+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Aerosol inhalation device providing improved aerosol delivery



Aerosol inhalation device providing improved aerosol delivery



Official Gazette of the United States Patent and Trademark Office Patents 1246(3)



Improved aerosol inhalation devices are provided. The devices include an aerosol source for generating an aerosol; a first conduit, having a proximal end, the first conduit providing passage of the aerosol to the patient; a first chamber at the proximal end of the first conduit, adjacent to the aerosol source; a second conduit providing passage of gaseous medium from the patient; a second chamber; and a first valve disposed between the first chamber and the second chamber. The first valve remains closed during exhalation by the patient and opens at least partially during inhalation. The device also includes a second valve disposed between the second conduit and the second chamber, which remains closed during inhalation by the patient and opens at least partially during exhalation by said patient. The gaseous medium exhaled by the patient can optionally contain material of which the aerosol is formed, such as liquid droplets. The invention also provides methods for making the devices, and for using the devices to deliver therapeutic and diagnostic material in aerosol form to a patient.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 034365096

Download citation: RISBibTeXText


Related references

Clinical evaluation of a serum immunosuppressive (IS) substance in various diseases. Gan to Kagaku Ryoho. Cancer and ChemoTherapy 9(12): 2104-2112, 1982

Physicochemical characterization and adsorption behavior of Ca/Al chloride hydrotalcite-like compound towards removal of nitrate. Journal of Hazardous Materials 190(1-3): 659-668, 2011

Physicochemical characterization and aerosol dispersion performance of organic solution advanced spray-dried cyclosporine A multifunctional particles for dry powder inhalation aerosol delivery. International Journal of Nanomedicine 8: 1269-1283, 2013

The development of a nonintrusive home-based physiologic signal measurement system. Telemedicine Journal and E-Health 11(4): 487-495, 2005

Results of the treatment of patients with tuberculosis of the skin. Vestnik Dermatologii i Venerologii 41(3): 59-62, 1967

A novel acoustic sensing system for on-line hydrogen measurements. Sensors and Actuators B: Chemical 32(3): 233-237, 1996

Tuning acoustic and mechanical properties of materials for ultrasound phantoms and smart substrates for cell cultures. Acta Biomaterialia 49: 368-378, 2017

A novel aerobic respiratory chain-linked NADH oxidase system in Zymomonas mobilis. Journal of Bacteriology 177(17): 5176-5178, 1995

Particle Size of Inhalation Aerosol Systems I: Production of Homogenous Dispersions. Drug Development and Industrial Pharmacy 6(6): 645-651, 1980

Aerosol deposition measurements detect papain induced emphysema in isolated lungs. American Review of Respiratory Disease 141(4 Part 2): A522, 1990

Aerosol inhalation apparatus us patent 4823784 april 25 1989. Official Gazette of the United States Patent and Trademark Office Patents 1101(4): 2306, 1989

Determining the degree of gelatinization in parboiled rice: Comparison of a subjective and an objective method. Cereal Chemistry 70(2): 226-230, 1993

Inhalation sensitization to trypsin. Journal of Allergy 39(1): 11-16, 1967

Aerosol inhalation and depth of deposition in the human lung. The effect of airway obstruction and tidal volume inhaled. Archives of Environmental Health 32(3): 131-137, 1977

A new ingestion method for long-term morphine intoxication in rat. Pharmacology Biochemistry and Behavior 17(3): 495-501, 1982