+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Prophylactic and therapeutic treatment of the ductal epithelium for a mammary gland for cancer



Prophylactic and therapeutic treatment of the ductal epithelium for a mammary gland for cancer



Official Gazette of the United States Patent and Trademark Office Patents 1253(2)



The present invention provides prophylactic and therapeutic methods of treating the ductal epithelium of an exocrine gland, in particular a mammary gland, for disease, in particular cancer. The methods comprise contacting the ductal epithelium of the exocrine gland with an epithelium-destroying agent, preferably by ductal cannulation, so as to realize a prophylactic or therapeutic effect.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 035571971

Download citation: RISBibTeXText


Related references

Prophylactic and therapeutic treatment of the ductal epithelium of a mammary gland for cancer. Official Gazette of the United States Patent and Trademark Office Patents 1277(1), 2003

Destruction of the epithelium of an exocrine gland in the prophylactic and therapeutic treatment of cancer. Official Gazette of the United States Patent and Trademark Office Patents 1270(1), 2003

Genetic abnormalities in mammary ductal intraepithelial neoplasia-flat type (clinging ductal carcinoma in situ): A simulator of normal mammary epithelium. Cancer 88(9): 2072-2081, 2000

BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization. Developmental Biology 373(1): 95-106, 2013

Elevation of lactoferrin gene expression in developing, ductal, resting, and regressing parenchymal epithelium of the ruminant mammary gland. Journal of Dairy Science 79(7): 1198-1208, 1996

Key stages in mammary gland development - the alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium. Breast Cancer Research 8(2): 207, 2006

Quantitative morphometric differences between ductal and lobular cancer of the mammary gland. Mediko-Biologichni Problemi 16: 138-146, 1988

Examining the pathogenesis of breast cancer using a novel agent-based model of mammary ductal epithelium dynamics. Plos one 8(5): E64091, 2013

Mitotic activity of the mammary gland epithelium of mice after the excision of a considerable part of the mammary gland tissue.. Byull. eksp. Biol. Med 54(12): 84-89, 1962

Inactivation of VEGF in mammary gland epithelium severely compromises mammary gland development and function. Faseb Journal 21(14): 3994-4004, 2007

A spontaneously occurring mammary gland ductal carcinoma in situ in a rhesus macaque (Macaca mulatta) and a review of spontaneous mammary gland tumors in rhesus monkeys. Journal of Medical Primatology 30(2): 121-126, 2001

Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts. Breast Cancer Research 12(2): 202, 2010

Transgenic mice overexpressing tgf alpha exhibit impeded ductal morphogenesis in the mammary gland and ductal metaplasia in the pancreas. Journal of Cellular Biochemistry Suppl. (14 Part E): 79, 1990

Mammary gland cell culture and preliminary analysis of mammary gland epithelium. Journal of the Chinese Society of Veterinary Science 15(1): 53-62, 1989

Genetic control of ductal morphology, estrogen-induced ductal growth, and gene expression in female mouse mammary gland. Endocrinology 155(8): 3025-3035, 2014