+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The organophosphate paraoxon has no demonstrable effect on the murine immune system following subchronic low dose exposure



The organophosphate paraoxon has no demonstrable effect on the murine immune system following subchronic low dose exposure



International Journal Of Immunopathology And Pharmacology: 4, 891-901



Paraoxon is the bioactive metabolite of the organophosphate pesticide parathion. Desulphuration of parathion by liver enzymes or sunlight results in the formation of paraoxon which inhibits acetylcholine esterase (AChE) activity. In the present study, we analyzed the effect of a 6-week, subchronic treatment with two different daily intraperitoneal doses (30 or 40 nmol) of paraoxon on the immune system of BALB/c mice.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 033884337

Download citation: RISBibTeXText


Related references

The organophosphate paraoxon has no demonstrable effect on the murine immune system following subchronic low dose exposure. International Journal of Immunopathology and Pharmacology 21(4): 891-901, 2009

Effects of some organophosphate pesticides on the murine immune system following subchronic exposure ii. Archives of Pharmacal Research 9(3): 183-188, 1986

Effects of some organophosphate pesticides on the murine immune system following subchronic exposure i. Archives of Pharmacal Research 9(3): 175-182, 1986

In vivo metoclopramide protection of cholinesterase from paraoxon inhibition: direct comparison with pralidoxime in subchronic low-dose exposure. Journal of Applied Toxicology 24(4): 257-260, 2004

High-dose intravenous paraoxon exposure does not cause organophosphate-induced delayed neuropathy (OPIDN) in mini pigs. Journal of Applied Toxicology 21(4): 263-268, 2001

Oxidative stress resulting from exposure of a human salivary gland cells to paraoxon: an in vitro model for organophosphate oral exposure. Toxicology in Vitro 28(5): 715-721, 2014

Some immune reactions of murine-leukemia viruses demonstrable within a completely isologous system. Virus inducing cancer: Implications for therapy, 25-50, 1966

Effect of subchronic 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on immune system and target gene responses in mice: Calculation of benchmark doses for CYP1A1 and CYP1A2 related enzyme activities. Archives of Toxicology 71(6): 372-382, 1997

Effects of ochratoxin A on the mouse immune system after subchronic exposure. Food and Chemical Toxicology 33(12): 1005-1011, 1995

Usefulness of administration of non-organophosphate cholinesterase inhibitors before acute exposure to organophosphates: assessment using paraoxon. Journal of Applied Toxicology 33(9): 894-900, 2013

Effects of subchronic exposure to Caramel Colour III on the immune system in mice. Food & Chemical Toxicology. 32(1): 7-13, 1994

Comparison of two pre-exposure treatment regimens in acute organophosphate (paraoxon) poisoning in rats: tiapride vs. pyridostigmine. Toxicology and Applied Pharmacology 219(2-3): 235-240, 2007