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The effect of taurine supplementation on the ototoxicity of neomycin in guinea pigs

The effect of taurine supplementation on the ototoxicity of neomycin in guinea pigs

European Archives of Oto-Rhino-Laryngology 247(1): 37-39

Experiments have been performed to examine the effects of taurine supplementation on the ototoxicity of neomycin. It was found that concurrent administration of taurine and neomycin produced a greater degree of ototoxicity, as evidenced by increases in hearing thresholds, than with neomycin alone. The results are discussed in light of a recently proposed mechanism of aminoglycoside ototoxicity.

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Accession: 033784855

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PMID: 2310548

DOI: 10.1007/bf00240947

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