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Method of screening substances with a glycidyl methacrylate covered styrene-glycidyl methacrylate polymer



Method of screening substances with a glycidyl methacrylate covered styrene-glycidyl methacrylate polymer



Official Gazette of the United States Patent and Trademark Office Patents 1280(2)



A compound possessing physiological activity is coupled to a styrene-glycidyl methacrylate polymer through a spacer. Compounds that may be used include receptors such as proteins, and 3-[(5-(2,3-dimethoxy-6-methyl-benzoquinonyl)]-2-nonyl-2-propionic a preferred spacer is an ethylene glycol diglycidyl ether derivative. Preferably, the whole surface of the styrene-glycidyl methacrylate polymer in microsphere form is covered with glycidyl methacrylate. The microsphere may be used for isolating and detecting substances such as proteins that bind to the coupled compound.

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Accession: 035298459

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