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Multiblock biodegradable hydrogels for drug delivery and tissue treatment



Multiblock biodegradable hydrogels for drug delivery and tissue treatment



Official Gazette of the United States Patent & Trademark Office Patents 1244(2), Mar 13



Gel-forming macromers including at least four polymeric blocks, at least two of which are hydrophobic and at least one of which is hydrophilic, and including a crosslinkable group are provided. The macromers can be covalently crosslinked to form a gel on a tissue surface in vivo. The gels formed from the macromers have a combination of properties including thermosensitivity and lipophilicity, and are useful in a variety of medical applications including drug delivery and tissue coating.

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Accession: 035349699

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