+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Multi-imaging modality tissue mimicking materials for imaging phantoms

Multi-imaging modality tissue mimicking materials for imaging phantoms

Official Gazette of the United States Patent & Trademark Office Patents 1252(3), Nov 20

Tissue-mimicking material suitable for phantoms for use with at least ultrasound and MRI have sections of material in contact with each other which mimic ultrasound and magnetic resonance imaging properties of human tissues, and preferably also computed tomography properties, so that the phantom can be used for the testing of imaging by various types of medical imagers. A suitable tissue-mimicking material for use in phantoms of this type includes an aqueous mixture of large organic water soluble molecules, a copper salt, a chelating agent for binding the copper ions in the salt, and a gel-forming material. Small glass beads may be intermixed therewith to provide a selected ultrasound attenuation coefficient without substantially affecting the MRI properties of the material. Larger glass beads may be used in a section to control primarily the ultrasound backscatter coefficient without significant effect on the ultrasound attenuation coefficient. Tissue-mimicking material that simulates muscle may have smaller glass beads and a higher concentration of gel-forming material than an adjacent section. Such similar materials in contact with one another show relative stability over extended periods of time.

(PDF emailed within 1 workday: $29.90)

Accession: 035349242

Download citation: RISBibTeXText

Related references

Tissue mimicking materials for a multi-imaging modality prostate phantom. Medical Physics 28(4): 688-700, 2001

Prospective tissue-mimicking materials for use in NMR imaging phantoms. Magnetic Resonance Imaging 1(3): 135-141, 1982

Tissue-mimicking phantoms for photoacoustic and ultrasonic imaging. Biomedical Optics Express 2(11): 3193-3206, 2011

Gel wax-based tissue-mimicking phantoms for multispectral photoacoustic imaging. Biomedical Optics Express 9(3): 1151-1163, 2018

Improving the homogeneity of tissue-mimicking cryogel phantoms for medical imaging. Medical Physics 39(11): 6796-6807, 2013

Study of ultrasound stiffness imaging methods using tissue mimicking phantoms. Ultrasonics 54(2): 621-631, 2014

Design and Characterization of Tissue-Mimicking Gel Phantoms for Diffusion Kurtosis Imaging. Medical Physics: -, 2018

Tissue-mimicking gelatin-agar gels for use in magnetic resonance imaging phantoms. Medical Physics 15(4): 629-636, 1988

3D-Printed Tissue-Mimicking Phantoms for Medical Imaging and Computational Validation Applications. 3d Printing and Additive Manufacturing 1(1): 14-23, 2014

Selective sensitivity of Mueller imaging for tissue scattering over absorption changes in cancer mimicking phantoms. Optics and Lasers in Engineering 102: 112-118, 2018

Intraoperative imaging-guided cancer surgery: from current fluorescence molecular imaging methods to future multi-modality imaging technology. Theranostics 4(11): 1072-1084, 2015

Characterization of biomechanical properties of agar based tissue mimicking phantoms for ultrasound stiffness imaging techniques. Journal of the Mechanical Behavior of Biomedical Materials 35: 132-143, 2015

Combined PET/MRI: Multi-modality Multi-parametric Imaging Is Here: Summary Report of the 4th International Workshop on PET/MR Imaging; February 23-27, 2015, Tübingen, Germany. Molecular Imaging and Biology 17(5): 595-608, 2016

Improved continuous light diffusion imaging in single- and multi-target tissue-like phantoms. Physics in Medicine and Biology 43(3): 675-693, 1998

A simple method for determining the coagulation threshold temperature of transparent tissue-mimicking thermal therapy gel phantoms: Validated by magnetic resonance imaging thermometry. Medical Physics 43(3): 1167-1174, 2016