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Structure of skeletal troponin-C in complex with skeletal troponin-I115-131 Comparison to cardiac troponin-C-troponin-I147-163 complex






Biophysical Journal 78(1 Part 2): 434A

Structure of skeletal troponin-C in complex with skeletal troponin-I115-131 Comparison to cardiac troponin-C-troponin-I147-163 complex



Accession: 035780619



Related references

Heller, W.T.; Abusamhadneh, E.; Finley, N.; Rosevear, P.R.; Trewhella, J., 2002: The solution structure of a cardiac troponin C-troponin I-troponin T complex shows a somewhat compact troponin C interacting with an extended troponin I-troponin T component. We have investigated the structure of the cTnC-cTnI-cTnT(198-298) calcium-saturated, ternary cardiac troponin complex by small-angle scattering with contrast variation. Shape restoration was also applied to the scattering information resulting fro...

Heller, W.T.; Abusamhadneh, E.; Finley, N., 2002: The Solution Structure of a Cardiac Troponin C-Troponin I-Troponin T Complex Shows a Somewhat Compact Troponin C Interacting with an Extended Troponin I-Troponin T Component. We have investigated the structure of the cTnC-cTnI-cTnT(198-298) calcium-saturated, ternary cardiac troponin complex by small-angle scattering with contrast variation. Shape restoration was also applied to the scattering information resulting fro...

Leszyk, J.; Collins, J.H.; Leavis, P.C.; Tao, T., 1988: Cross-linking of rabbit skeletal muscle troponin subunits: labeling of cysteine-98 of troponin C with 4-maleimidobenzophenone and analysis of products formed in the binary complex with troponin T and the ternary complex with troponins I and T. The sulfhydryl-specific, heterobifunctional, photoactivatable cross-linker 4-maleimidobenzophenone (BPMal) was used to study the interaction of rabbit skeletal muscle troponin subunits TnC, TnT, and TnI. TnC was labeled at Cys-98 by the maleimide...

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Saijo, Y.; Takeda, S.; Scherer, A.; Kobayashi, T.; Maéda, Y.; Taniguchi, H.; Yao, M.; Wakatsuki, S., 1997: Production, crystallization, and preliminary X-ray analysis of rabbit skeletal muscle troponin complex consisting of troponin C and fragment (1-47) of troponin I. Troponin is a ternary protein complex consisting of subunits TnC, TnI, and TnT, and plays a key role in calcium regulation of the skeletal and cardiac muscle contraction. In the present study, a partial complex (CI47) was prepared from Escherichia...

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