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Multi-label complex for enhanced sensitivity in electrochemiluminescence assay



Multi-label complex for enhanced sensitivity in electrochemiluminescence assay



Official Gazette of the United States Patent & Trademark Office Patents 1237(1), Aug 1



A nucleotide probe complex which enhances the ability to discriminate low level samples in electrochemiluminescent assays. The complex is composed of a platform molecule to which multiple copies of an organometallic electrochemiluminescent label and an oligonucleotide probe are separately attached. Preferably the complex is capped with streptavidin. Use of the complex permits detection of 1000 copies of analyte per sample in less than one hour.

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Accession: 035349269

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