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Multi-component methodologies in solid-phase organic synthesis

Multi-component methodologies in solid-phase organic synthesis

Current Medicinal Chemistry 6(3): 255-270

Solid-phase organic synthesis, particularly when used in conjunction with combinatorial techniques, is emerging as a revolutionary technology in chemistry. Multi-component reaction systems are particularly valued because several elements of diversity can be introduced in a single transformation thereby expanding the diversity of compound libraries. A variety of multi-component reactions have been successfully adapted for solid-phase technology as described in this review.

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Accession: 035349070

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PMID: 10219102

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