of rat hepatocytes. Journal of Lipid Research 36(6): 1359-1369, 1995

Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids. Journal of Lipid Research 42(9): 1402-1412, 2001

Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase gene transcription. Hepatology 21(2): 501-510, 1995

The bile acid responsive element is located in the proximal promoter of the cholesterol 7-alpha-hydroxylase gene. FASEB Journal 8(7): A1250, 1994

The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors. Journal of Biological Chemistry 276(33): 30708-30716, 2001

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The negative effects of bile acids and tumor necrosis factor-a on the transcription of cholesterol 7a-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4. A novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors. The Journal of Biological Chemistry 276(33): 708-16, 2001

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