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Age-related macular degeneration and antioxidant vitamins: recent findings

Age-related macular degeneration and antioxidant vitamins: recent findings

Current Opinion in Clinical Nutrition and Metabolic Care 13(1): 28-33

ISSN/ISBN: 1363-1950

PMID: 19841580

DOI: 10.1097/mco.0b013e32833308ff

The purpose of the present review is to evaluate the most recent evidence for a role of antioxidant nutrients in the prevention or delay in progression of age-related macular degeneration (AMD), a major cause of visual impairment and blindness in the aging population. Recent human studies (>2008) report a decreased AMD risk with increased intakes of lutein/zeaxanthin, B vitamins, zinc and docosahexaenoic acid but an increased risk with increased intakes of beta-carotene and vitamin E. These latter findings are inconsistent with previous reports (<2008). Findings on the association of certain antioxidants and docosahexaenoic acid support a role for nutrition in a decreased risk of AMD. The inconsistent findings of an increased risk with increased intake of beta-carotene and vitamin E warrants continued investigation into these relationships.

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Accession: 034367971

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