+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Multicenter prospective validation of a simple endoscopic score for crohns disease



Multicenter prospective validation of a simple endoscopic score for crohns disease



Digestive Disease Week Abstracts & Itinerary Planner : Abstract No S1343



Background: Endoscopic healing has become one of the major goals of Crohn s disease (CD) therapy. The gold standard for CD endoscopic evaluation is the Crohn s disease endoscopic index of severity (CDEIS), which is time consuming and difficult to use. SES-CD has been proposed as a simpler alternative (1). Aims: To evaluate SES-CD reproducibility and clinical correlations. Methods: Clinical history, CDAI and IBDQ were recorded. Blood was drawn for CRP and blood count. CDEIS and SES-CD were independently scored by a pair of experienced endoscopists. The following lesions were assessed in the 5 classic ileocolonic segments: Results: Sixty-two patients were studied. The mean number of ileocolonic segments explored per procedure was 4.6 (range 3-5). Interobserver agreement for SES-CD variables was good to excellent for all segments, with kappa values ranging between 0.76 and 1.00. The interobserver correlation for SES-CD was significantly closer than for the CDEIS (r=0.97 vs 0.87, p<0.0001). Correlations of SES-CD to CRP and CDAI were significant (p<0.002), but not very close (r=0.39 and 0.41), and not significantly better than CDEIS correlations (0.26 and 0.36). Conclusions: This prospective validation study confirmed the reproducibility of the SES-CD. SES-CD is at least as reliable as CDEIS, but is simpler to be scored. Further validation is ongoing.

(PDF emailed within 1 workday: $29.90)

Accession: 035349890

Download citation: RISBibTeXText


Related references

The Crohns disease endoscopic score is a simple index to assess endoscopic severity of Crohns disease. Gastroenterology 122(4 Suppl 1): A-216, 2002

Reproducibility of endoscopic findings in colonic crohn's disease a prospective multicenter interobserver variation study. Gastroenterology 90(5 PART 2): 1555, 1986

Correlations between clinical activity endoscopic severity and biological parameters in colonic or ileocolonic crohns disease cicd a multicenter prospective study of 121 cases. Gastroenterology 100(5 PART 2): A202, 1991

Development and validation of a crohn's disease endoscopic index reflecting lesion severity cdeis a prospective multicentric study on 188 patients. Gastroenterology 94(5 PART 2): A286, 1988

Validation of the Capsule Endoscopy Crohn's Disease Activity Index (CECDAI or Niv score): a multicenter prospective study. Endoscopy 44(1): 21-26, 2012

Prospective, multicenter validation of a clinical risk score for left atrial arrhythmogenic substrate based on voltage analysis: DR-FLASH score. Heart Rhythm 12(11): 2207-2212, 2016

Validation du score AFC pour prdire la mortalit opratoire aprs chirurgie pour cancer colorectal ou diverticulite: A. Alves, Y. Panis, G. Mantion, K. Slim, F. Kwiatkowski, E. Vicaut The AFC score: validation of a 4-item predicting score of postoperative mortality after colorectal resection for cancer or diverticulitis: results of a prospective multicenter study in 1,049 patients. Ann Surg 2007;246:91-96. Journal de Chirurgie 144(6): 553-0, 2007

The AFC score: validation of a 4-item predicting score of postoperative mortality after colorectal resection for cancer or diverticulitis: results of a prospective multicenter study in 1049 patients. Annals of Surgery 246(1): 91-96, 2007

Validation of a genetic risk score for atrial fibrillation: A prospective multicenter cohort study. Plos Medicine 15(3): E1002525, 2018

Operative radicality and prophylaxis with azulfidine in crohns disease a prospective multicenter trial. Langenbecks Archiv fuer Chirurgie 364: 427-430, 1984

Presentation of a prospective regional multicenter study in ulcerative colitis and crohns disease. Scandinavian Journal of Gastroenterology Supplement 18(86): 39, 1983

Ultrasonographic-surgical correlation in patients with Crohns disease A prospective multicenter study. Gastroenterology 104(4 SUPPL ): A713, 1993

Prospective Validation of Objective Prognostic Score for Advanced Cancer Inpatients in South Korea: A Multicenter Study. Journal of Palliative Medicine 20(1): 65-68, 2016

Validation of a simple proctology examination for evaluation of anoperineal Crohns disease. Gastroenterology 118(4 Suppl 2 Part 2): AGA A1370, 2000

Psychosocial intervention in Crohns disease Results of a prospective randomized multicenter treatment study. Gastroenterology 108(4 SUPPL ): A948, 1995