+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The low-virulent African swine fever virus induces enhanced expression and production of relevant regulatory cytokines on porcine macrophages in comparison to the highly virulent ASFV/L60



The low-virulent African swine fever virus induces enhanced expression and production of relevant regulatory cytokines on porcine macrophages in comparison to the highly virulent ASFV/L60



Archives Of Virology3: 10, 1845-1854



The impact of infection by the low-virulent ASFV/NH/P68 (NHV) and the highly virulent ASFV/L60 (L60) isolates on porcine macrophages was assessed through the quantification of IFN alpha , TNF alpha , IL12p40, TGF beta and ASFV genes by real-time PCR at 2, 4 and 6 h post-infection. Increased IFN alpha , TNF alpha and IL12p40 expression was found in infection with NHV, in which expression of TGF beta was lower than in infection with L60.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 033861491

Download citation: RISBibTeXText

DOI: 10.1007/s00705-008-0196-5


Related references

The low-virulent African swine fever virus (ASFV/NH/P68) induces enhanced expression and production of relevant regulatory cytokines (IFNalpha, TNFalpha and IL12p40) on porcine macrophages in comparison to the highly virulent ASFV/L60. Archives of Virology 153(10): 1845-1854, 2008

Expression at mRNA level of cytokines and A238L gene in porcine blood-derived macrophages infected in vitro with African swine fever virus (ASFV) isolates of different virulence. Archives of Virology 148(11): 2077-2097, 2003

The replication of virulent and attenuated strains of African swine fever virus in porcine macrophages. Archives of Virology 61(3): 217-225, 1979

Patterns of cellular gene expression in swine macrophages infected with highly virulent classical swine fever virus strain Brescia. Virus Research 138(1-2): 89-96, 2008

Apoptosis in porcine macrophages infected in vitro with African swine fever virus (ASFV) strains with different virulence. Archives of Virology 154(9): 1441-1450, 2009

Granulocyte-macrophage colony stimulating factor promotes prolonged survival and the support of virulent infection by African swine fever virus of macrophages generated from porcine bone marrow and blood. Journal of General Virology 77: 2625-2630, 1996

The growth of virulent African swine fever virus in pig monocytes and macrophages. Journal of General Virology 38(1): 183-186, 1978

Comparative precipitation studies between the highly-virulent virus of European swine fever, swine-fever-virus split products and precipitating swine-fever antigens from the organs of swine-fever infected pigs. Zentralblatt für Veterinarmedizin. Reihe B. Journal of Veterinary Medicine. Series B 24(10): 830-834, 1977

Comparative precipitation studies of highly virulent virus of European swine fever, swine fever virus cleavage products and precipitating swine fever antigens from the organs of swine fever-infected pigs. Zentralblatt fur Veterinarmedizin 24B(10): 830-834, 1977

Comparative precipitation studies between highly virulent virus of European swine fever, swine fever virus split products and precipitating swine fever antigens from the organs of swine fever infected pigs. Zentralblatt fur Veterinarmedizin: Reihe B: 24 (10) 830-834, 1977

Evidence of hemolysis in pigs infected with highly virulent African swine fever virus. Veterinary World 9(12): 1413-1419, 2016

Genomic analysis of highly virulent Georgia 2007/1 isolate of African swine fever virus. Emerging Infectious Diseases 17(4): 599-605, 2011

Comparative precipitation studies between highly virulent virus of European swine fever, swine fever virus split products and precipitating swine fever antigens from the organs. Zentralblatt fur Veterinarmedizin: Reihe B: 24 (10) 830-834, 1977

Comparative precipitation studies between highly virulent virus of European swune fever, swine fever split products and precipitating swine fever antigens from the organs of swine fever infected pigs. 1980

Macrophage transcriptional responses following in vitro infection with a highly virulent African swine fever virus isolate. Journal of Virology 80(21): 10514-10521, 2006