Bovine herpesvirus type 1 deletion mutants, vaccines based thereon, diagnostic kits for detection of bovine herpesvirus type 1

Rijsewijk, F.A.tonius Maria; Van Oirschot, J.T.eodorus

Official Gazette of the United States Patent and Trademark Office Patents 1259(2)


ISSN/ISBN: 0098-1133
Accession: 034502996

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A deletion mutant of bovine herpesvirus type 1 which has a deletion in the glycoprotein gE-gene and which may further have a deletion in the thymidine kinase gene and/or the glycoprotein gI-gene, or have an insertion of a heterologous gene is disclosed. Recombinant nucleic acids which encode the gE-gene or a part thereof are also disclosed, in addition to vaccines and a method of treatment.