+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Multi-state genetic oscillator

Multi-state genetic oscillator

Official Gazette of the United States Patent & Trademark Office Patents 1282(3), May 18

Provided are methods and compositions for regulating gene expression in a cell. The invention provides recombinant multi-state genetic oscillators containing an adjustable-threshold genetic switch that is periodically activated by an oscillating amount of an activator agent. The activating agent is a gene product expressed from a promoter regulated by the adjustable-threshold switch and thus forms a feedback loop that causes periodic switching of the adjustable-threshold switch between an "on" state and an "off" state. Multi-state genetic oscillators are useful to express one or more genes of interest in a periodic manner without requiring a periodic application of an external activating agent.

(PDF emailed within 1 workday: $29.90)

Accession: 035349585

Download citation: RISBibTeXText

Related references

Mathematical models of circadian one oscillator and multi oscillator system. Carpenter, G A Lectures on Mathematics in The Life Sciences, Vol 19 Some Mathematical Questions in Biology Circadian Rhythms; Symposium, Philadelphia, Pennsylvania, Usa, May 28, 1986 Xii+265p The American Mathematical Society: Providence, Rhode Island, Usa Illus Paper 205-265, 1987

Compact, passively Q-switched, all-solid-state master oscillator-power amplifier-optical parametric oscillator (MOPA-OPO) system pumped by a fiber-coupled diode laser generating high-brightness, tunable, ultraviolet radiation. Applied Optics 48(19): 3839-3845, 2009

Approximate Relativistic Bound State Solutions of the Tietz–Hua Rotating Oscillator for Any ?-State. Few-Body Systems 53(3-4): 473-486, 2012

visPIG--a web tool for producing multi-region, multi-track, multi-scale plots of genetic data. Plos One 9(9): E107497-E107497, 2016

Mathematical models of circadian one- and multi-oscillator systems. Lectures on Mathematics in the Life Sciences 205-265, 1986

Bayesian analysis of multi-state data with individual covariates for estimating genetic effects on demography. Journal of Ornithology 152(2 Supplement): 561-572, 2012

Prostate cancer screening using risk stratification based on a multi-state model of genetic variants. Prostate 75(8): 825-835, 2015

Circadian biology: environmental regulation of a multi-oscillator network. Current Biology 20(7): R322-R324, 2010

The living cell: a complex autodynamic multi-oscillator system?. Cell Biology International 24(8): 569-580, 2000

The multi-oscillator system of circadian rhythms in the Japanese quail. Zoological Science (Tokyo) 17(Supplement): 91, December, 2000

Hierarchical multi-oscillator systems in mammalian circadian clock. Chronobiology International 18(6): 1128-1129, November, 2001

Transition state theory thermal rate constants and RRKM-based branching ratios for the N((2)D) + CH(4) reaction based on multi-state and multi-reference ab initio calculations of interest for the Titan's chemistry. Journal of Computational Chemistry 33(28): 2211-2224, 2012

A hierarchical multi-oscillator network orchestrates the Arabidopsis circadian system. Cell 163(1): 148-159, 2015

The fiddler crab uca spp a model for human multi oscillator circadian organization. International Journal of Chronobiology 7(4): 11, 1981