EurekaMag Full Text Articles Chapter 35,791

Zhyllaiev, G.G. 1999: Subpopulational structure of natural and anthropogenically transformed populations qf Soldanella hungarica Simonk in the Carpathians. Ukrayins'Kyi Botanichnyi Zhurnal. 56(6): 638-642

Strony, R.; Perlman, J.; Neely, C.; Stewart, B.; Dare, J.; Gerhart, J.; George Weinstein, M. 2003: Subpopulations of NeuroM and MyoD positive cells in the chick embryo epiblast. FASEB Journal 17(4-5): Abstract 467

Lincoln, J.; Shotton, H.R. 2001: Subpopulations of enteric nerves respond differently to treatments of diabetic neuropathy. Diabetes 50(Suppl 2): A187

Dmitrieva, N.; Marshall, N.; Keyser, K.T.; Curcio, C.A. 1999: Subpopulations of human blue cones identified by immunocytochemistry for calcium-binding proteins. IOVS Investigative Ophthalmology and Visual Science 40(4): S158

Hyink, D.P.; Wilson, P.D.; Snoeck, H.; Burrow, C.R. 1999: Subpopulations of human fetal renal mesenchymal cells defined by flow cytometry. Journal of the American Society of Nephrology 10(Program and Abstr. Issue): 405A

Miller, M.K.; Dmitrieva, N.; Curcio, C.A.; Keyser, K.T. 1999: Subpopulations of human red and green cones identified by differential expression of calcium-binding proteins. Society for Neuroscience Abstracts 25(1-2): 139

Klemens, A.; Sturm, C.; Menauer, F.; Grevers, G. 2000: Subpopulations of leukocytes in the nasal mucosa of patients with chronic sinusitis. European Archives of Oto-Rhino-Laryngology 257(2): 91

Zoch Zwierz, W.; Wiercinski, R.; Stasiak Barmuta, A.; Wasilewska, A.; Winiecka, W.; Tomaszewska, B. 1999: Subpopulations of lymphocytes of peripheral blood in children with submicroscopic and mesangial proliferative glomerulonephritis. Pediatric Nephrology 13(7): C58

Kempf, J.; Victor, T. 2003: Subpopulations of metabolic syndrome in the general population. Diabetes and Metabolism 29(Hors serie 2): 4S32-4S33

Deptula, W.; Tokarz Deptula, B. 2000: Subpopulations of peripheral blood lymphocytes in rabbits, experimentally infected with various dose of VHD virus, polish starin Kr-1. Immunology Letters 73(2-3): 160-161

Embrey, M. 2003: Subpopulations susceptible to waterborne diseases are surprisingly diverse. Journal - American Water Works Association 95(3): 34-37

Pelaez, L.I.; Manriquez, M.C.; Nath, K.A.; Romero, J.C.; Juncos, L.A. 2003: Subpressor angiotensin II infusion enhances the hypertensive response to simple stress without causing sustained hypertension in unrestrained rats. FASEB Journal 17(4-5): Abstract 805

Bursztyn, M.; Mekler, J. 2000: Subpressor dose of L-NAME unmasks hypertensive effects of insulin. American Journal of Hypertension 13(4 Part 2): 82A

Wienkoop, S.; Glinski, M.; Weckwert, W. 2003: Subproteomics at a single cell level Active pathways in Arabidopsis thaliana trichomes. Molecular and Cellular Proteomics 2(7 Suppl): S41

Genest, D.R.; Krane, J.; Kostopoulou, E.; Lee, K.R.; Hogan, C.; Bellerose, B.; Sun, D.; Crum, C.P. 2000: Subqualifying ASCUS Comparisons of observer vs laboratory data in predicting high risk HPV and an abnormal follow-up. Laboratory Investigation 80(1): 35A

Liang, L.P.; Roberts, L.J.; Patel, M.N. 2001: Subregion-specific increase in hippocampal F2-isoprostane formation after kainate administration. Epilepsia 42(Suppl 7): 130

Hirsch, D.; Lowry, C.A.; Plant, A.; Lightman, S.L. 1999: Subregional analysis of the effects of corticotropin-releasing factor on serotonin transporter mRNA expression within mesostriatal and mesolimbocortical serotonergic systems. Society for Neuroscience Abstracts 25(1-2): 74

Franck, H.; Gottwalt, J.; Welcker, M. 2003: Subregional bone mineral density measurements of the hand in patients with rheumatoid arthritis and controls. Calcified Tissue International 72(4): 416-417

Pehek, E.A.; Pluto, C.P. 1999: Subregional effects of the catecholamine uptake blocker nomifensine in subregions of the rat prefrontal cortex. Society for Neuroscience Abstracts 25(1-2): 1963

Pei, J.; Marrano, P.; Beheshti, B.; Lim, G.; Fabricius, N.; Burgetz, I.; Squire, J.A.; Zielenska, M. 2002: Subregional mapping gene amplification at chromosome band 17p11-13 by CGH array analysis in osteosarcoma. Proceedings of the American Association for Cancer Research 43: 297

Lim, Gloria; Al Romaih, Khaldoun; Karaskova, Jana; Bayani, Jane; Vukovic, Bisera; Squire, Jeremy A.; Zielenska, Maria 2003: Subregional mapping of recurrent chromosomal SKY breakpoints by m-BAND analysis provides a more precise localization of complex translocation breakpoints in osteosarcoma. Proceedings of the American Association for Cancer Research 44: 51

Fagergren, P.S.; Smith, H.R.; Daunais, J.B.; Nader, M.A.; Porrino, L.J.; Hurd, Y.L. 2002: Subregional upregulation of prodynorphin mRNA expression in the primate striatum after high, but not low, dose cocaine self-administration. Drug and Alcohol Dependence 66(Suppl 1): S53

George, A.E.; Biswas, J.; Agarwal, R.; Kumarasamy, N.; Solomon, S. 1999: Subretinal cysticercosis in a patient with AIDS: treatment with xenon arc photocoagulation. Retina 19(5): 467-468

Schwartz, S.G.; Lee, C.M. 1999: Subretinal fibrosis and diabetic macular edema. IOVS Investigative Ophthalmology and Visual Science 40(4): S306

Kuo, I.C.; Rao, N.A.; Johnston, R.; Margolis, T.P.; Nozik, R.A.; Cunningham, E.T. 1999: Subretinal fibrosis as a long-term complication of Vogt-Koyanagi-Harada syndrome. IOVS Investigative Ophthalmology and Visual Science 40(4): S383

Alrawi, A.M.; Wald, K.J. 1999: Subretinal fibrosis associated with diabetic tractional retinal detachments. IOVS Investigative Ophthalmology and Visual Science 40(4): S950

Quintyn, J.-C.; Brasseur, G. 2004: Subretinal fluid in primary rhegmatogenous retinal detachment: physiopathology and composition. Survey of Ophthalmology 49(1): 96-108

Yilmaz, G.; Acar, M.; Unlu, N.; Kocaoglan, H.; Duman, S.; Aydin, P. 2000: Subretinal fluid nitric oxide levels in patients with proliferative vitreoretinopathy. IOVS Investigative Ophthalmology and Visual Science 41(4): S348

Johnson, T.M.; Elner, S.; Johnson, M.W.; Schneiderman, T.; Perkovich, P.T. 2000: Subretinal gas migration through optic disc pits Clinical insights into pathogenesis. IOVS Investigative Ophthalmology and Visual Science 41(4): S755

Beck, A.P.; Ravage, Z.B.; Richmond, C.A.; Jampol, L.M. 2004: Subretinal hemorrhage associated with cytomegalovirus retinitis in a patient without concurrent thrombocytopenia. Retina 24(4): 611-613

Fritsche, P.L.; Flipsen, E.; Polak, B.C. 2000: Subretinal hemorrhage from retinal arterial macroaneurysm simulating malignancy. Archives of Ophthalmology 118(12): 1704-1705

Sachs, H.G.; Kobuch, K.; Koehler, M.; Schwahn, H.N.; Gekeler, F.E.; Jakob, W.; Marienhagen, J.; Zrenner, E.; Gabel, V.P. 2000: Subretinal implantation of electrodes for acute in vivo stimulation of the retina to evoke cortical responses in minipig. IOVS Investigative Ophthalmology and Visual Science 41(4): S102

Rosenfeld, P.J.; Merritt, J.; Hernandez, E.; Meller, D.; Rosa, R.H.Jr; Tseng, S.C.G. 1999: Subretinal implantation of human amniotic membrane A rabbit model for the replacement of Bruchs membrane during submacular surgery. IOVS Investigative Ophthalmology and Visual Science 40(4): S206

Leys, A.M.; Cohen, S.Y. 2002: Subretinal leakage in myopic eyes with a posterior staphyloma or tilted disk syndrome. Retina 22(5): 659-665

Shah, G.K.; Fischer, D.; Fineman, M.S.; Sharma, S.; Maguire, J. 1999: Subretinal neovascularization secondary to Candida endophthalmitis: long-term follow-up after submacular surgery. Retina 19(1): 81-82

Kobuch, K.A.; Gekeler, F.; Schwahn, H.; Zrenner, E.; Gabel, V.P.; Retina Implant Project Germany 2001: Subretinal stimulation of the rabbit retina with electrode foils Surgical technique and histological assessment. IOVS Investigative Ophthalmology and Visual Science 42(4): S815

Schatzki, T.F.; Toyofuku, N. 2002: Subsample preparation of pistachios. Mycopathologia 155(1-2): 43

Paine, M.D.; Allard, P.J.; Mann, G.A. 1999: Subsampling in sediment quality assessments Why bother?. Canadian Technical Report of Fisheries and Aquatic Sciences 2293: 52-53

Lesnefsky, E.J.; Slabe, T.J.; Stoll, M.S.K.; Hoppel, C.L. 2000: Subsarcolemmal mitochondria are the site of cardiolipin depletion and cytochrome c loss during myocardial ischemia. Circulation 102(18): 2; 78

Lipp, P.; Mackenzie, L.; Laine, M.; Berridge, M.J.; Bootman, M.D. 2001: Subsarcolemmal recruitment of InsP3-receptor induced Ca2+ sparks underlies the potency of endothelin-1 to induce cardiac arrhythmia. Pfluegers Archiv European Journal of Physiology 441(6 Suppl): R152

Osborne, J.L.; Nelson, M.; Enscore, D.J.; Yum, S.I.; Gale, R.M. 2000: Subsaturated nicotine transdermal therapeutic system. Official Gazette of the United States Patent and Trademark Office Patents 1241(4)

Marchaland, J.P.; Bures, C.; Versier, G.; Des Deserts, M.D.; Rigal, S. 2003: Subscapularis approach in Bristow, Latarjet procedure Retrospective study of 70 cases. Science and Sports 18(2): 86-92

Zigiotti, G.L.; Meduri, R.A.; Scorolli, L.; Della Valle, V.; Morara, M.; Ricci, R.; Scorolli, L.; Scalinci, S.Z.; Perrone, M. 2001: Subscleral adipocytes implantation in retinitis pigmentosa. IOVS Investigative Ophthalmology and Visual Science 42(4): S75

Essenpreis, M.; Gerber, M.T.; Hansen, M.V.; Cronrath, C.M. 2002: Subscription based monitoring system and method. Official Gazette of the United States Patent and Trademark Office Patents 1260(1)

Spears, J.R.; Prcevski, P.; Jiang, A.J.; Wu, X.; Spanta, A.; Henney, C.; Crilly, R.J.; Vanderheide, R. 1999: Subselective intracoronary aqueous oxygen hyperoxemic reperfusion after one hour coronary occlusion in swine restores left ventricular function. Journal of the American College of Cardiology 33(2 Suppl A): 357A

Fleming, W.; Molnar, L.; Taylor, D. 1999: Subsensitivity of cerebellar purkinje neurons of genetically epileptic rats to GABAA receptor agonists in slices. FASEB Journal 13(4 Part 1): A475

Ansell, S.M.; Schilder, R.J.; Pieslor, P.C.; Gordon, L.I.; Emmanouilides, C.; Czuczman, M.S.; Wang, H.; Witzig, T.E.; Saville, M.W.; Molina, A. 2003: Subsequent antilymphoma therapies are feasible after radioimmunotherapy with 90Y ibritumomab tiuxetan. Blood 102(11): 308b

Ansell, S.M.; Ristow, K.M.; Habermann, T.M.; Wiseman, G.A.; Witzig, T.E. 2001: Subsequent chemotherapy regimens are well tolerated after radioimmunotherapy with ZevalinTM for non-Hodgkin lymphoma. Blood 98(11 Part 1): 604a-605a

Choi, D.; Qiu, C.; Weitzner, R.; Westbrook, H.; Malinow, A. 1999: Subsequent epidural injection of lidocaine extends rostral anesthetic level after intrathecal fentanyl but not bupivacaine/fentanyl. Anesthesiology 91(3A): A854

Hirayama, A.; Kodama, K.; Uematsu, M.; Kondo, N.; Ueda, Y.; Mizuno, Y.; Higuchi, Y. 1999: Subsequent left ventricular dilatation after myocardial infarction can be predicted by plasma brain natriuretic level independent of infarct-related artery patency. Circulation 100(18): 1; 578

Hirayama, A.; Kodama, K.; Mizuno, Y.; Kashiwase, K.; Shimizu, M.; Otani, T. 2000: Subsequent left ventricular dilatation after myocardial infarction can be predicted by plasma brain natriuretic peptide level with or without restenosis. European Heart Journal 21(Abstract Suppl): 74

Wheatley, D.A.; Vini, L.; A'hern; Harmer, C. 2001: Subsequent malignancies in patients treated for differentiated thyroid cancer. British Journal of Cancer 85(Suppl 1): 69

Lucas, C.; Cordonnier, C.; Mackowiak, M.A.; Leys, D. 2003: Subsequent migraine attacks efficiently treated with zolmitriptan revealing a carotid artery dissection. Cephalalgia 23(7): 670-671

Sliwa, K.; Zhanje, F.; Essop, R.M. 2001: Subsequent pregnancy in patients with documented peripartum cardiomyopathy A prospective echocardiographic and cytokine evaluation. Circulation 104(17): 2; 659

Mckinney, E.T.; Haddad, B.; Barton, J.R.; Livingston, J.C.; Sibai, B.M. 2001: Subsequent pregnancy outcomes in women with a history of HELLP syndrome ltoreq 30 weeks. American Journal of Obstetrics and Gynecology 184(1): S79

Okines, A.F.C.; Radstone, C.R.; Thomson, C.; Hayward, C.E.; Hancock, H.; Hancock, B.W. 2002: Subsequent primary cancers after treatment for Hodgkins Disease and Non-Hodgkins Lymphoma. British Journal of Cancer 86(Suppl 1): S41

Gould, W.R.; Tracy, P.B. 2002: Subsequent to Endocytosis from Plasma, Factor V Is O-Glycosylated and Proteolytically Cleaved at a Unique Site Modifications That Produce a Distinct, yet Functional Platelet-Derived Cofactor. Blood 100(11): Abstract No. 469

Guarriello, A.; Curatolo, C.; Ludovico, G.M.; Maselli, F.P.; De Rienzo, G.; Pagliarulo, A. 1999: Subsequent urethral relapses with extension into the corpora cavernosa of embryonal rhabdomyosarcoma of the prostate. Journal of Urology 161(6): 1911

Petyaev, A.M.; Petyaev, I.M. 2000: Subsequent use of protein A and protein L for the study of the content, distribution and composition of anti-lipoprotein immune complexes in patients with atherosclerosis. Journal of Submicroscopic Cytology and Pathology 32(3): 477

Langsley, G. 2000: Subservion of host cell-lymphocyte signaling by Theileria parasites. Memorias do Instituto Oswaldo Cruz 95(Suppl 2): 25-26

Baerlocher, G.M.; Sloand, E.M.; Alter, B.P.; Wagner, J.E.; Vulto, I.M.; Leathwood, L.; Young, N.S.; Lansdorp, P.M. 2002: Subset Specific Telomere Length To Distinguish Patients with Bone Marrow Failure Syndromes?. Blood 100(11): Abstract No. 863

Mobley, J.L.; Spencer, N.F.L.; Raynor, M. 2000: Subset-specific migration of CD4 T cells into the lungs of ovalbumin-challenged mice. FASEB Journal 14(6): A1147

Meldgaard Knudsen, L.; Jensen, L.; Jarlbaek, L.; Hansen, P.G.; Hansen, S.W.; Drivsholm, L.; Nikolaisen, K.; Gaarsdal, E.; Johnsen, H.E. 1999: Subsets of CD34+ hematopoietic progenitors and platelet recovery after high dose chemotherapy and peripheral blood stem cell transplantation. Haematologica 84(6): 517-524

Jonasson, L.; Wikby, A.; Tompa, A. 2002: Subsets of CD8+ T cells are expanded in stable coronary artery disease. Journal of the American College of Cardiology 39(5 Suppl A): 297A

Kisicki, M.; Piacentini, J. 2002: Subsets of child obsessive-compulsive disorder based on gender and age of onset. Journal of Investigative Medicine 50(1): 16A

Sunderkoetter, C.; Leenen, P.; Nikolic, T.; Ehrchen, J.; Sindrilaru, A.; Drevets, D. 2004: Subsets of murine blood monocytes in infection. Archives of Dermatological Research 295(8-9): 341

Kasymov, S.; Kasymov, B. 2000: Subsidiary support of the detoxic function of liver and quantitative genotherapy. International Journal of Artificial Organs 23(8): 567

Fukui, D.; Murakami, M.; Nakano, S. 2001: Subsidized effect of aquatic insects on bat foraging Verification using the manipulative field experiment. Bat Research News 42(3): 99

Meyers, A.; Cutts, D.; Frank, D.A.; Levenson, S.; Skalicky, A.; Cook, J.; Berkowitz, C.; Black, M.; Casey, P.; Zaldivar, N. 2003: Subsidized housing and child nutritional status Data from a multisite surveillance Study. Pediatric Research 53(4 Part 2): 579A

Meyers, A.; Frank, D.A.; Cook, J.T.; Cutts, D.; Berkowitz, C.; Black, M.; Casey, P.; Zaldivar, N.; Levenson, S.; C Snap Study Group 2001: Subsidized housing, food security, and growth among families with children Data from a multisite surveillance study. Pediatric Research 49(4 Part 2): 465A

Liel, Y.; Castel, H.; Bonneh, D.Y. 2002: Subsidizing medications does not ensure the use of potent osteoporosis drugs following low-impact fractures. Journal of Bone and Mineral Research 17(Suppl 1): S479

Feher, I.; Virag, G.; Zsarnoczai, S.J.; Salem, H.F.; Villanyi, L. 2003: Subsidy for private storing butter and cream in Hungary. Journal of Dairy Science 86(Suppl 1): 72

Power, M.E. 2001: Subsidy theory and Gary Polis contributions to the synthesis of food web and landscape ecology. AAAS Annual Meeting and Science Innovation Exposition 167: A32, February 15-20

Danubio, M.E.; Coppa, A.; Gruppioni, G. 2002: Subsistence patterns and seasonality of vital events in historical times in Central Apennines. American Journal of Physical Anthropology Suppl (34): 60

Malet, C.; Chichlo, B.; Robert Lamblin, J.; Hladik, C.M.; Pasquet, P. 2003: Subsistence patterns, food perception and preferences among indigenous people of Arctic Yakutia. Bulletins et Memoires de la Societe d'Anthropologie de Paris 15(1-2): 101-120

Yazaki, T.; Ohnishi, M. 2000: Subsite structure of beta-glucosidase from Aspergillus niger and kinetic mechanism of the beta-glucosidase-catalyzed reactions. Ohnishi, Masatake Author Glycoenzymes 171-187

Jester, W.R.; Schultheis, J.R.; Adams, D.E.; Taylor, B. 2000: Subsoiling and its effects on root yield and quality of Beauregard. HortScience 35(4): 569-570

Painter, M.J.; Capute, A.; Accardo, P. 2001: Subspecialization in the care of children with neurodevelopmental disabilities. Journal of Child Neurology 16(2): 131-133

Smaldone, A. 2003: Subspecialty health care and incidence of childhood ketoacidosis. Diabetes 52(Suppl 1): A43-A44

Bernacki, R.; Kwok, Y.; Kim, C. 2002: Subspecialty selection Is there a correlation between supply and demand?. Journal of Investigative Medicine 50(1): 46A

Frith, C.B.; Frith, D.W. 1999: Subspeciation in the Australian-endemic Great Bowerbird Chlamydera nuchalis a review and revision. Bulletin Of The British Ornithologists' Club. 119(3): 177-189,.

Liu Nai, F. Huang, Z.H.; Wen Long Ying 2004: Subspecies divergence of przewalski s rock partridge description of a new subspecies. Acta Zootaxonomica Sinica 29(3): 600-605

Miller,M.P.; Haig,S.M.; Gratto-Trevor,C.L.; Mullins,T.D. 2010: Subspecies status and population genetic structure in Piping Plover. Auk 7(1): 57-71

Farkac, J.; Fassati, M. 1999: Subspecific taxonomy of Leistus montanus from Central Europe. Acta Societatis Zoologicae Bohemicae 63(4): 407-425

Masterson, T.J. 2003: Subspecific variation in the crania of Cebus capucinus. American Journal of Physical Anthropology Suppl (36): 147

Miller, R.B.; Leslie, S.T.; Malkowska, S.T. Antoinette; Prater, D.A.; Knott, T.J.; Heafield, J.; Challis, D. 1999: Substained release compositions and a method of preparing pharmaceutical compositions. Official Gazette of the United States Patent and Trademark Office Patents 1227(2)

Takada, S.; Nakagawa, Y.; Iwasa, S. 2000: Substained release microcapsule of physiologically active compound which is slightly water soluble at pH 6 to 8. Official Gazette of the United States Patent and Trademark Office Patents 1238(1)

Carpenter, K.M.; Miele, G.M.; Hasin, D.S.; Blaine, J. 2000: Substance Dependence Severity Scale Reliability and validity of ICD-10 substance use disorders. Drug and Alcohol Dependence 60(Suppl 1): S32-S33, 1 December

Kitano, S.; Sasaki, T.; Yoshida, K.; Otani, T.; Yu, L.; Wu, Y.; Katsunuma, N. 1999: Substance FA-70D, process for producing the same, and uses thereof. Official Gazette of the United States Patent and Trademark Office Patents 1223(4)

Pothoulakis, C.; Valenick, L.; Castagliuolo, I.; Akbarali, H.; Israel, B. 1999: Substance P -induced cell proliferation and focal adhesion kinase activation requires epidermal growth factor receptor tyrosine kinase activity. Gastroenterology 116(4 Part 2): A637

Leeman, S.E.; Ferguson, S.L. 2000: Substance P: an historical perspective. Neuropeptides 34(5): 249-254

Liu, J.; Castagliuolo, I.; Keates, A.; Pothoulakis, C. 2000: Substance P Induced interleukin-8 gene upregulation involves AP-1 and NF-kappaB-dependent pathways. Gastroenterology 118(4 Suppl 2 Pt 1): AGA A564

Datar, P.; Srivastava, S.; Coutinho, E.; Govil, G. 2004: Substance P: structure, function, and therapeutics. Current Topics in Medicinal Chemistry 4(1): 75-103

Mackinnon, A.C.; Armstrong, R.A.; Waters, C.M.; Cummings, J.; Smyth, J.F.; Haslett, C.; Sethi, T. 1999: Substance P activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism. British Journal of Cancer 80(7): 1026-1034

Mackinnon, A.C.; Waters, C.; Sethi, T. 1999: Substance P activates JNK via an oxidant dependent mechanism. British Journal of Cancer 80(Suppl 2): 22

Echtenacher, B.; Hueltner, L.; Maennel, D.N. 2000: Substance P activates innate host defense against bacterial peritonitis Dependence on TNF and mast cells. Scandinavian Journal of Immunology 51(Suppl 1): 87

Fastje, C.D.; Hyde, J.D.; Goot, B.; Meigs, E.; Sun, N.N.; Wong, S.S.; Witten, M.L. 2004: Substance P agonist attenuates pulmonary injury induced through exposure to A/Hong Kong/8/68 influenza virus and JP-8 jet fuel. FASEB Journal 18(4-5): Abstract 335

Lampson, L.A.; Mccluskey, L.P. 2002: Substance P amplifies ability of gamma interferon to increase T-cell entry to brainstem. Neurology 58(7 Suppl 3): A445-A446

Burman, A.C.; Prasad, S.; Mukherjee, R.; Jaggi, M.; Singh, A.T. 2003: Substance P analogs for the treatment of cancer. Official Gazette of the United States Patent and Trademark Office Patents 1272(4)

Hu, B.; Young, E.; Goldman, J.; Hu, H.; Kajander, K. 1999: Substance P and Protein Gene Product 95 labeling of nerve fibers in maxillary sinus mucosa during sinusitis in rabbits. Society for Neuroscience Abstracts 25(1-2): 961

Lieb, K.; Herpfer, I.; Fiebich, B.L.; Berger, M. 2003: Substance P and substance P antagonists in the pathology and treatment of affective disorders. Pharmacopsychiatry 36(5): 244

Stahl, S.M. 1999: Substance P and the neurokinins: novel peptide neurotransmitters in psychopharmacology. Journal of Clinical Psychiatry 60(2): 77-78

Breton, L.; Pineau, N. 2000: Substance P antagonists comprising rosaceae plant extracts. Official Gazette of the United States Patent and Trademark Office Patents 1240(2)

Rasley, A.; Anguita, J.; Marriott, I. 2003: Substance P augments B burgdorferi induced PGE2 production by murine microglia. FASEB Journal 17(7): C16

Michael Titus, A.T.; Whelpton, R.; Blackburn, D.M. 1999: Substance P binding in striatal slices Interaction with substance P fragments. British Journal of Pharmacology 126(Proceedings Suppl ): 113P

Nyberg, F. 2002: Substance P conversion to bioactive fragments An important pathway for the neuromodulatory effect of the undecapeptide. Journal of Peptide Science 8(Suppl): S70

Boeckmann, S.; Seep, J.; Jonas, L. 1999: Substance P delays apoptosis of human polymorphonuclear neutrophils. European Journal of Cell Biology 78(Suppl 49): 29

Kombian, S.B.; Ananthalakshmi, K.V.V.; Narayanan, P.; Matowe, W.C. 2002: Substance P depresses evoked excitatory postsynaptic currents in the rat nucleus accumbens in vitro. Pfluegers Archiv European Journal of Physiology 443(Suppl 1): S211

Nishida, T.; Chikama, T.I.; Nakamura, M. 1999: Substance P derived peptide and IGF-1 eye drops for the treatment of neurotrophic keratopathy. Brain Research 848(1-2): A38

Guo, C.J.; Douglas, S.D.; Lai, J.P.; Li, Y.; Tan, N.; Riedel, E.; Campbell, D.E.; Ho, W.Z. 2003: Substance P enhances HIV infection of human T lymphocytes. Journal of Leukocyte Biology Suppl: 29-30

Tu, S.; Debski, E.A. 1999: Substance P expression in adult optic tectum is regulated by cholinergic input from the nucleus isthmi. Society for Neuroscience Abstracts 25(1-2): 1769

Liu, H.; Mazarati, A.M.; Katsumori, H.; Sankar, R.; Wasterlain, C.G. 1999: Substance P facilitates status epilepticus while SP receptor antagonists block the initiation and the maintenance of status epilepticus. Epilepsia 40(Suppl 2): 113

Yamada, N.; Yanai, R.; Nishida, T.; Inui, M. 2004: Substance P functions as a modulator of corneal epithelial migration through activation of calmodulin-dependent protein kinase II. Journal of Pharmacological Sciences 94(Suppl 1): 78P

Hunt, S.P.; Morcuende, S.; Moss, A.; Peters, M.; Giese, K.P.; Felipe, C.D.E.; Gadd, C. 2003: Substance P in depression and addiction. Journal of Neurochemistry 87(Suppl 1): 19

Ebner, K.; Saria, A.; Singewald, N. 2003: Substance P in the medial amygdala Emotional stress-sensitive release and modulation of anxiety-related behaviour. Naunyn-Schmiedeberg's Archives of Pharmacology 367(Suppl 1): R85

Santoni, G.; Spreghini, E.; Lucciarini, R.; Staffolani, M.; Pompei, P.; Piccoli, M. 1999: Substance P in vivo administration affects thymocyte differentiation pathways Role of substance P in the capsaicin-induced apoptosis. Brain Research 848(1-2): A33

Okabe, T.; Hide, M.; Morita, E.; Yamamoto, S. 2000: Substance P induced LTB4 release from mouse bone marrow derived mast cells via p42 MAP kinase. Journal of Dermatological Science 23(3): 205

Mackinnon, A.; Waters, C.; Sethi, T. 1999: Substance P induces apoptosis in SCLC cells via the generation of ROS. British Journal of Cancer 80(Suppl 2): 44

Koch, H.; Van Drongelen, W.; Marcuccilli, C.J.; Hecox, K.E.; Ramirez, J.M.rino 2002: Substance P induces bursting in neocortical neurons recorded in slice preparations of mice. Epilepsia 43(Suppl 7): 5-6

Wang, X.E.; Watanabe, S.; Hirose, M.; Oide, H.; Itatsu, T.; Osada, T.; Kitamura, T.; Ikejma, K.; Miyazaki, A.; Takei, Y.; Ogawa, K.; Sato, N. 1999: Substance P induces migration and proliferation of cultured rat stellate cells with the modulation of cytoskeletal system. Gastroenterology 116(4 Part 2): A1287

Rall, G.F.; Patterson, C.E.; Daley, J.K.; Makhortova, N. 2003: Substance P inhibition of measles virus spread in neurons. Journal of Neurovirology 9(Suppl 3): 51-52

Zhu, J.P.Q.; Cadet, J.L.; Angulo, J.A. 2003: Substance P involvement in methamphetamine-induced cell death of striatal neurons. Journal of Neurochemistry 87(Suppl 1): 70

Dimitrijevich, S.D.; Henderson, K.; Moeller, M. 2000: Substance P is a mediator of corneal neurogenic inflammation. IOVS Investigative Ophthalmology and Visual Science 41(4): S904

Mcdermott, A.M.; Bentley, E.; Marfurt, C.F.; Jones, M.A.; Murphy, C.J. 1999: Substance P is increased in the corneal epithelium from dogs with chronic epithelial erosions. IOVS Investigative Ophthalmology and Visual Science 40(4): S337

Lubahn, C.; Almond, S.; Zhu, Y.; Hoffman, S.; Lorton, D. 1999: Substance P levels are altered in lymphoid organs in autoimmune prone mice. Society for Neuroscience Abstracts 25(1-2): 942

Kraft, M.; Noailles, P.; Angulo, J.A. 2001: Substance P modulates cocaine-evoked dopamine overflow in the striatum of the rat brain. Annals of the new York Academy of Sciences 937: 121-131

Svensson, E.; Parker, D.; Grillner, S. 1999: Substance P modulates specific cellular properties in identified motoneurons and CC-interneurons in the lamprey spinal cord. Society for Neuroscience Abstracts 25(1-2): 959

Dean, C.; Seagard, J.L. 1999: Substance P modulation of arterial baroreflexes. Society for Neuroscience Abstracts 25(1-2): 1950

Fong, A.Y.; Potts, J.T. 2004: Substance P modulation of ventral respiratory group neurons. FASEB Journal 18(4-5): Abstract 222

Pothoulakis, C.; Castagliuolo, I.; Morteau, O.; Keates, A.C.; Valenick, L.; Wang, C.C.; Nikulasson, S.; Gerard, C. 1999: Substance P neurokinin-1 receptor mediates different responses in acute versus chronic colitis. Gastroenterology 116(4 Part 2): A799

Wong, T.C.; Wymore, T.W. 2000: Substance P peptides at different membrane mimic interfaces Molecular dynamics simulation study. Biophysical Journal 78(1 Part 2): 323A

Takahama, K.; Tamanaha, Y.; Mochidome, T.; Ishibashi, H. 1999: Substance P potentiation of bradykinin-induced discharges in airway vagal afferents. Japanese Journal of Pharmacology 79(Suppl 1): 37P

Cowan, A.R.; Bago, M.; Dean, C.; Seagard, J.L. 1999: Substance P potentiation of non-NMDA receptor-induced changes in blood pressure. Society for Neuroscience Abstracts 25(1-2): 1950

Abe, K.; Shimoyama, Y.; Yamamoto, S.; Koshihara, Y.; Hirabayashi, K.; Sato, T.; Inoue, H. 2002: Substance P production by synovial fibroblasts from patients with arthritis. Japanese Journal of Pharmacology 88(Suppl 1): 138P

Lee, W.S.; Sohn, I.B. 2003: Substance P prolongs human hair growth in vitro. Journal of Dermatological Science 33(2): 137-138

Kramer, J.H.; Komarov, A.M.; Weglicki, W.B. 2001: Substance P receptor blockade in vivo lowers nitric oxide levels in postischemic Mg-deficient rat hearts. FASEB Journal 15(5): A920

Trunkle, T.; Walters, N.; Pascual, D.W. 2003: Substance P receptor-deficient mice show elevated secretory -IgA responses to oral Salmonella vaccines and increased resistance to wild-type Salmonella challenge. FASEB Journal 17(7): C27

Blum, A.; Metwali, A.; Elliott, D.; Weinstock, J.V. 2002: Substance P regulates T cell IFNgamma production through direct interaction with a substance P receptor expressed on these cells. FASEB Journal 16(4): A722

Weinstock, J.V.; Blum, A.; Metwali, A.; Elliott, D.; Arsenescu, R. 2002: Substance P regulates Th1-type colitis in IL10 KO mice. Gastroenterology 122(4 Suppl 1): A 35

Moriarty, D.V.; O'riordan, A.; O'donoghue, D.P.; Hyland, J.; Sheahan, K.; Baird, A.W. 2000: Substance P release and modulation of human colonic ion transport Alterations during IBD. Gastroenterology 118(4 Suppl 2 Pt 2): AGA A1105

Inoue, A.; Morioka, N.; Kumagai, K.; Takeda, K.; Hide, I.; Nakata, Y. 2000: Substance P release from rat primary afferent neurons. Japanese Journal of Pharmacology 82(Suppl 1): 33P

Harrison, M.B. 1999: Substance P release from striatonigral neurons is differentially regulated by D1 dopaminergic and muscarinic agonists. Society for Neuroscience Abstracts 25(1-2): 2212

Marvizón, J.C.; Grady, E.F.; Stefani, E.; Bunnett, N.W.; Mayer, E.A. 1999: Substance P release in the dorsal horn assessed by receptor internalization: NMDA receptors counteract a tonic inhibition by GABA(B) receptors. European Journal of Neuroscience 11(2): 417-426

Maubach, K.A.; Martin, K.; Smith, D.; Ali, Z.; Seabrook, G.R. 1999: Substance P stimulates GABA-mediated synaptic transmission in the guinea pig basolateral amygdala in vitro. Society for Neuroscience Abstracts 25(1-2): 956

Akaike, N.; Waug, Z.M.; Rhee, J.S. 1999: Substance P suppresses ATP facilitation on spontaneous glycine release from presynaptic nerve terminals. Society for Neuroscience Abstracts 25(1-2): 1190

Witten, M.L.; Harris, D.T. 1999: Substance P treatment for immunostimulation. Official Gazette of the United States Patent and Trademark Office Patents 1225(5)

Lee, C.H.; Whiteman, A.L.; Murphy, C.J.; Barney, N.P.; Taylor, P.B.; Reid, T.W. 2002: Substance P, insulinlike growth factor 1, and surface healing. Archives of Ophthalmology 120(2): 215-217

Nyberg, Fred; Zhou, Qin; Boutros, Milad; Karlsson, Krister; Frandberg, Per Anders; Le Greves, Pierre 1999: Substance P, its converting enzymes and its N-terminal fragment substance P1-7 in opioid dependent rats. Brain Research 848(1-2): A42

Lappi, D.A.; Wiley, R.G. 2000: Substance P-Saporin conjugates and methods of use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1234(3)

Sonea, I.M.; Wannemuehler, M.J.; Weinstock, J.V.; Waters, W.R.; Elliott, D.E.; Harp, J.A. 1999: Substance P-binding sites are increased in T-cell receptor alpha-deficient mice with inflammatory bowel disease. Society for Neuroscience Abstracts 25(1-2): 1559

Sakamoto, H.; Li, Y.; Kawate, T.; Atsumi, S. 2000: Substance P-containing primary afferents contact NK-1 receptor immunoreactive neuronal elements in synaptic glomeruli in the chicken spinal dorsal horn. Neuroscience Research Suppl (24): S111

Ericson, A.C.; Kechagias, S.; Sjostrand, S.E. 1999: Substance P-immunoreactivity in the human gastric mucosa. Society for Neuroscience Abstracts 25(1-2): 940

Coltman, C.; Prince, R.I.; Purcell, W.M.; Osborne, R.H. 2002: Substance P-induced tonic contraction of the rat isolated ileum involves activation of L-type calcium channels and inositol trisphosphate receptors. British Journal of Pharmacology 135(Proceedings Suppl): 234P

Yamada, M.; Ogata, M.; Kawai, M.; Mashima, Y. 2000: Substance P-like immunoreactivity in normal human tears. IOVS Investigative Ophthalmology and Visual Science 41(4): S70

Zhao, D.; Kuhnt Moore, S.; Zeng, H.; Pan, A.; Wu, J.S.; Moyer, M.P.; Pothoulakis, C. 2002: Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves activation of MAP kinases and Rho GTPases. Gastroenterology 122(4 Suppl 1): A-137

Omura, S.; Tomoda, H.; Takahashi, Y. 2003: Substance WK-5344A and wk-5344B and process for producing the same. Official Gazette of the United States Patent and Trademark Office Patents 1266(4)

Katusic, S.K.; Barbaresi, W.J.; Colligan, R.C.; Weaver, A.L.; Mrazek, D.A.; Jacobsen, S.J. 2003: Substance abuse among ADHD cases A population-based birth cohort study. Pediatric Research 53(4 Part 2): 65A

Stuart Van Wormer, Katherine 2001: Substance abuse among Americans of British descent. Straussner, Shulamith Lala Ashenberg Author Ethnocultural factors in substance abuse treatment 167-179

Rothe, E.M.; Ruiz, P. 2001: Substance abuse among Cuban Americans. Straussner, Shulamith Lala Ashenberg Author Ethnocultural factors in substance abuse treatment 97-110

Kwon Ahn, Young Hee 2001: Substance abuse among Korean Americans A sociocultural perspective and framework for intervention. Straussner, Shulamith Lala Ashenberg Ethnocultural factors in substance abuse treatment 418-435

Reid, S.D.; Ramcharan, C.; Ghany, K. 2004: Substance abuse among first admissions to the psychiatric unit of a general hospital in Trinidad. West Indian Medical Journal 53(2): 95-99

Ray, O.S. 2000: Substance abuse and addiction. Neuropsychopharmacology 23(S2): S102-S103

Berridge, V. 2002: Substance abuse and compromise of fathering. Addiction 97(9): 1117; Discussion: 1120-1122

Phillips, J.A.; Nixon, S.J.; Pfefferbaum, B.; Briody, R. 1999: Substance abuse and offense category in female prison inmates. Alcoholism Clinical and Experimental Research 23(5 Suppl): 80A

Kirkpatrick, B.; Messias, E.M.; Tek, C. 2003: Substance abuse and the heterogeneity of schizophrenia a population-based study. Schizophrenia Research 62(3): 293-294

Donahoe, R.M.; Adler, M.W. 2001: Substance abuse and the immune system. Drug and Alcohol Dependence 62(2): 109-110

Rosen, M.I.; Shaner, A.; Rosenheck, R.A. 2002: Substance abuse and the need for money management assistance. Drug and Alcohol Dependence 66(Suppl 1): S150

Wright, E.M. 2001: Substance abuse in African American communities. Straussner, Shulamith Lala Ashenberg Author Ethnocultural factors in substance abuse treatment 31-51

Greydanus, D.E.; Patel, D.R. 2003: Substance abuse in adolescents: a complex conundrum for the clinician. Pediatric Clinics of North America 50(5): 1179-1223

Cregler, L.L. 1999: Substance abuse in sports The impact of cocaine, alcohol, steroids, and other drugs on the heart. Williams, R A The athlete and heart disease: Diagnosis, evaluation and management 131-153

Alvarez, L.R.; Ruiz, P. 2001: Substance abuse in the Mexican American population. Straussner, Shulamith Lala Ashenberg Author Ethnocultural factors in substance abuse treatment 111-136

Matsuyoshi, J. 2001: Substance abuse interventions for Japanese and Japanese American Clients. Straussner, Shulamith Lala Ashenberg Author Ethnocultural factors in substance abuse treatment 393-417

Bromley, M.A.; Sip, S.K.C. 2001: Substance abuse treatment issues with Cambodian Americans. Straussner, Shulamith Lala Ashenberg Author Ethnocultural factors in substance abuse treatment 321-344

Abbott, A.A. 2001: Substance abuse treatment with clients of French background. Straussner, Shulamith Lala Ashenberg Author Ethnocultural factors in substance abuse treatment 180-198

Quail, M.T.; Weimersheimer, P.; Woolf, A.D. 1999: Substance abuse using Telazol An animal tranquilizer. Journal of Toxicology. Clinical Toxicology 37(5): 652

Brust, J.C. 1999: Substance abuse, neurobiology, and ideology. Archives of Neurology 56(12): 1528-1531

Blanchard, K.A.; Bynoe, F.E.; Mourad, M.R.; Morgenstern, J.; Mcveigh, K.H.; Mccrady, B.S.; Irwin, T.W. 2002: Substance abusing women on welfare Psychiatric comorbidity as a predictor of treatment retention. Alcoholism Clinical and Experimental Research 26(5 Suppl): 69A

Lamb, Peter James Brian 2003: Substance applicator. Official Gazette of the United States Patent and Trademark Office Patents 1268(4)

Takebe, M. 2000: Substance containing health-promoting component and process for the production thereof. Official Gazette of the United States Patent and Trademark Office Patents 1233(1)

Kanauchi, O.; Agata, K. 2001: Substance containing proteins and insoluble dietary fibers derived from the germinated seed of a grass family plant and uses thereof. Official Gazette of the United States Patent and Trademark Office Patents 1250(1)

Calluaud, M.; Yerbury, V. 2000: Substance delivery apparatus. Official Gazette of the United States Patent and Trademark Office Patents 1231(5)

Ray, P.; Bhat, V.D.; Mirzaee, D. 2002: Substance delivery apparatus and a method of delivering a therapeutic substance to an anatomical passageway. Official Gazette of the United States Patent and Trademark Office Patents 1265(3)

Jellie, Hugh Philip 2002: Substance delivery device. Official Gazette of the United States Patent and Trademark Office Patents 1257(4)

Rossin, V.D.; Groenke, G.C.; Bourne, G. 2001: Substance delivery device for use with a procedure performing instrument. Official Gazette of the United States Patent and Trademark Office Patents 1249(4)

Nuttbrock, L.; Rosenblum, A.; Magura, S.; Wallace, J.; Marthol, M.; Farkas, S. 2002: Substance dependence and symptoms of PTSD among female sex workers. Drug and Alcohol Dependence 66(Suppl 1): S131

Miele, G.M.; Carpenter, K.M.; Cockerham, M.S.; Trautman, K.D.; Blaine, J.; Hasin, D.S. 1999: Substance dependence severity scale Reliability and validity of a clinician-administered interview for DSM-IV substance use disorders. Alcoholism Clinical and Experimental Research 23(5 Suppl): 41A

Enoki, T.; Koyama, N.; Ikai, K.; Kato, I. 2004: Substance for inducing apoptosis. Official Gazette of the United States Patent and Trademark Office Patents 1287(2)

Miettenen, T.; Wester, I.; Vanhanen, H. 2003: Substance for lowering high cholesterol level in serum and methods for preparing and using the same. Official Gazette of the United States Patent and Trademark Office Patents 1269(2)

Pan, T.L.; Goto, S.; Chen, C.L. 2002: Substance having steroid-like structure, process for the production thereof and antitumor agents containing the same. Official Gazette of the United States Patent and Trademark Office Patents 1263(3)

Singleton, N.; Farrell, M.; Meltzer, H. 2003: Substance misuse among prisoners in England and Wales. International Review of Psychiatry 15(1-2): 150-152

Kavanagh, D.J.; McGrath, J.; Saunders, J.B.; Dore, G.; Clark, D. 2002: Substance misuse in patients with schizophrenia: epidemiology and management. Drugs 62(5): 743-755

Bodiger, M.; Neumann, R.; Heydenreich, F.; Prein, M. 2004: Substance mixture containing bisphenol A. Official Gazette of the United States Patent and Trademark Office Patents 1285(2)

Kanauchi, O.; Agata, K. 2002: Substance originating in germinating seeds of gramineous plant and containing proteins and insoluble dietary fibers and use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1255(3)

Himmelsbach, P.; Radloff, D. 2004: Substance release device. Official Gazette of the United States Patent and Trademark Office Patents 1280(2)

Werner, E. 2000: Substance suppressing allograft rejection. Official Gazette of the United States Patent and Trademark Office Patents 1238(1)

Soong, Leslie Binshyang 2004: Substance that stop any kind of bleeding within one second for medical, surgical, postsurgical and dental uses. Official Gazette of the United States Patent and Trademark Office Patents 1285(5)

Steiner, C.; Jalan, R. 2003: Substance transport in albumin dialysis. Blood Purification 21(4-5): 360

Blanchard, K.A.; Morgenstern, J.; Morgan, T.J.; Labouvie, E.; Hayaki, J. 2000: Substance type as a predictor of treatment outcome Should we sacrifice generalizeability in exchange for internal validity. Alcoholism Clinical and Experimental Research 24(5 Suppl): 142A

Abudabbeh, N.; Hamid, A. 2001: Substance use among Arabs and Arab Americans. Straussner, Shulamith Lala Ashenberg Ethnocultural Factors in Substance Abuse Treatment 275-290

Moe, E.L.; Goldberg, L.; Elliot, D.L.; Kuehl, K.S.; Mcginnis, W.; Fickes, S. 2001: Substance use among high school athletes Were no angels. Medicine and Science in Sports and Exercise 33(5 Suppl): S72

Ames, G.; Cunradi, C.B.; Moore, R. 2001: Substance use among young adults prior to entering Naval Officer Candidate School. Alcoholism Clinical and Experimental Research 25(5 Suppl A): 151A

Price, R.K.; Risk, N.; Wong, M.; Klingle, R. 2002: Substance use and abuse in Asian Americans Results from three national epidemiologic studies. Drug and Alcohol Dependence 66(Suppl 1): S142

Hall, L.S.; Longabagh, R. 2000: Substance use and depression A dermatoglyphic study of monozygotic twins discordant for sexual orientation. Alcoholism Clinical and Experimental Research 24(5 Suppl): 23A

Pierre, K.L.; Sanchez, J.; Koo, D. 2002: Substance use and other risk factors associated with physical injury among women. Drug and Alcohol Dependence 66(Suppl 1): S139

Gilder, D.A.; Wong, V.; Lau, P.; Garcia Andrade, C.; Vallone, M.; Ehlers, C.L. 1999: Substance use and psychiatric disorders in Mission Indian adults. Alcoholism Clinical and Experimental Research 23(5 Suppl): 130A

Flisher,A.J.; Townsend,L.; Chikobvu,P.; Lombard,C.F.; King,G. 2010: Substance use and psychosocial predictors of high school dropout in Cape Town, South Africa. Journal Of Research On Adolescence: 1, 237-255

Chabrol, H.; Armitage, J. 2002: Substance use and the development of antisocial personality in depressed adolescents. Archives of General Psychiatry 59(7): 665; author reply 665

Quinn, D.; Romero, I. 2000: Substance use disorder Prevalence, detection, and referral for treatment. Journal of Investigative Medicine 48(1): 16A

Calabrese, J.; Shelton, M.; Elhaj, O.; Rapport, D.; Youngstrom, E.; Packer, K.; Sak Jackson, K.; Bilali, S.; Findling, R. 2003: Substance use disorders and their treatment response in dual diagnosis bipolar disorder. European Neuropsychopharmacology 13(Suppl 4): S419-S420

Blanchard, J.J.; Brown, S.A.; Horan, W.P.; Sherwood, A.R. 2000: Substance use disorders in schizophrenia: review, integration, and a proposed model. Clinical Psychology Review 20(2): 207-234

Root, T.L.; Pinheiro, Aéa.Poyastro.; Thornton, L.; Strober, M.; Fernandez-Aranda, F.; Brandt, H.; Crawford, S.; Fichter, M.M.; Halmi, K.A.; Johnson, C.; Kaplan, A.S.; Klump, K.L.; La Via, M.; Mitchell, J.; Woodside, D.Blake.; Rotondo, A.; Berrettini, W.H.; Kaye, W.H.; Bulik, C.M. 2010: Substance use disorders in women with anorexia nervosa. International Journal of Eating Disorders 43(1): 14-21

Roehrs, T.A.; Drake, C.; Roth, T. 2002: Substance use for insomnia Associated daytime symptoms and disability. Alcoholism Clinical and Experimental Research 26(5 Suppl): 128A

Gelhorn, H.L.; Stallings, M.C.; Young, S.E.; Corley, R.P.; Hewitt, J.K.; Crowley, T.J. 2002: Substance use patterns and antisocial behavior in clinical family pedigrees. Drug and Alcohol Dependence 66(Suppl 1): S63

Lombardi, E.L.; Longshore, D. 2002: Substance use treatment experiences of transgendered men and women. Drug and Alcohol Dependence 66(Suppl 1): S105-S106

Chakroun, N.; Doron, J.; Swendsen, J. 2002: Substance use, affective problems and personality traits in women A test of two models of comorbidity. Drug and Alcohol Dependence 66(Suppl 1): S29

Parke, R.D. 2002: Substance-abusing fathers: descriptive, process and methodological perspectives. Addiction 97(9): 1118-1119; Discussion: 1120-1122

Hall, E.A.; Prendergast, M.L.; Campos, M.; Wexler, H.; Melnick, G. 2002: Substance-abusing repeat offenders The link between mental disorders and long-term outcomes. Drug and Alcohol Dependence 66(Suppl 1): S73

Tober, C.; Thimm, F.; May, T.; Wolffgramm, J. 2000: Substance-independent changes of dopaminergic transmission in the striatum of drug-addicted rats. European Journal of Neuroscience 12(Suppl 11): 206

Omura, S.; Tomoda, H.; Masuma, R. 2002: Substances KF-1040 and process for producing of the same. Official Gazette of the United States Patent and Trademark Office Patents 1261(2)

Omura, S.; Tomoda, H.; Masuma, R. 2003: Substances KF-1040T4A,KF-1040T4B, KF-1040T5A, and KF-1040T5B, and process for producing same. Official Gazette of the United States Patent and Trademark Office Patents 1273(3)

Bonnefoy, J.Y.; Gauchat, J.F.CedillaOis 2004: Substances and their uses. Official Gazette of the United States Patent and Trademark Office Patents 1283(1)

Tatsumi, Y.; Sagawa, H.; Ohnogi, H.; Kobayashi, E.; Wu, H.K.; Koyama, N.; Ikai, K.; Kato, I. 2004: Substances capable of inducing apoptosis. Official Gazette of the United States Patent and Trademark Office Patents 1287(4)

Nadachi, Y.; Koga, K.; Mizuno, M. 2003: Substances having antiobese and visceral fat-reducing functions and utilization thereof. Official Gazette of the United States Patent and Trademark Office Patents 1273(2)

Sokol, R.J.; Ager, J.; Martier, S.; Janisse, J. 2000: Substances of abuse A major risk for preterm delivery. American Journal of Obstetrics and Gynecology 182(1 Part 2): S73

Lyakina, M.I. 2004: Substances of plant origin in homeopathic pharmacy Methodology of quality standard formulation. Khimiko-Farmatsevticheskii Zhurnal 38(1): 28-30

Cheunsuang, O.; Morris, R. 2002: Substantia gelatinosa neurones in the lumbar spinal cord are inhibited by NPY in both intact and sciatic nerve-sectioned rats An in vitro electrophysiological study. Journal of Physiology (Cambridge) 543P: 110P-111P

Oyanagi, K.; Yamazaki, M.; Tsuchiya, K.; Ikeda, K. 2000: Substantia nigra in progressive supranuclear palsy, corticobasal degeneration and parkinsonism-dementia complex of Guam Specific pathological features. Brain Pathology 10(4): 525

Trevitt, J.T.; Carlson, B.B.; Nowend, K.L.; Cervone, K.; Salamone, J.D. 1999: Substantia nigra pars reticulata is a very potent site for suppression of lever pressing and locomotion by the D1 antagonist SCH 23390. Society for Neuroscience Abstracts 25(1-2): 1160

Grabinski, J.L.; Wolf, R.C.; Markovic, S.N. 2002: Substantial Neurotoxicity Associated with Ifosfamide-Containing Chemotherapy in Refractory Non-Hodgkins Lymphoma. Blood 100(11): Abstract No. 3078

Iwasaki, Y.; Yamato, H.; Takahashi, T.; Ikeda, K.; Kurosawa, T.; Kurokawa, K.; Fukagawa, M. 2001: Substantial and independent contribution of renal dysfunction on the pathogenesis of adynamic bone disease in rats. Journal of the American Society of Nephrology 12(Program and Abstract Issue): 743A

Mehta, S.; Yusuf, S.; Rupprecht, H.J.; Wittlinger, T.; Flather, M.; Pogue, J.; Cronin, L.; Hunt, D.; Varigos, J.; Keltai, M.; Piegas, L.; Lewis, B.; Joyner, C.; Anand, S.; Luz, M. 2000: Substantial benefit of hirudin compared to heparin among unstable angina patients undergoing early percutaneous coronary intervention. Journal of the American College of Cardiology 35(2 Suppl A): 357A

Ruiz-Silva, M.; Silva, R.M.; Menchaca-Diaz, J.L.; Siqueira, A.F.R.S.; Buzzutti, F.I.; Siliano, P.R.; Tajiki, M.H.; Salomão, R.; Fagundes-Neto, U.; Morais, M.B.; Koh, I.H.J. 2002: Substantial changes in the intestine-derived lymph during bacterial translocation. Transplantation Proceedings 34(3): 1001-1002

Androulakis, N.; Ninio, E.; Tsoukatos, D.C. 2004: Substantial contribution of C160 PAF on the PAF-like bioactivity formed in oxidized LDL. Chemistry and Physics of Lipids 130(1): 36

Binder, L.; Schiel, X.; Binder, C.; Schuettrumpf, S.; Armstrong, V.W.; Hiddemann, W.; Oellerich, M. 1999: Substantial cost savings by individualized aminoglycoside therapy in febrile neutropenic patients with underlying malignant hematologic disorders. Clinical Chemistry and Laboratory Medicine 37(SPEC Suppl ): S304

Drasch, G.; Boese O'reilly, S. 2001: Substantial criteria for the diagnosis of a chronic mercury intoxication A study in a gold mining area in the Philippines. International Journal of Hygiene and Environmental Health 204(4): 268

Salomaa, V.V.; Koukkunen, H.; Ketonen, M.; Immonen Raiha, P.; Kesaniemi, Y.A.tero 2002: Substantial decline in the rates but not in the proportion of sudden coronary deaths in Finland during 1983-1997; the FINAMI study. Circulation 106(19): 2; 751

Bell, B.D. 2004: Substantial declines of Archeys frog in the Coromandel Ranges and implications for the future of other Leiopelma species. New Zealand Journal of Zoology 31(1): 100-101

Santuari, L.; Pradervand, S.; Amiguet-Vercher, A-Maria.; Thomas, Jôme.; Dorcey, E.; Harshman, K.; Xenarios, I.; Juenger, T.E.; Hardtke, C.S. 2010: Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays. Genome Biology 11(1): R4

Jonsson, S.; Skyllberg, U.; Björn, E. 2010: Substantial emission of gaseous monomethylmercury from contaminated water-sediment microcosms. Environmental Science and Technology 44(1): 278-283

Meta, J.; Safaei, A.; Lu, C.S.; Seltzer, M.; Silverman, D.; Gambhir, S.S.; Phelps, M.E.; Valk, P.; Czernin, J. 2001: Substantial impact of FDG-PET on re-staging of lung cancer The referring physicians perspective. Journal of Nuclear Medicine 42(5 Suppl): 150P

Bendixen, H.; Holst, C.; Sorensen, T.I.A.; Bartels, E.M.; Astrup, A. 2003: Substantial increase in prevalence of obesity among young Danish adults between 1987 and 2001. International Journal of Obesity 27(Suppl 1): S128

Morris, K.T.; Pommier, R.F.; Fletcher, W. 2000: Substantial increase in survival of carcinoid patients with hepatic arterial infusion therapy. Cancer Journal 6(2): 100

Haskins, M.; Melniczek, J.; Xu, L.; Weil, M.; O'malley, T.; O'donnell, P.; Knox, V.; Aguirre, G.; Sleeper, M.; Ellinwood, N.M.; Volk, S.; Mazrier, H.; Mango, R.; Zweigle, J.; Wolfe, J.; Ponder, K.P. 2002: Substantial long-term clinical improvement in dogs with mucopolysaccharidosis VII following neonatal retroviral vector-mediated gene therapy. American Journal of Human Genetics 71(4 Suppl): 164

Svarstad, E.; Myking, O.; Iversen, B.M. 2001: Substantial loss of 125 2D3 in the urine in patients with nephrotic syndrome. Journal of the American Society of Nephrology 12(Program and Abstract Issue): 126A

Mahaffey, K.W.; Miller, J.M.; Macaulay, C.M.; Laskowitz, D.L.; Alberts, M.J.; Sloan, M.A.; Granger, C.B.; Simoons, M.L.; Topol, E.J.; Califf, R.M.; Harrington, R.A. 1999: Substantial number of patients with acute coronary syndromes at risk for stroke each year Results from the PURSUIT trial. Journal of the American College of Cardiology 33(2 Suppl A): 366A

Pappas, J.; Lin, W.L.; Helm, C.W.; Freedman, R.S.; Platsoucas, C.D. 1999: Substantial proportions of identical T cell receptor transcripts in ovarian tumor infiltrating lymphocytes. Proceedings of the American Association for Cancer Research 40: 499

Weijmer, Marcel C.; Van Den Dorpel, Marinus A.; Van Geelen, Jos A.C.A.; Groeneveld, Han O.; Van Jaarsveld, Brigit C.; Koopmans, Marion G.; Le Poole, Caatje Y.; Schrander Van Der Meer, Anita M.; Siegert, Carl E.H.; Stas, Koen J.F.; Van De Ven, Peter; Ter Wee, Pieter M. 2003: Substantial reduction of infectious complications in hemodialysis patients with trisodium citrate 30% as catheter locking solution; a prospective multicenter double-blind randomised controlled trial. Journal of the American Society of Nephrology 14(Abstracts Issue): 54A

Soubassi, L.P.; Brili, S.V.; Toutouza, M.; Vassiliadou, K.; Soubassi, S.P.; Pitsavos, C.; Stefanadis, C.; Toutouzas, P.K. 2000: Substantial risk factors for atherothrombotic vascular disease in hemodialysis patients. American Journal of Hypertension 13(4 Part 2): 285A

Buckland Wright, C.; Wolfe, F.; Ward, R.; Flowers, N.; Hayne, C. 1999: Substantial superiority of semi-flexed view in knee OA Comparative radiographic study, without fluoroscopy, of extended, MTP and schuss views. Arthritis and Rheumatism 42(9 Suppl): S293

Douek, D.C.; Vescio, R.A.; Betts, M.R.; Brenchley, J.M.; Hill, B.J.; Zhang, L.; Berenson, J.R.; Collins, R.H.; Koup, R.A. 2000: Substantial thymic output occurs in adults after hematopoietic stem cell transplant and can predict T cell reconstitution. FASEB Journal 14(6): A1074

Bevan, J.S.; Atkin, S.; Atkinson, A.B.; Bouloux, P.M.; Harris, P.; James, A.; Scanlon, M.F.; Stewart, P.M.; Wass, J.A.H.; Wardlaw, J. 2000: Substantial tumour shrinkage after primary octreotide therapy for acromegaly An open, prospective study with centralised imaging analysis. Journal of Endocrinology 164(Suppl ): P56

Klemp, J.R.; Terranova, P.; Hamidpour, S.; Kennedy, T.M.; Elia, M.; Fabian, C.J. 2002: Substantial variation of NAF estrone and estradiol levels between ducts in high-risk women. Breast Cancer Research and Treatment 76(Suppl 1): S154

Bern, C.R.; Townsend, A.R.; Farmer, G.L.; Cleveland, C.C. 2002: Substantial weathering-derived sources of strontium in a lowland tropical rainforest on 40 million-year-old soils. Ecological Society of America Annual Meeting Abstracts 87: 75-76

Saferstein, L.; Kelly, A.R. 1999: Substantially anhydrous antiseptic wipes. Official Gazette of the United States Patent and Trademark Office Patents 1224(1)

Eidenschink, T.; Lenz, J. 2003: Substantially circular catheter assembly. Official Gazette of the United States Patent and Trademark Office Patents 1273(1)

Hedstrom, L.; Lundblad, A.; Nagard, N. 2002: Substantially crystalline form of melagatran. Official Gazette of the United States Patent and Trademark Office Patents 1264(2)

Elcey, C.D.; Kunhi, A.A.M. 2010: Substantially enhanced degradation of hexachlorocyclohexane isomers by a microbial consortium on acclimation. Journal of Agricultural and Food Chemistry 58(2): 1046-1054

Halle, D.; Renbaum, P.; Orkin, B.; Farkash, A.; Segal, A.; Cherny, N.; Catane, R. 1999: Substantially improved sensitivity of urine screening for bladder cancer using genetic markers over routine cytology Preliminary data from a prospective study. Proceedings of the American Association for Cancer Research 40: 691

Stone, K.R. 1999: Substantially native meniscal cartilage heterografts. Official Gazette of the United States Patent and Trademark Office Patents 1223(4)

Staats, H.F.; Haynes, B.F.; Patel, D.D.; Sempowski, G.D. 2001: Substantially non-toxic biologically active mucosal adjuvants in vertebrate subjects. Official Gazette of the United States Patent and Trademark Office Patents 1249(1)

Wood, H.C. Swan; Suckling, C.J.; Rees, L.G. 2002: Substantially pure diastereoisomers of tetrahydrofolate derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1265(5)

Carter, G.T.; He, H. 2004: Substantially pure glycopeptide antibiotics AC-98-1; AC-98-2; AC-98-3; AC-98-4 and AC-98-5. Official Gazette of the United States Patent and Trademark Office Patents 1280(5)

Lee, S.; Mcnemar, C. 1999: Substantially pure histidine-linked protein polymer conjugates. Official Gazette of the United States Patent and Trademark Office Patents 1228(3)

Hughes, A.John Jr 2003: Substantially pure reverse transriptases and methods of production thereof. Official Gazette of the United States Patent and Trademark Office Patents 1275(1)

Fasano, A. 1999: Substantially pure zonulin, a physiological modulator of mammalian tight junctions. Official Gazette of the United States Patent and Trademark Office Patents 1225(5)

Cotter, A.; Newberg, A.B.; Hickeson, M.; Reilly, P.; Mozley, P.D.; Alavi, A. 2001: Substantially reduced partial perfusion is equal to no perfusion in predicting brain death. Journal of Nuclear Medicine 42(5 Suppl): 234P-235P

Dubnitskay, E. 2000: Substantiating the classification of personality disorders. American Journal of Medical Genetics 96(4): 509

Zaitseva, N.V.; Mai, I.V.; Shur, P.Z.; Kiryanov, D.A. 2003: Substantiation of regional criteria for the safety of chemical substances for provision of the acceptable population health hazard. Gigiena i Sanitariia 6: 31-34

Magomedova, M.A.; Morozova, L.M. 2000: Substantiation of the regional system of protected natural areas. Arctic Science Conference Abstracts 51: 80

Koshti, N.M.; Jawale, A.H.; Parab, B.B.; Naik, S.D.; Moghe, M.D.; Jadhav, T.S.; Nashte, S.S. 2003: Substantive hydrophobic cationic UV-absorbing compounds. Official Gazette of the United States Patent and Trademark Office Patents 1274(1)

Kaplan, C. 1999: Substantive topical composition. Official Gazette of the United States Patent and Trademark Office Patents 1228(4)

Koshti, N.M.; Jawale, A.H.; Parab, B.B.; Naik, S.D.; Moghe, M.D.; Jadhav, T.S.; Nashte, S.S. 2002: Substantive water-soluble bis-quaternary salts of cinnamidoalkylamines. Official Gazette of the United States Patent and Trademark Office Patents 1260(5)

Shayakhmetova, A.; Saifetdinova, G.; Kovalenko, V.; Voloshina, O. 2003: Substational of hepatoprotective action of biomelan preparation in experiment. Toxicology Letters (Shannon) 144(Suppl 1): s88

Yasuda, R.; Kinosita, K., J. 2001: Substeps in the major 120degree step of F1-ATPase. Biophysical Journal 80(1 Part 2): 503a-504a

Reynolds, H.R.; Applebaum, R.M.; Spevack, D.M.; Shah, A.; Mcaleer, E.P.; Nayar, A.C.; Tunick, P.A.; Lapietra, A.; Patel, S.; Bizekis, C.S.; Wood, M.G.; Grossi, E. 2003: Substernal epicardial echocardiography may be a critical diagnostic tool in the postoperative cardiac surgery patient. Journal of the American College of Cardiology 41(6 Suppl A): 449A

Memoli, K.A.; Strike, D.P.; Failli, A.A.; Steffan, R.J. 2001: Substitued tetrahydro-1,3,5-triazin-2 -thiones as anti-atherosclerotic agents. Official Gazette of the United States Patent and Trademark Office Patents 1248(5)

Dimagno, S.G.; Sun, H. 2002: Substituent control of metal-centered ET rates in cobalt porphyrins. Abstracts of Papers American Chemical Society 224(1-2): INOR 619

Cosimelli, B.; Spinelli, D.; Costanzo, F.; Tonelli, D.; Lamartina, L.; Sarva, M.C.; Seeber, R. 2001: Substituent effect on the redox potential of substituted thiophen-3-ylamines. Tetrahedron 57(9): 1857-1860, 25 February

Murakami, Y.; Yokoo, H.; Yokoyama, Y.; Watanabe, T. 1999: Substituent effects in the Fischer indolization of -hydrazones. Chemical and Pharmaceutical Bulletin 47(6): 791-797

Kidder, M.K.; Britt, P.F.; Buchanan, A.C.IIi 2002: Substituent effects in the pyrolysis of lignin model compounds. Abstracts of Papers American Chemical Society 223(1-2): FUEL 156

Zhang, J.; Celine, P.; Jia, S.L.; Ma, J.G.; Zhang, J.; Shelnutt, J.A.; Marchon, J.C. 1999: Substituent effects on nonplanar nickel meso-tetra porphyrins. Biophysical Journal 76(1 Part 2): A424 - A424

Cao, H.; Diaz, D.; Heagy, M. 2002: Substituent effects on saccharide selectivity in monoboronic acid sensor. Abstracts of Papers American Chemical Society 223(1-2): ORGN 251

Patoiseau, J.F.CedillaOis; Rieu, J.P.; John, G.; Legrand, B.; Verscheure, Y. 2003: Substitute 1- -3- -isothioureas, their preparation and therapeutic use. Official Gazette of the United States Patent and Trademark Office Patents 1271(4)

Brugnara, C.; Halperin, J.; Fluckiger, R.; Bellott, E.M.J.; Lombardy, R.J.; Clifford, J.J.; Gao, Y.D.; Haidar, R.M.; Kelleher, E.W.; Moussa, A.M.; Sachdeva, Y.P.; Sun, M.; Taft, H.N.; Zeldin, M.H. 2003: Substitute 11-phenyl-dibenzazepine compounds useful for the treatment or prevention of diseases characterized by abnormal cell proliferation. Official Gazette of the United States Patent and Trademark Office Patents 1268(3)

Hodge, C.N.; Fernandez, C.H.; Jadhav, P.K.; Lam, P.Y.S. 1999: Substitute caprolactams and derivatives thereof useful for treatment of HIV disease. Official Gazette of the United States Patent and Trademark Office Patents 1220(1): 535-537

Watanabe, A.; Sasaki, C.; Nonaka, M.; Matoba, H. 2002: Substitute for edible oil and fat. Official Gazette of the United States Patent and Trademark Office Patents 1262(2)

Hellendahl, B.; Lansky, A.; Munschauer, R.; Bialojan, S.; Unger, L.; Teschendorf, H.J.; Wicke, K.; Drescher, K. 2002: Substitute pyrimidine compounds and the use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1254(5)

Fadeev, V.V.; Melnichenko, G.A. 2000: Substitute therapy of primary chronic adrenal insufficiency. Problemy Endokrinologii 46(3): 31-45

Nomura, T.; Blakely, D.W.; Takatani, S.; Kawaguchi, K. 1999: Substitute-heart control apparatus. Official Gazette of the United States Patent and Trademark Office Patents 1228(2)

Daluge, S.M.; Wolberg, G.; Livingston, D.A. 2002: Substituted -1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-ylphen yl derivatives, their preparation and their use in treatment of inflammatory conditions and immune disorders. Official Gazette of the United States Patent and Trademark Office Patents 1256(2)

Daluge, S.M.; Wolberg, G.; Livingston, D.A. 2002: Substituted -1,2,3,6-tetrahydro-2,6-dioxo-9h-purin-8-yl phenyl derivatives, their preparation and their use in the treatment of inflammatory conditions and immune disorders. Official Gazette of the United States Patent and Trademark Office Patents 1261(3)

Gerlach, M.; Maul, C. 2004: Substituted 1 and 2 naphthol mannich bases. Official Gazette of the United States Patent and Trademark Office Patents 1285(2)

Grauert, M.; Carter, A.J.; Weiser, T.; Ensinger, H.A.; Gaida, W.; Mierau, J. 2002: Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and their use as pharmaceutical compositions. Official Gazette of the United States Patent and Trademark Office Patents 1258(2)

Flaugh, M.E.; Kiefer, A.D. 1999: Substituted 1,2,3,4-tetrahydro-2-dibenzofuranamines and 2-aminocyclohepta benzofurans. Official Gazette of the United States Patent and Trademark Office Patents 1225(2)

Krueger, B W.; Uhr, H.; Kanellakopulos, J.; Gesing, E R.; Wolf, H.; Turberg, A.; Mencke, N.; Erdelen, C.; Wachendorff Neumann, U.; Hartwig, J. 1999: Substituted 1,2,3,4-tetrahydro-5-nitro-pyrimidines. Official Gazette of the United States Patent and Trademark Office Patents 1219(2): 1589

Berg, S.; Florvall, L.; Ross, S.; Thorberg, S.O.ov 2000: Substituted 1,2,3,4-tetrahydronaphthalene derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1238(4)

Gerlach, M.; Przewosny, M.; Englberger, W.; Reissmueller, E.; Bloms Funke, P.; Maul, C.; Jagusch, U.P.ter 2004: Substituted 1,2,3,4-tetrahydroquinoline-2-carboxylic acid derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1280(1)

Carling, W.R.; Ladduwahetty, T.; Macleod, A.M.; Merchant, K.J.; Moore, K.W.; Sternfeld, F.; Street, L.J. 2001: Substituted 1,2,4-triazolo phthalazine derivatives as GABA alpha 5 ligands. Official Gazette of the United States Patent and Trademark Office Patents 1244(2)

Singh, C.; Puri, S.K.mar 2001: Substituted 1,2,4-trioxanes as antimalarial agents and a process of producing the substituted 1,2,4-trioxanes. Official Gazette of the United States Patent and Trademark Office Patents 1252(2)

Singh, C.; Tiwari, P.; Puri, S.K.mar 2004: Substituted 1,2,4-trioxanes useful as antimalarial agents and a process for the preparation thereof. Official Gazette of the United States Patent and Trademark Office Patents 1282(3)

Man, H.W.; Muller, G.W. 2001: Substituted 1,3,4-oxadiazoles and a method of reducing TNF-alpha level. Official Gazette of the United States Patent and Trademark Office Patents 1253(1)

Sum, F.W.; Gilbert, A.M.; Grosu, G.T.; Malamas, M.S.; Venkatesan, A.M.; Francisco, G.D. 1999: Substituted 1,3-benzodioxoles. Official Gazette of the United States Patent and Trademark Office Patents 1223(4)

Kirsch, R.; Enhsen, A.; Glombik, H.; Kramer, W.; Falk, E. 2003: Substituted 1,3-diaryl-2-pyrid-2-yl-3- propanol derivatives, process for their preparation, pharmaceuticals comprising these compounds and their use. Official Gazette of the United States Patent and Trademark Office Patents 1272(4)

Schaper, W.; Knauf, W.; Sanft, U.; Kern, M.; Ehrhardt, H.; Linkies, A.H.; Reuschling, D.B.; Bonin, W. 2001: Substituted 1,3-dioxan-5-ylamino-hererocyclic compounds, processes for their preparation and their use as pest control compositions. Official Gazette of the United States Patent and Trademark Office Patents 1249(4)

Mansour, T.S.; Jin, H. 2001: Substituted 1,3-oxathiolanes with antiviral properties. Official Gazette of the United States Patent and Trademark Office Patents 1246(2)

Desimone, R.W.; Manly, C. 2000: Substituted 1,4-dihydro-4-oxonicotinic carboxamides; GABA brain receptor ligands. Official Gazette of the United States Patent and Trademark Office Patents 1241(1)

Michne, W.F.; Pierson, M.E.ward 2000: Substituted 1,4-dihydropyrimidine-5-carboxylate compounds, their preparation and uses. Official Gazette of the United States Patent and Trademark Office Patents 1234(1)

Przewosny, M.; Stachel, H.D.; Poschen Rieder, H. 2003: Substituted 1,5-dihydropyrrol-2-one derivatives active as NMDA receptor antagonists for treatment of states of pain. Official Gazette of the United States Patent and Trademark Office Patents 1276(1)

Rieu, J.P.; Patoiseau, J.F.CedillaOis; John, G.; Legrand, B.; Verscheure, Y. 2003: Substituted 1- -3- isothioureas their preparation and their therapeutic application. Official Gazette of the United States Patent and Trademark Office Patents 1268(2)

Betageri, R. 2003: Substituted 1- imidazoles and their use as anti-inflammatory agents. Official Gazette of the United States Patent and Trademark Office Patents 1274(5)

Sharma, R. 2002: Substituted 1- indoles and their use as anti-inflammatory agents. Official Gazette of the United States Patent and Trademark Office Patents 1256(1)

Betageri, R.; Cywin, C.L.; Hargrave, K.; Hoermann, M.A.; Kirrane, T.M.; Parks, T.M.; Patel, U.R.; Proudfoot, J.R.; Sharma, R.; Sun, S.; Wang, X.J. 2003: Substituted 1- pyrazoles and their use as anti-inflammatory agents. Official Gazette of the United States Patent and Trademark Office Patents 1266(2)

Sharma, R. 2002: Substituted 1- triazoles and their use as anti-inflammatory agents. Official Gazette of the United States Patent and Trademark Office Patents 1262(3)

Steffan, R.J.; Failli, A.A. 2004: Substituted 1-aryl-3-heteroaryl-thioureas and substituted 1-aryl-3-heteroaryl-isothioureas as antiatherosclerotic agents. Official Gazette of the United States Patent and Trademark Office Patents 1279(1)

Steffan, R.J.; Failli, A.A. 2002: Substituted 1-aryl-3-heteroaryl-thioureas as antiatherosclerotic agents. Official Gazette of the United States Patent and Trademark Office Patents 1262(4)

Tomazic, A.; Huang, L.; Tucker, K.D. 2003: Substituted 1-benzazepines and derivatives thereof. Official Gazette of the United States Patent and Trademark Office Patents 1267(1)

Bourrain, S.; Macleod, A.M.; Neduvelil, J.G.; Showell, G.A. 1999: Substituted 1-indolylpropyl-4-benzyl-tetrahydropyridine derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1228(5)

Chambers, M.S.; Hobbs, S.C.; Street, L.J. 1999: Substituted 1-indolylpropyl-4-benzylpiperazine derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1224(3)

Jelley, R.A.; Macleod, A.M.; Reeve, A.J.; Sternfeld, F.; Street, L.J. 1999: Substituted 1-indolypropyl-4-phenthylpiperazadine derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1220(5): 4589

Brendel, J.; Kleeman, H.W.; Englert, H.C.; Lang, H.J.; Albus, U.; Lal, B.; Ghate, A.V. 2003: Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic , and medicament containing them. Official Gazette of the United States Patent and Trademark Office Patents 1272(5)

Muller, G.W.; Stirling, D. 2002: Substituted 1-oxo- and 1,3-dioxoisoindoline and method of reducing inflammatory cytokine levels. Official Gazette of the United States Patent and Trademark Office Patents 1257(5)

Labeeuw, B.; Gully, D.; Jeanjean, F.; Molimard, J.C.; Boigegrain, R. 2001: Substituted 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors, their preparation and pharamaceutical compositions containing them. Official Gazette of the United States Patent and Trademark Office Patents 1242(2)

Miller, C.P.; Collini, M.D.; Harris, H.A.; Keith, J.C.J. 2003: Substituted 10,11-benzo fluoren-10-ones as estrogenic agents. Official Gazette of the United States Patent and Trademark Office Patents 1272(2)

Carniato, D.; Gadek, T.R.; Knolle, J.; Gourvest, J.F.; Peyman, A.; Bodary, S.C. 2002: Substituted 11beta steroid derivatives, method for preparing same and intermediates of said method, use as medicine and compositions containing them. Official Gazette of the United States Patent and Trademark Office Patents 1265(5)

Collins, I.J.; Fletcher, S.R.; Harrison, T.; Leeson, P.D.; Moyes, C.R.; Nadin, A.J.; Rowley, M.; Sparey, T.J.; Teall, M.R. 2001: Substituted 1H-pyridinyl-2-ones as GABAA-alpha 2/3 ligands. Official Gazette of the United States Patent and Trademark Office Patents 1244(2)

Clark, R.D.; O'yang, C. 2001: Substituted 2 -4 -quinazolinones and 2- -4 -azaquinazolinones. Official Gazette of the United States Patent and Trademark Office Patents 1248(2)

Muller, G.W.; Stirling, D.I.; Chen, R.S.en Chu 2002: Substituted 2 isoindolines. Official Gazette of the United States Patent and Trademark Office Patents 1254(1)

Zimmer, O.; Boehlke, H.; Wnendt, S.; Geist, C.; Zwingenberger, K. 1999: Substituted 2, 4-imidazolidinedione compounds as pharmaceutical active ingredients. Official Gazette of the United States Patent and Trademark Office Patents 1229(3)

Tays, K.L.; Maclin, K.M.; Tiffany, C.W.; Olkowski, J.L.; Slusher, B.S.; Jackson, P.F. 1999: Substituted 2,3,4,5-tetrahydro-1H-3-benzazepines as potential cocaine antagonists. Abstracts of Papers American Chemical Society 217(1-2): MEDI 115

Cai, S.X.; Field, G.; Lan, N.C.; Wang, Y.; Xia, H. 1999: Substituted 2,3-benzodiazepin-4-ones and the use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1221(1)

Guerry, P.; Stalder, H.; Wyss, P C. 1999: Substituted 2,4-diaminopyrimidines. Official Gazette of the United States Patent and Trademark Office Patents 1219(1): 554-555

Bojarski, A.J.; Misztal, S.; Boksa, J.; Charakchieva Minol, S.; Wesolowska, A.; Tatarczynska, E.; Klodzinska, A.; Chojnacka Wojcik, E. 2001: Substituted 2- -butyl derivatives of azaspiro decane-7,9-dione and phthalimide as new 5-HT1A and 5-HT2A receptor ligands. Medicinal Chemistry Research 10(9): 634-643

Steffan, R.J.; Ashwell, M.A.; Pelletier, J.C.; Solvibile, W.R.; Matelan, E.M. 2003: Substituted 2- -hydroxy-3- -propyl ethers and substituted 2-aryl-2- -hydroxy-1- -ethylamine beta-3 adrenergic receptor agonists. Official Gazette of the United States Patent and Trademark Office Patents 1266(2)

Muller, G.W.; Stirling, D.I.; Chen, S C.; Man, H W. 1999: Substituted 2- -isoindolines and method of reducing TNFalpha levels. Official Gazette of the United States Patent and Trademark Office Patents 1219(4): 3366

Muller, G.W.; Stirling, D.I.; Chen, R.S.en Chu; Man, H.W.h 1999: Substituted 2- -isoindolines and method of reducing inflammatory cytokine levels. Official Gazette of the United States Patent and Trademark Office Patents 1226(3)

Grammenos, W.; Oberdorf, K.; Sauter, H.; Gypser, A.; Bayer, H.; Gewehr, M.; Grote, T.; Muller, B.; Ptock, A.; Rohl, F.; Hamprecht, G.; Gotz, N.; Ammermann, E.; Lorenz, G.; Strathmann, S. 2002: Substituted 2- phenylacetamides, as fungicides and pesticides. Official Gazette of the United States Patent and Trademark Office Patents 1257(3)

Guthikonda, R.; Hagmann, W.; Maccoss, M.; Shah, S.; Durette, P. 1999: Substituted 2-acylamino-pyridines as inhibitors of nitric oxide synthase. Official Gazette of the United States Patent and Trademark Office Patents 1223(1)

Riebel, H.J.; Lehr, S.; Stelzer, U.; Watanabe, Y.; Dollinger, M. 2002: Substituted 2-amino-4-alkylamino-1,3,5-triazines as herbicides. Official Gazette of the United States Patent and Trademark Office Patents 1259(2)

Lan, N.C.; Wang, Y.; Cai, S.X.ong 2002: Substituted 2-aminoacetamides and the use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1264(2)

Cai, S.X.; Wang, Y. 2003: Substituted 2-aminobenzamide caspase inhibitors and the use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1274(3)

Esser, C.; Hagmann, W.; Hoffman, W.; Shah, S.; Wong, K.; Chabin, R.; Guthikonda, R.; Maccoss, M.; Caldwell, C.; Durette, P. 1999: Substituted 2-aminopyridines as inhibitors of nitric oxide synthase. Official Gazette of the United States Patent and Trademark Office Patents 1227(4)

Hutchings, M.C.; Davis, P.D.; Moffat, D.F. Charles 2000: Substituted 2-anilinopryimidines useful as protein kinase inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1233(2)

Hutchings, M.C.; Davis, P.D.; Moffat, D.F. Charles 2002: Substituted 2-anilinopyrimidines useful as protein kinase inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1254(2)

Dodd, J.H.; Henry, J.R.; Rupert, K.C. 2003: Substituted 2-aryl-3- -imidazo pyrimidines, and related pharmaceutical compositions and methods. Official Gazette of the United States Patent and Trademark Office Patents 1273(4)

Dixon, B.R.; Bagi, C.M.; Brennan, C.R.; Brittelli, D.R.; Bullock, W.H.; Chen, J.; Collibee, W.L.; Dally, R.; Johnson, J.S.; Kluender, H.C.E.; Lathrop, W.F.; Liu, P.; Mase, C.A.; Redman, A.M.; Scott, W.J.; Urbahns, K. 2002: Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents. Official Gazette of the United States Patent and Trademark Office Patents 1256(1)

Pevarello, P.; Varasi, M.; Salvati, P.; Post, C. 2001: Substituted 2-benzylamino-2-phenyl-acetamide compounds. Official Gazette of the United States Patent and Trademark Office Patents 1251(3)

Sundermann, B.; Koegel, B.Y.; Buschmann, H. 2004: Substituted 2-dialkylaminoalkylbiphenyl derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1280(4)

Albert, R.; Meingassner, J.G.; Wattanasin, S.; Weitz Schmidt, G.; Welzenbach, K.; Hommel, U.; Ehrhardt, C.; Roche, D.; Kallen, J. 2002: Substituted 2-oxo-1,4-diazacycloalkanes. Official Gazette of the United States Patent and Trademark Office Patents 1259(1)

Himmler, T.; Pirro, F. 2001: Substituted 2-oxo-alkanoic acid- amides. Official Gazette of the United States Patent and Trademark Office Patents 1248(1)

Miller, C.P.; Collini, M.D.; Kaufman, D.H.; Morris, R.L.; Singhaus, R.R.J.; Ullrich, J.W.; Harris, H.A.; Keith, J.C.J.; Albert, L.M.; Unwalla, R.J. 2004: Substituted 2-phenyl benzofurans as estrogenic agents. Official Gazette of the United States Patent and Trademark Office Patents 1285(2)

Benes, Jan; Da Silva, Patricio Manuel Viera Araujo Soares; Learmonth, David Alexander 2003: Substituted 2-phenyl-1- -1-ethanones, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them. Official Gazette of the United States Patent and Trademark Office Patents 1266(4)

Schafer, P.; Hamprecht, G.; Menges, M.; Menke, O.; Rack, M.; Reinhard, R.; Zagar, C.; Munster, P.; Westphalen, K.O.; Otten, M.; Walter, H. 2001: Substituted 2-phenyl-3 -pyridazinones. Official Gazette of the United States Patent and Trademark Office Patents 1246(1)

Davis, P.D.; Moffat, D.F. Charles; Batchelor, M.J. 2000: Substituted 2-pyrimidineamines and processes for their preparation. Official Gazette of the United States Patent and Trademark Office Patents 1236(4)

Kozikowski, A.P.; Wang, S.; Qiao, L. 2001: Substituted 2-pyrrolidinone activators of PKC. Official Gazette of the United States Patent and Trademark Office Patents 1250(1)

Zhang, S.X.; Bastow, K.F.; Tachibana, Y.; Kuo, S.C.; Hamel, E.; Mauger, A.; Narayanan, V.L.; Lee, K.H. 1999: Substituted 2-thienyl-1,8-naphthyridin-4-ones Their synthesis, cytotoxicity, and inhibition of tubulin polymerization. Abstracts of Papers American Chemical Society 218(1-2): MEDI 171

Delucca, G.V. 2001: Substituted 2H-1,3-diazapin-2-one useful as an HIV protease inhibitor. Official Gazette of the United States Patent and Trademark Office Patents 1252(1)

Hansen, J.B.; Tagmose, T.M.; Mogensen, J.P.; Dorwald, F.Z.; Jorgensen, A.S. 2002: Substituted 3,3-diamino-2-propenenitriles, their preparation and use. Official Gazette of the United States Patent and Trademark Office Patents 1257(1)

Lee, K.H.; Xie, L.; Allaway, G.P.; Wild, C.T. 2004: Substituted 3,4-di-O-camphanoyl- -cis-khellactone analogs, compositions thereof, and methods for using thereof. Official Gazette of the United States Patent and Trademark Office Patents 1284(4)

Lattmann, R.; Acklin, P. 2002: Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators. Official Gazette of the United States Patent and Trademark Office Patents 1263(3)

O'malley, G.J.; Palermo, M.G. 1999: Substituted 3- -1, 2-benzisoxazoles and related compounds. Official Gazette of the United States Patent and Trademark Office Patents 1224(3)

O'malley, G.J.; Palermo, M.G. 2000: Substituted 3- -1,2-benzisoxazoles and related compounds. Official Gazette of the United States Patent and Trademark Office Patents 1233(1)

Desimone, R.W.; Blum, C.A. 2000: Substituted 3- -benzimidazol-2- -ones A new class of GABAA brain receptor ligands. Bioorganic and Medicinal Chemistry Letters 10(24): 2723-2726, 18 December

Semple, J.E.; Lim Wilby, M.S.; Brunck, T.K. 2000: Substituted 3-amino-2-hydroxyphenylacetamide derivatives as enzyme inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1230(1)

Wissner, A.; Hamann, P.R.; Yamashita, A. 2002: Substituted 3-cyano- , , and naphthyridine inhibitors of tyrosine kinases. Official Gazette of the United States Patent and Trademark Office Patents 1256(2)

Wissner, A.; Tsou, H.R.; Berger, D.M.; Floyd, M.B.Jr; Hamann, P.R.; Zhang, N.; Salvati, M.E.; Frost, P. 2001: Substituted 3-cyanoquinolines. Official Gazette of the United States Patent and Trademark Office Patents 1250(2)

Stransky, W.; Grauert, M.; Carter, A.; Weiser, T.; Bechtel, W.D.; Ensinger, H.; Lotz, R.R. H.; Palluk, R.; Pschorn, U. 2002: Substituted 3-phenoxy- and 3-phenylalkyloxy-2-phenyl-propylamines. Official Gazette of the United States Patent and Trademark Office Patents 1261(4)

Schoenafinger, K.; Petry, S.; Mueller, G.; Baringhaus, K.H.inz 2002: Substituted 3-phenyl-5-alkoxy-1,3,4-oxadiazol-2-ones, their preparation and their use as pharmaceuticals. Official Gazette of the United States Patent and Trademark Office Patents 1257(2)

Petry, S.; Schoenafinger, K.; Mueller, G.; Baringhaus, K.H.inz 2003: Substituted 3-phenyl-5-alkoxy-1,3,4-oxadiazol-2-ones, their preparation and their use in medicaments. Official Gazette of the United States Patent and Trademark Office Patents 1272(4)

Bullington, J.L. 2003: Substituted 3-pyridyl-4-arylpyrroles, and related therapeutic and prophylactic methods. Official Gazette of the United States Patent and Trademark Office Patents 1270(2)

Alig, B.; Marhold, A.; Stolting, J.; Gau, W.; Erdelen, C.; Turberg, A.; Mencke, N.; Hansen, O. 2003: Substituted 3-thiocarbamoylpyrazoles. Official Gazette of the United States Patent and Trademark Office Patents 1267(2)

Metzker, M.L.; Gibbs, R.A. 1999: Substituted 4,4-difluoro-4-bora-3A,4A-diaza-s-indacene compounds for homogenous amplification/detection assays. Official Gazette of the United States Patent and Trademark Office Patents 1228(5)

Li, J.H.; Zhang, J.; Kalish, V.J. 2003: Substituted 4,9-dihydrocyclopenta phenanthridine-5-ones, derivatives thereof and their uses. Official Gazette of the United States Patent and Trademark Office Patents 1269(2)

Ducharme, Y.; Blouin, M.; Brideau, C.; Chan, C.; Cote, B.; Frenette, R.; Friesen, R.W.; Girard, M.; Girard, Y.; Godbout, C.; Guay, D.; Hamel, P.; Huang, Z.; Jones, T.; Laliberte, F.; Masson, P.; Mcauliffe, M. 2001: Substituted 4- -ethylpyridine-n-oxides as potent and selective phosphodiesterase-4 inhibitors. Inflammation Research 50(Suppl 3): S187

Kane, J.M.; Maynard, G.D.; Burkholder, T.P.; Bratton, L.D.; Dalton, C.R.; Kudlacz, E.M.; Santiago, B. 2001: Substituted 4- diazepanes useful for the treatment of allergic disease. Official Gazette of the United States Patent and Trademark Office Patents 1243(4)

Maynard, G.D.; Le, T.B.nh 2002: Substituted 4- diazepanes useful for the treatment of allergic diseases. Official Gazette of the United States Patent and Trademark Office Patents 1260(4)

Frenette, R.; Blouin, M.; Brideau, C.; Chan, C.; Chauret, N.; Ducharme, Y.; Friesen, R.W.; Girard, Y.; Hamel, P.; Huang, Z.; Jones, T.; Laliberte, F.; Li, C.; Masson, P.; Mcauliffe, M. 2001: Substituted 4- pyridine-n-oxides as phosphodiesterase-4 inhibitors SAR study directed toward the improvement of pharmacokinetic parameters. Abstracts of Papers American Chemical Society 221(1-2): MEDI 247

Preuss, R.; Salbeck, G.; Salbeck, G.; Schaper, W.; Braun, P.; Knauf, W.; Sachse, B.; Waltersdorfer, A.; Kern, M.; Luemmen, P. 1999: Substituted 4-alkoxypyrimidines, process for their preparation, agents containing them, and their use as pesticides. Official Gazette of the United States Patent and Trademark Office Patents 1218(2): 1352-1353

Schindler, U.; Schoenafinger, K.; Strobel, H. 2003: Substituted 4-amino-2-aryl-cyclopenta pyrimidines, their production and use and pharmaceutical preparations containing same. Official Gazette of the United States Patent and Trademark Office Patents 1274(5)

Schindler, U.; Schonafinger, K.; Strobel, H. 2003: Substituted 4-amino-2-aryl-tetrahydoquinazolines, their preparation, their use and pharmaceutical preparations comprising them. Official Gazette of the United States Patent and Trademark Office Patents 1277(2)

Calderwood, D.J.; Johnston, D.N.; Rafferty, P.; Twigger, H.L.; Munschauer, R.; Arnold, L. 1999: Substituted 4-amino-7H-pyrrolo -pyrimidines as PTK inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1229(2)

Chong, W.K.M.; Chu, S.S.; Li, L.; Duvadie, R.K.; Yang, Y.; Xiao, W. 2003: Substituted 4-amino-thiazol-2-yl compounds as cyclin-dependent kinase inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1270(4)

Kluender, H.C.E.; Dixon, B.R.; Brittelli, D.R. 1999: Substituted 4-arylbutyric acid derivatives as matrix metalloprotease. Official Gazette of the United States Patent and Trademark Office Patents 1218(4): 3129

Cheetham, S.C.; Kerrigan, F.; Jones, C.G. Pryce 2001: Substituted 4-arylmethylene-2-imino-2,3-dihydrothiazoles and derivatives and their pharmaceutical use. Official Gazette of the United States Patent and Trademark Office Patents 1243(2)

Engel, S.; Baumann, E.; Von Deyn, W.; Hill, R.L.; Kardorff, U.; Mayer, G.; Otten, M.; Rheinheimer, J.; Wagner, O.; Witschel, M.; Misslitz, U.; Walter, H. 2002: Substituted 4-benzoylpyrazoles. Official Gazette of the United States Patent and Trademark Office Patents 1259(3)

Hofmeister, A.; Falk, E.; Kleemann, H.W.; Jansen, H.W.; Bickel, M. 2002: Substituted 4-benzylaminoquinolines and their hetero analogs, process for their preparation, pharmaceuticals containing these compounds and use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1254(3)

Kluender, H.C.E.; Dixon, B.R.; Vanzandt, M.C.; Wilhelm, S.M.; Wolanin, D.J.; Wood, J.E. 1999: Substituted 4-biarylbutyric acid derivatives as matrix metalloprotease inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1218(3): 2234-2235

Kluender, H.C. Eugene; Brittelli, D.R.; Schoen, W.R.; Ha, S.N. 2001: Substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1250(2)

Kluender, H.C.; Bjorge, S.M.; Zadjura, L.M.; Brubaker, W.F. 1999: Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as matrix metalloprotease inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1225(3)

Willson, T.M.; Mook, R.A.; Kaldor, I.; Henke, B.R.; Deaton, D.N.; Collins, J.L.; Cobb, J.E.; Brackeen, M.; Sharp, M.J.; O'callaghan, J.M.; Erickson, G.A.; Boswell, G.E. 2001: Substituted 4-hydroxy-phenylalcanoic acid derivatives with agonist activity to PPAR-gamma. Official Gazette of the United States Patent and Trademark Office Patents 1250(4)

Albaugh, P.A.; Desimone, R.W.; Liu, G. 2000: Substituted 4-oxo-napthyridine-3-carboxamides GABA brain receptor ligands. Official Gazette of the United States Patent and Trademark Office Patents 1240(1)

Albaugh, P.A.; Currie, K.S.; Rosewater, D.; Cai, G. 2002: Substituted 4-oxo-quinoline-3-carboxamides. Official Gazette of the United States Patent and Trademark Office Patents 1260(1)

Godel, T.; Hoffmann, T.; Schnider, P.; Stadler, H. 2004: Substituted 4-phenyl-pyridine compounds with activity as antagonists of neurokinin 1 receptors. Official Gazette of the United States Patent and Trademark Office Patents 1285(1)

Gully, D.; Roger, P.; Wermuth, C.G. 1999: Substituted 4-phenylaminothiazoles, their process of preparation and the pharmaceutical compositions containing them. Official Gazette of the United States Patent and Trademark Office Patents 1220(2): 1564

Hofmeister, A.; Lang, H.J.; Heinelt, U.; Bleich, M.; Wirth, K. 2004: Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as a medicament, and medicament containing them. Official Gazette of the United States Patent and Trademark Office Patents 1280(2)

Aronov, A.M.; Munagala, N.R.; Ortiz, D.M.ntellano, P.R.; Kuntz, I.D.; Wang, C.C. 2001: Substituted 4-phthalimidocarboxanilides as inhibitors of purine salvage phosphoribosyltransferases. Official Gazette of the United States Patent and Trademark Office Patents 1245(4)

Cai, G.; Liu, G.; Albaugh, P.A. 2002: Substituted 4H-1,4-benzothiazine-2-carboxamide GABA brain receptor ligands. Official Gazette of the United States Patent and Trademark Office Patents 1262(2)

Hayama, T.; Otake, N.; Nishikibe, M. 2002: Substituted 5- cyclopentenopyridine derivative. Official Gazette of the United States Patent and Trademark Office Patents 1260(1)

Lee, L.F.; Banerjee, S.C.; Huang, H.C.; Li, J.J.; Miller, R.E.; Reitz, D.B.; Tremont, S.J. 2000: Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake. Official Gazette of the United States Patent and Trademark Office Patents 1237(4)

Kluender, H.C. Eugene; Benz, G.H. Heinz, H. Brittelli, D.R.; Bullock, W.H.; Combs, K.J.; Dixon, B.R.; Schneider, S.; Wood, J.E.; Vanzandt, M.C.; Wolanin, D.J.; Wilhelm, S.M. 2000: Substituted 5-biarylpentanoic acids and derivatives as matrix metalloprotease inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1241(4)

Appere, G.; Erdelmeier, I.; Banissi, C.; Moutet, M.; Hopper, A. 2001: Substituted 5-biphenyl-3,4-dihydroxy-2 -furanones and method of use therefor. Official Gazette of the United States Patent and Trademark Office Patents 1248(4)

Zoller, G.; Klingler, O.; Jablonka, B.; Just, M.; Breipohl, G.; Knolle, J.; Konig, W.; Stilz, H.U.rich 1999: Substituted 5-membered ring heterocycles, their preparation and their use. Official Gazette of the United States Patent and Trademark Office Patents 1228(2)

Konkoy, C.S.; Fick, D.B.; Cai, S.X.; Lan, N.C.; Keana, J.F.W. 2004: Substituted 5-oxo-5, 6, 7, 8-tetrahydro-4H-1-benzopyrans. Official Gazette of the United States Patent and Trademark Office Patents 1287(1)

Konkoy, C.S.; Fick, D.B.; Cai, S.X.; Lan, N.C.; Keana, J.F.W. 2004: Substituted 5-oxo-5,6,7,8-tetrahydro-4H-1-benzopyrans and benzothiopyrans and the use thereof as potentiators of AMPA. Official Gazette of the United States Patent and Trademark Office Patents 1278(3)

Chupakhin, O.N.; Sidorova, L.P.; Tarakhty, E.A.; Novikova, A.P.; Perova, N.M.; Vinogradov, V.A.; Van Ginkel, M.F. 2000: Substituted 6-R-1,3,4-thiadiazine-2-amines, the use thereof as anaesthetizing, cardiovascular and hypometabolic agents, and a pharmaceutical composition containing them. Official Gazette of the United States Patent and Trademark Office Patents 1238(2)

Gutterer, B. 2001: Substituted 6-alkylphenanthridines. Official Gazette of the United States Patent and Trademark Office Patents 1245(2)

Artico, Marino; La Colla, Paolo 2003: Substituted 6-benzyl-4-oxopyrimidines, process for their preparation and pharmaceutical compositions containing them. Official Gazette of the United States Patent and Trademark Office Patents 1275(3)

Gutterer, B. 2000: Substituted 6-phenylphenanthridines. Official Gazette of the United States Patent and Trademark Office Patents 1238(3)

Chupakhin, O.N.; Sidorova, L.P.; Tarakhty, E.A.; Novikova, A.P.; Perova, N.M.; Vinogradov, V.A. 2000: Substituted 6H-1,3,4-thiadiazine-2-amines, the use thereof as anaesthetising, cardiovascular and hypometabolic agents, and a pharmaceutical composition containing them. Official Gazette of the United States Patent and Trademark Office Patents 1231(4)

Chupakhin, O.N.; Sidorova, L.P.; Tarakhty, E.A.; Novikova, A.P.; Perova, N.M.; Vinogradov, V.A.; Van Ginkel, M.F. 2001: Substituted 6H-1,3,4-thiadiazine-2-amines, the use thereof as anaesthetising, cardiovascular and hypometabolic agents, and pharmaceutical composition containing them. Official Gazette of the United States Patent and Trademark Office Patents 1252(1)

Litvinov, V.P.; Roman, S.V.; Dyachenko, V.D. 2000: Substituted 7-alkylseleno-1,4-dihydro-1,6-naphthyridines A new perspective substrates in synthesis of heterocycles with potential biological activity. Doklady Akademii Nauk 374(6): 780-785

Jaehne, G.; Lang, H.J.; Gossel, M.; Bickel, M. 2002: Substituted 8,8a-dihydro-3ah-indeno thiazoles, processes for their preparation and their use as medicaments. Official Gazette of the United States Patent and Trademark Office Patents 1259(4)

Deschenes, D.; Dube, D.; Gallant, M.; Girard, Y.; Lacombe, P.; Macdonald, D.; Mastracchio, A.; Perrier, H. 2002: Substituted 8-arylquinoline phosphodiesterase-4 inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1259(4)

Linden, J.M.; Jacobson, K.A.; Kim, Y.C.ul 2003: Substituted 8-phenylxanthines useful as antagonists of A2B adenosine receptors. Official Gazette of the United States Patent and Trademark Office Patents 1269(2)

Peck, J.V.; Wysocki, R.J.; Uwaydah, I.M.; Cusack, N.J. 1999: Substituted 9-alkyladenines. Official Gazette of the United States Patent and Trademark Office Patents 1228(2)

Darrow, James W.; Maynard, George D.; Horvath, Raymond F.; Tran, Jennifer; De Lombaert, Stephane 2001: Substituted 9H-pyridino indole and 9H-pyrimidino indole derivatives selective neuropeptide Y receptor ligands. Official Gazette of the United States Patent and Trademark Office Patents 1245(4)

Treiber, H.J.; Blank, S.; Starck, D.; Unger, L.; Teschendorf, H.J.; Wicke, K. 2002: Substituted AZA- and diazacycloheptane and -cyclooctane. Official Gazette of the United States Patent and Trademark Office Patents 1256(1)

Sikorski, J.A.; Durley, R.C.; Mischke, D.A.; Reinhard, E.J.; Fobian, Y.M.; Tollefson, M.B.; Wang, L.; Grapperhaus, M.L.; Hickory, B.S.; Massa, M.A.; Norton, M.B.; Vernier, W.F.; Parnas, B.L.; Promo, M.A.; Hamme, A.T.; Spangler, D 2004: Substituted N, N-disubstituted mercapto amino compounds useful for inhibiting cholesteryl ester transfer protein activity. Official Gazette of the United States Patent and Trademark Office Patents 1278(2)

Sikorski, J.A.; Durley, R.C.; Mischke, D.A.; Reinhard, E.J.; Fobian, Y.M.; Tollefson, M.B.; Wang, L.; Grapperhaus, M.L.; Hickory, B.S.; Massa, M.A.; Norton, M.B.; Vernier, W.F.; Parnas, B.L.; Promo, M.A.; Hamme, A.T.; Spangler, D 2004: Substituted N,N-bis-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity. Official Gazette of the United States Patent and Trademark Office Patents 1278(2)

Sikorski, J.A.; Durley, R.C.; Mischke, D.A.; Reinhard, E.J.; Fobian, Y.M.; Tollefson, M.B.; Wang, L.; Grapperhaus, M.L.; Hickory, B.S.; Massa, M.A.; Norton, M.B.; Vernier, W.F.; Parnas, B.L.; Promo, M.A.; Hamme, A.T.; Spangler, D 2004: Substituted N,N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity. Official Gazette of the United States Patent and Trademark Office Patents 1278(4)

Sikorski, J.A.; Durley, R.C.; Mischke, D.A.; Reinhard, E.J.; Fobian, Y.M.; Tollefson, M.B.; Wang, L.; Grapperhaus, M.L.; Hickory, B.S.; Massa, M.A.; Norton, M.B.; Vernier, W.F.; Parnas, B.L.; Promo, M.A.; Hamme, A.T.; Spangler, D 2004: Substituted N,N-disubstituted diamino compounds useful for inhibiting cholesteryl ester transfer protein activity. Official Gazette of the United States Patent and Trademark Office Patents 1278(2)

Sikorski, J.A.; Durley, R.C.; Mischke, D.A.; Reinhard, E.J.; Fobian, Y.M.; Tollefson, M.B.; Wang, L.; Grapperhaus, M.L.; Hickory, B.S.; Massa, M.A.; Norton, M.B.; Vernier, W.F.; Parnas, B.L.; Promo, M.A.; Hamme, A.T.; Spangler, D 2004: Substituted N,N-disubstituted fused-heterocyclo amino compounds useful for inhibiting cholesteryl ester transfer protein activity. Official Gazette of the United States Patent and Trademark Office Patents 1279(4)

Sikorski, J.A.; Durley, R.C.; Mischke, D.A.; Reinhard, E.J.; Fobian, Y.M.; Tollefson, M.B.; Wang, L.; Grapperhaus, M.L.; Hickory, B.S.; Massa, M.A.; Norton, M.B.; Vernier, W.F.; Parnas, B.L.; Promo, M.A.; Hamme, A.T.; Spangler, D 2004: Substituted N,N-disubstituted non-fused heterocyclo amino compounds useful for inhibiting cholesteryl ester transfer protein activity. Official Gazette of the United States Patent and Trademark Office Patents 1280(1)

John, C.S.; Lim, B.B.; Vilner, B.J.; Bowen, W.D. 1999: Substituted N- -N-methyl-2- ethylamine and its analogs as new sigma receptor markers Synthesis, characterization, and in-vivo evaluation. Journal of Labelled Compounds and Radiopharmaceuticals 42(Suppl 1): S411-S413

Ewing, W.R.; Becker, M.R.; Pauls, H.W.; Cheney, D.L.; Mason, J.S.; Spada, A.P.; Choi Sledeski, Y.M. 1999: Substituted N- -azaheterocyclylamide compounds. Official Gazette of the United States Patent and Trademark Office Patents 1226(4)

Cai, S.X.; Drewe, J.; Zhang, H.Z. 2004: Substituted N- -benzhydrazides, N -benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1281(1)

Kruger, M.; Prien, O.; Steinmeyer, A.; Kroll, J.; Ernst, A.; Siemeister, G.; Haberey, M.; Hoffmann, J. 2004: Substituted N- derivatives, their production and use as pharmaceutical agents. Official Gazette of the United States Patent and Trademark Office Patents 1283(2)

Kumar, V.; Dority, J.A.an 1999: Substituted N-arylmethyl and heterocylylmethyl-1H-pyrazolo quinolin-4-amines and compositions and methods of use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1229(4)

Gunther, Eckhard; Emig, Peter; Reichert, Dietmar; Le Baut, Guillaume; Nickel, Bernd; Bacher, Gerald 2002: Substituted N-benzylindol-3-ylglyoxylic acid derivatives having antitumor action. Official Gazette of the United States Patent and Trademark Office Patents 1261(2)

Caldwell, C.G.; Chapman, K.T.; Esser, C.K.; Hagmann, W.K.; Kopka, I.E.; Polo, S.A.; Sahoo, S.P.; Durette, P.L. 1999: Substituted N-carboxyalkylpeptidyl derivatives as antidegenerative active agents. Official Gazette of the United States Patent and Trademark Office Patents 1225(1)

Durette, P.L.; Esser, C.K.; Hagmann, W.K.; Kopka, I.E. 2000: Substituted N-carboxyalkylpeptidyl derivatives as antidegenerative agents. Official Gazette of the United States Patent and Trademark Office Patents 1236(3)

Breipohl, G.; Uhlmann, E.; Knolle, J. 2000: Substituted N-ethylglycine derivatives for preparing PNA and PNA/DNA hybrids. Official Gazette of the United States Patent and Trademark Office Patents 1235(2)

Sikorski, J.A.; Durley, R.C.; Mischke, D.A.; Reinhard, E.J.; Fobian, Y.M.; Tollefson, M.B.; Wang, L.; Grapperhaus, M.L.; Hickory, B.S.; Massa, M.A.; Norton, M.B.; Vernier, W.F.; Parnas, B.L.; Promo, M.A.; Hamme, A.T.; Spangler, D 2004: Substituted N-fused-phenyl-N-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity. Official Gazette of the United States Patent and Trademark Office Patents 1280(4)

Puerstinger, G.; Knapp, A.; Pruenster, M.; Witvrouw, M.; Pannecouque, C.; Balzarini, J.; De Clercq, E. 2001: Substituted N-heteroaryl-N- thiourea derivatives as human immunodeficiency virus reverse transcriptase inhibitors Synthesis and structure-activity relationship. Antiviral Research 50(1): A47

Sikorski, J.A.; Durley, R.C.; Mischke, D.A.; Reinhard, E.J.; Fobian, Y.M.; Tollefson, M.B.; Wang, L.; Grapperhaus, M.L.; Hickory, B.S.; Massa, M.A.; Norton, M.B.; Vernier, W.F.; Parnas, B.L.; Promo, M.A.; Hamme, A.T.; Spangler, D 2003: Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity. Official Gazette of the United States Patent and Trademark Office Patents 1272(1)

Maynard, G.P.; Kane, J.M.; Bratton, L.D.; Kudlacz, E.M. 1999: Substituted N-methyl-N- -2- butylbenzamides useful for the treatment of allergic diseases. Official Gazette of the United States Patent and Trademark Office Patents 1229(1)

Maynard, G.D.; Kane, J.M.; Dalton, C.R.; Santiago, B.; Kudlacz, E.M.; Bratton, L.D. 1999: Substituted N-methyl-N- diazepan-1-yl-2-. Official Gazette of the United States Patent and Trademark Office Patents 1225(1)

Bratton, L.D.; Dalton, C.R.; Kudlacz, E.M.; Maynard, G.D.; Kane, J.M.; Santiago, B. 1999: Substituted N-methyl-N- piperidin-1-YL-2-. Official Gazette of the United States Patent and Trademark Office Patents 1224(2)

Kanellakopulos, J.; Findeisen, K.; Linker, K.H.; Erdelen, C.; Turberg, A.; Mencke, N. 2000: Substituted N-methylenethioureas as pesticides. Official Gazette of the United States Patent and Trademark Office Patents 1234(3)

Sikorski, J.A.; Durley, R.C.; Mischke, D.A.; Reinhard, E.J.; Fobian, Y.M.; Tollefson, M.B.; Wang, L.; Grapperhaus, M.L.; Hickory, B.S.; Massa, M.A.; Norton, M.B.; Vernier, W.F.; Parnas, B.L.; Promo, M.A.; Hamme, A.T.; Spangler, D 2004: Substituted N-phenoxy-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity. Official Gazette of the United States Patent and Trademark Office Patents 1279(4)

Butlin, R.J.; Pease, J.E.; Block, M.H.; Nowak, T.; Burrows, J.N. 2004: Substituted N-phenyl 2-hydroxy-2-methyl-3,3,3-trifluoropropanamide derivatives which elevate pyruvate dehydrogenase activity. Official Gazette of the United States Patent and Trademark Office Patents 1279(2)

Sikorski, J.A.; Durley, R.C.; Mischke, D.A.; Reinhard, E.J.; Fobian, Y.M.; Tollefson, M.B.; Wang, L.; Grapperhaus, M.L.; Hickory, B.S.; Massa, M.A.; Norton, M.B.; Vernier, W.F.; Parnas, B.L.; Promo, M.A.; Hamme, A.T.; Spangler, D.P. 2002: Substituted N-phenyl-N-heteroaralkyl aminoalcohol compounds for inhibiting cholesteryl ester transfer protein activity. Official Gazette of the United States Patent and Trademark Office Patents 1263(1)

Sikorski, J.A.; Durley, R.C.; Mischke, D.A.; Reinhard, E.J.; Fobian, Y.M.; Tollefson, M.B.; Wang, L.; Grapperhaus, M.L.; Hickory, B.S.; Massa, M.A.; Norton, M.B.; Vernier, W.F.; Parnas, B.L.; Promo, M.A.; Hamme, A.T.; Spangler, D 2004: Substituted N-phenyl-N-heteroaralkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity. Official Gazette of the United States Patent and Trademark Office Patents 1278(2)

Moschel, R.C.; Pegg, A.E.; Dolan, M.E.; Chae, M.Y. 2002: Substituted O6-benzyl-8-aza-guanines. Official Gazette of the United States Patent and Trademark Office Patents 1261(3)

Moschel, R.C.; Pegg, A.E.; Dolan, M.E.; Chae, M.Y. 2001: Substituted O6-benzyl-8-aza-guanines and 6 -benzyloxypyrimidines. Official Gazette of the United States Patent and Trademark Office Patents 1242(2)

Moschel, R.C.; Pegg, A.E.; Dolan, M.E.; Chae, M.Y. 2001: Substituted O6-benzylguanines. Official Gazette of the United States Patent and Trademark Office Patents 1253(4)

Amano, S.; Taoka, N.; Mitsuda, M.; Inoue, K. 2003: Substituted acetylpridine derivatives and process for the preparation of intermediates for optically active beta-3 agonist by the use of the same. Official Gazette of the United States Patent and Trademark Office Patents 1267(1)

Amano, S.; Taoka, N.; Mitsuda, M.; Inoue, K. 2003: Substituted acetylpyridine derivatives and process for the preparation of intermediates for optically active beta3 agonist by the use of the same. Official Gazette of the United States Patent and Trademark Office Patents 1276(1)

Cheng, P.T.; Devasthale, P.; Jeon, Y.; Chen, S.; Zhang, H. 2002: Substituted acid derivatives useful as antidiabetic and antiobesity agents and method. Official Gazette of the United States Patent and Trademark Office Patents 1260(1)

Kleemann, H.W.; Hofmeister, A.; Falk, E.; Jansen, H.W.; Schafer, H.L. 2002: Substituted acylguanidines, process for their preparation, their use as medicaments or diagnostics, and medicaments comprising them. Official Gazette of the United States Patent and Trademark Office Patents 1262(3)

Man, H.W.; Muller, G.W.; Huang, S.Y. 2004: Substituted acylhydroxamic acids and method of reducing TNFalpha levels. Official Gazette of the United States Patent and Trademark Office Patents 1280(1)

Muller, G.W.; Man, H.W.h 2001: Substituted alkanohydroxamic acids and method of reducing TNFalpha levels. Official Gazette of the United States Patent and Trademark Office Patents 1245(2)

Varkhedkar, V.; Palle, V.P.; Zablocki, J.; Elzein, E.; Blackburn, B.K. 2002: Substituted alkyl piperazine derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1262(3)

Elzein, E.; Zablocki, J.; Marquart, T. 2003: Substituted alkylene diamine compounds. Official Gazette of the United States Patent and Trademark Office Patents 1275(4)

Yamamoto, A.; Nakamura, K.; Otsuka, M. 2000: Substituted alkyltetraamine derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1238(3)

Stolle, Andreas; Antonicek, Horst Peter; Lensky, Stephen; Voerste, Arnd; Muller, Thomas; Baumgarten, Jorg; Von Dem Bruch, Karsten; Muller, Gerhard; Stropp, Udo; Horvath, Ervin; De Vry, Jean Marie Viktor; Schreiber, Rudy 2002: Substituted alpha, beta-anellated butyrolactones. Official Gazette of the United States Patent and Trademark Office Patents 1263(2)

Dack, K.N.; Whitlock, G.A. 2000: Substituted alpha-aminosulphonyl-acetohydroxamic acids as therapeutic agents. Official Gazette of the United States Patent and Trademark Office Patents 1236(3)

Wang, Y.; Cai, S.X.; Weber, E.; Mills, G.B.; Green, D.R.; Guan, L. 2002: Substituted alpha-hydroxy acid caspase inhibitors and the use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1265(3)

Iwasawa, Y.; Aoyama, T.; Kawakami, K.; Arai, S.; Satoh, T.; Monden, Y. 2000: Substituted amide derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1233(2)

Kolotova, N.V.; Dolzhenko, A.V.; Koz'minykh, V.O.; Godina, A.T.; Kotegov, V.P. 1999: Substituted amides and hydrazides of 1,4-carboxylic acids Communication 8 Synthesis and hypoglycemic activity of succinic acid substituted amides and hydrazides. Khimiko-Farmatsevticheskii Zhurnal 33(12): 9-11

Kolotova, N.V.; Koz'minykh, E.N.; KollaV.E.; Sytopyatov, B.Y.; Voronina, E.V.; Kos'minykh, V.O. 1999: Substituted amides and hydrazides of 1,4-dicarboxylic acid 7 Synthesis and pharmacological activity of some maleic, succinic and phthalic acid acylhydrazides. Khimiko-Farmatsevticheskii Zhurnal 33(5): 22-28

Dolzhenko, A.V.; Kolotova, N.V.; Koz'minykh, V.O.; Syropyatov, B.Y.; Kotegov, V.P.; Godina, A.T.; Rudakova, G.V. 2003: Substituted amides and hydrazides of dicarboxylic acids Communication 13 Synthesis and hypoglycemic activity of certain substituted amides and acylhydrazides of phthalic acid. Khimiko-Farmatsevticheskii Zhurnal. 37(1): 21-23

Anonymous 2002: Substituted amides and hydrazides of dicarboxylic acids Part 11 Synthesis and hypertensive activity of some pyridylamides of certain dicarboxylic acids. Khimiko-Farmatsevticheskii Zhurnal. 36(3): 17-19

Dolzhenko, A.V.; Kologlova, N.V.; Koz'minyx, V.O.; Syrolyatov, B.Y.; Kotegov, V.P.; Godina, A.T. 2002: Substituted amides and hydrazides of dicarboxylic acids Part 12 Synthesis and hyperglycemic and hypertensive activity of pyridylamides and certain acylhydrazides of maleic and citraconic acids. Khimiko-Farmatsevticheskii Zhurnal 36(4): 11-12

Dolzhenko, A.V.; Kolotova, N.V.; Koz'minykh, V.O.; Vasilyuk, M.V.; Kotegov, V.P.; Novoselova, G.N.; Syropratov, B.Y.; Vakhrin, M.I. 2003: Substituted amides and hydrazides of dicarboxylic acids Part 14 Synthesis and antimicrobial and anti-inflammatory activity of 4-antipyrylamides, 2-thiazolylamides, and 1-triazolylamides of certain dicarboxylic acids. Khimiko-Farmatsevticheskii Zhurnal 37(3): 42-44

Dolzhenko, A.V.; Koz'minykh, V.O.; Kolotova, N.V.; Syropyatov, B.Y.; Novoselova, G.N. 2003: Substituted amides and hydrazides of dicarboxylic acids Part 16 Synthesis and antibacterial activity of certain amides and acylhydrazides of succinic acid. Khimiko-Farmatsevticheskii Zhurnal 37(5): 10-12

Dolzhenko, A.V.; Koz'minykh, V.O.; Kolotova, N.V.; Burdu, N.Z.; Kotegov, V.P.; Novoselova, G.N.; Syropyatov, B.Y. 2003: Substituted amides and hydrazides of dicarboxylic acids Part 17 Synthesis and study of the antibacterial and anticonvulsant activity of certain substituted phthalic acid amides and acylhydrazides. Khimiko-Farmatsevticheskii Zhurnal 37(7): 7-9

Dolzhenko, A.V.; Syropyatov, B.Y.; Koz'minykh, V.O.; Kolotova, N.V.; Zakhmatov, A.V.; Borodin, A.Y. 2003: Substituted amides and hydrazides of dicarboxylic acids Part 18 Hypertensive activity of 3 -methyl-2-pyridylamides of some dicarboxylic acids. Khimiko-Farmatsevticheskii Zhurnal 37(8): 12-13

Dolzhenko, A.V.; Kolotova, N.V.; Koz'minykh, V.O.; Syropyatov, B.Y.; Kotegov, V.P.; Godina, A.T. 2002: Substituted amides and hydrazides of dicarboxylic acids Report 10 Synthesis and pharmacological activity of substituted amides and hydrazides of succinic acid. Khimiko-Farmatsevticheskii Zhurnal 36(2): 6-8

Safar, P.; Walser, A.; Shimshock, S.J.mes 2004: Substituted amides, sulfonamides and ureas useful for inhibiting kinase activity. Official Gazette of the United States Patent and Trademark Office Patents 1285(3)

Lubisch, W.; Moller, A.; Treiber, H.J.; Knopp, M. 2004: Substituted amides, their preparation and use. Official Gazette of the United States Patent and Trademark Office Patents 1283(4)

Lubisch, W.; Moller, A.; Treiber, H.J.; Knopp, M. 2002: Substituted amides, their production and their use. Official Gazette of the United States Patent and Trademark Office Patents 1262(2)

Hagmann, W.K.; Delaszlo, S.E.; Kamenecka, T.; Maccoss, M. 2004: Substituted amidine derivatives as inhibitors of cell adhesion. Official Gazette of the United States Patent and Trademark Office Patents 1282(2)

Matsumoto, Y.zo; Akamatsu, Seijiro; Ichihara, Masato; Kawasaki, Tomihisa; Kaku, Seiji; Yanagisawa, Isao 2000: Substituted amidinobenzene derivatives and medicinal compositions thereof. Official Gazette of the United States Patent and Trademark Office Patents 1234(1)

Nakayama, T.; Kawamura, H.; Uchiyama, H. 1999: Substituted amidinonaphthyl ester derivative. Official Gazette of the United States Patent and Trademark Office Patents 1220(4): 3561

Harter, M.; Albrecht, B.; Gerisch, M.; Handke, G.; Hutter, J.; Jensen, A.; Krahn, T.; Mittendorf, J.; Oehme, F.; Schlemmer, K.H.; Steinhagen, H. 2003: Substituted amidoalkyl-uracils and their use. Official Gazette of the United States Patent and Trademark Office Patents 1276(3)

Connolly, P.J.; Bandurco, V.T.; Wetter, S.K.; Johnson, S.; Bussolari, J.; Murray, W.V. 2001: Substituted amino acids as erythropoietin mimetics. Official Gazette of the United States Patent and Trademark Office Patents 1251(5)

Wachter, M.P.; Lalan, P. 2001: Substituted amino acids as neutral sphingomyelinase inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1251(4)

Singh, R.; Zhou, N.; Guo, D.; Micetich, R.G. 2001: Substituted amino bicyclic-beta-lactam penam and cepham derivatives as cysteine protease inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1246(3)

Zimmer, O.; Strassburger, W.W. Alfred; Buschmann, H.H.; Englberger, W.; Friderichs, E.J. 2000: Substituted amino compounds and their use as substances having an analgesic effect. Official Gazette of the United States Patent and Trademark Office Patents 1231(2)

Coats, S.J.; Fitzpatrick, L.J.; Hlasta, D.J.; Lanter, C.L.; Macielag, M.J.; Pan, K.; Rivero, R.A.; Palmer, S.S. 2003: Substituted aminoalkylamide derivatives as antagonists of follicle stimulating hormone. Official Gazette of the United States Patent and Trademark Office Patents 1271(4)

Takemura, M.; Kimura, Y.; Takahashi, H.; Kimura, K.; Miyauchi, S.; Ohki, H.; Sugita, K.; Miyauchi, R. 2000: Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1238(3)

Goldin, S.M.; Katragadda, S.; Hu, L.Y.; Reddy, N.L.; Fischer, J.B.; Knapp, A.G.; Margolin, L.D. 2000: Substituted aminoguanidines and methods of use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1235(1)

Barbachyn, M.R.; Morris, J.; Wishka, D.G.; Cleek, G.J.; Thomas, R.C. 2000: Substituted aminophenyl isoxazoline derivatives useful as antimicrobials. Official Gazette of the United States Patent and Trademark Office Patents 1234(5)

Uehara, M.; Watanabe, M.; Kimura, M.; Morimoto, M.; Yoshida, M. 2002: Substituted aminoquinazolinone derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same. Official Gazette of the United States Patent and Trademark Office Patents 1262(4)

Hagmann, W.K.; Springer, M.S. 1999: Substituted aminoquinolines as modulators of chemokine receptor activity. Official Gazette of the United States Patent and Trademark Office Patents 1224(1)

Seitz, T.; Stelzer, U.; Wolfrum, P.; Stenzel, K. 2001: Substituted aminosalicyclic acid amides with fungicidal effect and intermediate products for production thereof. Official Gazette of the United States Patent and Trademark Office Patents 1243(4)

Seitz, T.; Stelzer, U.; Wolfrum, P.; Stenzel, K. 2002: Substituted aminosalicylic acid amides with fungicidal effect and intermediate products for production thereof. Official Gazette of the United States Patent and Trademark Office Patents 1257(5)

Chebli, C.; Moussa, I.; Buczkowski, S.; Cartilier, L. 1999: Substituted amylose as a matrix for sustained drug release. Pharmaceutical Research 16(9): 1436-1440

Yoshikawa, Y.kihiro; Tomiya, Kanji; Tomura, Naofumi; Katsuta, Hiroyuki; Takahashi, Osamu; Inami, Shunichi; Yanase, Y.ji; Kishi, Junro; Kawashima, Hideo 1999: Substituted anilide derivative. Official Gazette of the United States Patent and Trademark Office Patents 1227(2)

Diehl, R.E.; Luo, T.; Treacy, M.F.; Barnes, K.D.; Kameswaran, V. 2002: Substituted anilide insecticidal agents. Official Gazette of the United States Patent and Trademark Office Patents 1256(3)

Astles, P.C.; Clark, D.E.; Collis, A.J.; Cox, P.J.; Eastwood, P.R.; Harris, N.V.; Quai Lai, J.Y.; Morley, A.D.; Porter, B. 2002: Substituted anilides. Official Gazette of the United States Patent and Trademark Office Patents 1264(2)

Hamprecht, G.; Menke, O.; Puhl, M.; Reinhard, R.; Sagasser, I.; Zagar, C. 2004: Substituted aniline compounds. Official Gazette of the United States Patent and Trademark Office Patents 1278(4)

Marzabadi, M.R.; Wetzel, J.; Deleon, J.E.; Jiang, Y.; Chen, C.A.; Lu, K. 2004: Substituted anilinic piperidines as MCH selective antagonists. Official Gazette of the United States Patent and Trademark Office Patents 1281(4)

Cumming, J.G. 2003: Substituted anilino-quinazoline compounds and use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1272(3)

Cumming, J.G. 2004: Substituted anilino-quinoline compounds and use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1281(1)

Weichert, A.; Jansen, H.W.; Kleemann, H.W.; Lang, H.J.; Rutten, H. 2003: Substituted anthranilic acids, their use as a medicament or diagnostic, and medicament comprising them, and a pharmaceutical combination preparation containing a sodium/hydrogen exchange blocker. Official Gazette of the United States Patent and Trademark Office Patents 1272(3)

Ellis, W.Y. 2001: Substituted aromatic compounds for treatment of antibiotic-resistant infections. Official Gazette of the United States Patent and Trademark Office Patents 1248(5)

Lowe, John, A.IIi 2004: Substituted aromatic ethers as inhibitors of glycine transport. Official Gazette of the United States Patent and Trademark Office Patents 1285(5)

Desimone, R.W.; Blum, C.A. 2000: Substituted aryl and cycloalkyl imidazolones; a new class of GABA brain receptor ligands. Official Gazette of the United States Patent and Trademark Office Patents 1239(1)

Breault, G.A.; Oldfield, J.; Tucker, H.; Warner, P. 2004: Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists. Official Gazette of the United States Patent and Trademark Office Patents 1286(1)

Priepke, H.; Kauffmann Hefner, I.; Hauel, N.; Ries, U.; Nar, H.; Stassen, J.M.; Wienen, W. 2002: Substituted aryl and heteroaryl derivatives, their production and their use as medicines. Official Gazette of the United States Patent and Trademark Office Patents 1264(2)

Khanapure, S.P.; Garvey, D.S.; Earl, R.A.; Ezawa, M.; Fang, X.; Gaston, R.D. 2004: Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use. Official Gazette of the United States Patent and Trademark Office Patents 1280(3)

Vernier, J.M.; Mcdonald, I.A. 2001: Substituted aryl compounds useful as modulators of acetylcholine receptors. Official Gazette of the United States Patent and Trademark Office Patents 1252(2)

Holdgrun, X.; Willms, L.; Bauer, K.; Trinks, K.; Bieringer, H. 2002: Substituted aryl compounds, process for their preparation, agents containing them and their use as safeners. Official Gazette of the United States Patent and Trademark Office Patents 1264(3)

Xue, C.B.; Decicco, C.P.; Wexler, R.R. 2001: Substituted aryl hydroxamic acids as metalloproteinase inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1248(5)

Teng, M.; Duong, T.T.; Chandraratna, R.A. 2002: Substituted aryl or heteroarylamides having retinoid-like biological activity. Official Gazette of the United States Patent and Trademark Office Patents 1261(3)

Kohl, B.; Grundler, G.; Senn Bilfinger, J. 1999: Substituted arylalkythioalkythiopyridines for use in the control of helicobacter bacteria. Official Gazette of the United States Patent and Trademark Office Patents 1218(2): 1357

Quagliato, D.A.; Andrae, P.M. 2002: Substituted arylsulfides, arylsulfoxides and arylsulfones as beta-3 adrenergic receptor agonists. Official Gazette of the United States Patent and Trademark Office Patents 1263(1)

Chu, W.L.m Alex; Jensen, F.R.; Jensen, T.B.; Mcalpine, J.B.; Sokilde, B.; Santana Sorensen, A.M.; Ratnayake, S.; Jiang, J.B.; Noble, C.; Stafford, A.M. 2001: Substituted aurone derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1251(4)

Treiber, H.J.; Blank, S.; Starck, D.; Unger, L.; Teschendorf, H.J.; Wicke, K. 2001: Substituted aza and diazacycloheptane and cyclooctane compounds and their use. Official Gazette of the United States Patent and Trademark Office Patents 1245(2)

Harris, P.A.; Kuyper, L.F.; Lackey, K.E.; Veal, J.M. 2003: Substituted aza-oxindole derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1274(4)

Cox, P.J.; Bower, S.; Aldous, D.J.; Astles, P.C.; Mcgarry, D.G.; Hulme, C.; Regan, J.R.; Huang, F.C.; Djuric, S.W.; Moriarty, K.J.; Mathew, R.M.; Poli, G.B. 2004: Substituted azabicyclic compounds. Official Gazette of the United States Patent and Trademark Office Patents 1287(1)

Olesen, Preben Houlberg 1999: Substituted azacyclic compounds. Official Gazette of the United States Patent and Trademark Office Patents 1228(5)

Olesen, P.H.; Hansen, J.B. 2000: Substituted azacyclic or azabicyclic compounds. Official Gazette of the United States Patent and Trademark Office Patents 1231(2)

Olesen, Preben Houlberg 1999: Substituted azacyclic or azabicyclic compounds with affinity and selectivity for nicotinic cholinergic receptors. Official Gazette of the United States Patent and Trademark Office Patents 1225(2)

Kruger, B W.; Assmann, L.; Gayer, H.; Gerdes, P.; Heinemann, U.; Kuhnt, D.; Philipp, U.; Seitz, T.; Stetter, J.; Tiemann, R.; Dehne, H W.; Dutzmann, S.; Hanssler, G. 1999: Substituted azadioxacycloalkenes, fungicidal composition containing them, process for preparing them, and method of using them to combat fungi. Official Gazette of the United States Patent and Trademark Office Patents 1220(3): 2619

Ikunaka, M.; Shishido, Y.; Nakane, M. 2000: Substituted azaheterocyclecarboxylic acid. Official Gazette of the United States Patent and Trademark Office Patents 1236(1)

Frank, K.E.; Acker, B.A.; Ennis, M.D.; Fisher, J.F.; Fu, J.M.; Mcwhorter, W.W.J.; Morris, J.K.; Rogier, D.J.; Jacobsen, E.J. 2003: Substituted azepino indole derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1271(4)

Frank, K.E.; Acker, B.A.; Ennis, M.D.; Fisher, J.F.; Fu, J.M.; Jacobsen, E.J.; Mcwhorter, W.W.J.; Morris, J.K.; Rogier, D.J. 2003: Substituted azepino indoline derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1272(1)

Singh, R.; Reddy, A.V.N.render; Kaleta, J.; Micetich, R.G.; Whittaker, M.; Huxley, P. 2003: Substituted azetidin-2-ones as cysteine protease inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1270(4)

Hickey, D.M. Bernadette; Dhanak, D.; Leach, C.A.; Ife, R.J.; Tew, D.G. 1999: Substituted azetidin-2-ones for treatment of atherosclerosis. Official Gazette of the United States Patent and Trademark Office Patents 1228(4)

Dubowchik, G.M.; Zuev, D.S. 2003: Substituted azole derivatives as inhibitors of corticotropin releasing factor. Official Gazette of the United States Patent and Trademark Office Patents 1267(1)

Revesz, L.; Schlapbach, A. 2003: Substituted azoles. Official Gazette of the United States Patent and Trademark Office Patents 1271(3)

Rogers, T.E. 1999: Substituted b-amino acid derivatives useful as platelet aggregation inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1220(4): 3630

Thompson, M.; Vong, A.K.ok Keong; Ward, R.W.lliam 2002: Substituted benzamide derivatives and pharmaceutical compositions containing them. Official Gazette of the United States Patent and Trademark Office Patents 1258(4)

Harling, J.D.; Orlek, B.S.; Thompson, M. 2000: Substituted benzamide derivatives and their use as anticonvulsants. Official Gazette of the United States Patent and Trademark Office Patents 1237(5)

Reich, S.H.; Kephart, S.E.; Wallace, M.B.; Johnson, T.O., J. 2002: Substituted benzamide inhibitors of rhinovirus 3C protease. Official Gazette of the United States Patent and Trademark Office Patents 1257(2)

Lubisch, W.; Moller, A.; Treiber, H.J.; Knopp, M. 2002: Substituted benzamides, their production and their use as cysteine protease inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1261(3)

Bondinell, W.E.; Chan, J.A. 2003: Substituted benzanilides as CCR5 receptors ligands, antiinflammatory agents and antiviral agents. Official Gazette of the United States Patent and Trademark Office Patents 1267(1)

Medina, J.C.; Clark, D.L.; Flygare, J.A.; Rosen, T.J.; Shan, B. 2001: Substituted benzene compounds as antiproliferative and cholesterol lowering action. Official Gazette of the United States Patent and Trademark Office Patents 1250(1)

Gupta, S.; Wu, S.Y.; Tsukamoto, M.; Pulman, D.A.; Ying, B.P. 2002: Substituted benzene compounds, process for their preparation, and herbicidal and defoliant compositions containing them. Official Gazette of the United States Patent and Trademark Office Patents 1256(2)

Englert, H.; Mania, D.; Hartung, J.; Gogelein, H.; Kaiser, J.; Linz, W.; Laufer, D.W. 2000: Substituted benzenesulfonylureas and -thioureas--process for their preparation and their use as pharmaceuticals. Official Gazette of the United States Patent and Trademark Office Patents 1236(3)

Englert, H.; Mania, D.; Hartung, J.; Gogelein, H.; Kaiser, J.; Linz, W.; Wettlaufer, D. 2003: Substituted benzenesulfonylureas and -thioureas-processes for their preparation and their use as pharmaceuticals. Official Gazette of the United States Patent and Trademark Office Patents 1266(2)

Englert, H.; Mania, D.; Hartung, J.; Gogelein, H.; Kaiser, J.; Linz, W.; Wettlauper, D. 2002: Substituted benzenesulfonylureas and thioureas-process for their preparation and their use as pharmaceuticals. Official Gazette of the United States Patent and Trademark Office Patents 1254(1)

Englert, H.; Gerlach, U.; Mania, D.; Gogelein, H.; Kaiser, J. 1999: Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them. Official Gazette of the United States Patent and Trademark Office Patents 1228(1)

Phillips, Jeffrey Owen 2002: Substituted benzimidazole dosage forms and method of using same. Official Gazette of the United States Patent and Trademark Office Patents 1265(1)

Phillips, J.O. 2004: Substituted benzimidazole dosage forms and methods of using same. Official Gazette of the United States Patent and Trademark Office Patents 1280(1)

Greif, G.; Haberkorn, A.; Baasner, B.; Lieb, F.; Marhold, A.; Stolting, J. 2003: Substituted benzimidazole, the production thereof and the use thereof as means against parasitic protozoa. Official Gazette of the United States Patent and Trademark Office Patents 1270(4)

Ritzeler, O.; Stilz, H.U.; Neises, B.; Bock, W.J., J.; Walser, A.; Flynn, G.A.; Habermann, J.; Jahne, G. 2002: Substituted benzimidazoles. Official Gazette of the United States Patent and Trademark Office Patents 1256(3)

Lubisch, W.; Kock, M.; Hoger, T.; Schult, S.; Grandel, R.; Muller, R. 2002: Substituted benzimidazoles and their use as parp inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1262(2)

Assmann, L.; Marhold, A.; Dehne, H.W.; Dutzmann, S.; Erdelen, C.; Stenzel, K. 1999: Substituted benzimidazoles for pest control. Official Gazette of the United States Patent and Trademark Office Patents 1225(1)

Hofmeister, A.; Heinelt, U.; Lang, H.J.; Bleich, M.; Wirth, K.; Gekle, M. 2004: Substituted benzimidazoles, processes for their preparation, their use as medicaments, and medicaments comprising them. Official Gazette of the United States Patent and Trademark Office Patents 1279(1)

Greif, G.; Haberkorn, A.; Baasner, B.; Lieb, F.; Marhold, A. 2003: Substituted benzimidazoles, production and use thereof as agents for combating parasitic protozoas. Official Gazette of the United States Patent and Trademark Office Patents 1274(3)

Venkatesan, A.M. 2000: Substituted benzo dioxines as antiobesity agents. Official Gazette of the United States Patent and Trademark Office Patents 1236(1)

Antane, S.A.; Butera, J.A.; Lennox, J.R. 2001: Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers. Official Gazette of the United States Patent and Trademark Office Patents 1250(2)

Dankulich, W.P.; Mcgarry, D.G.; Burns, C.; Gallagher, T.F.; Volz, F.A. 2003: Substituted benzoheteroaryl compounds. Official Gazette of the United States Patent and Trademark Office Patents 1269(1)

Wakabayashi, H.; Ikunaka, M. 2001: Substituted benzolactam compounds as substance P antagonists. Official Gazette of the United States Patent and Trademark Office Patents 1242(5)

Carter, J.S.; Obukowicz, M.G.; Devadas, B.; Talley, J.J.; Brown, D.L.; Graneto, M.J.; Bertenshaw, S.R.; Rogier, D.J.; Nagarajan, S.R.; Hanau, C.E.; Hartmann, S.J.; Ludwig, C.L.; Metz, S.; Korte, D.E. 2000: Substituted benzopyran analogs for the treatment of inflammation. Official Gazette of the United States Patent and Trademark Office Patents 1235(3)

Bell, D.A.; Cox, P.J.; Thompson, M.; Turner, G. 2002: Substituted benzopyran derivatives and their use as anticonvulsants. Official Gazette of the United States Patent and Trademark Office Patents 1258(4)

Carter, J.S.; Obukowicz, M.G.; Devadas, B.; Talley, J.J.; Brown, D.L.; Graneto, M.J.; Bertenshaw, S.R.; Rogier, D.J.Jr; Nagarajan, S.R.; Hanau, C.E.; Hartman, S.J.; Ludwig, C.L.; Metz, S.; Korte, D.E. 2004: Substituted benzopyran derivatives for the treatment. Official Gazette of the United States Patent and Trademark Office Patents 1287(3)

Carter, J.S.; Obukowicz, M.G.; Devadas, B.; Talley, J.J.; Brown, D.L.; Graneto, M.J.; Bertenshaw, S.R.; Rogier, D.J.; Nagarajan, S.R.; Hanau, C.E.; Hartmann, S.J.; Ludwig, C.L.; Metz, S. 2000: Substituted benzopyran derivatives for the treatment of inflammation. Official Gazette of the United States Patent and Trademark Office Patents 1232(1)

Gorycki, P.D.; Annan, B.W.; Kuo, G.Y. 1999: Substituted benzopyrans. Official Gazette of the United States Patent and Trademark Office Patents 1225(3)

Flohr, A.; Jakob Roetne, R.; Norcross, R.D.; Riemer, C. 2004: Substituted benzothiazole amide derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1281(4)

Heistracher, E.; Hamprecht, G.; Menke, O.; Schaefer, P.; Zagar, C.; Westphalen, K O.; Misslitz, U.; Walter, H. 1999: Substituted benzothiazols with herbicidal action. Official Gazette of the United States Patent and Trademark Office Patents 1220(5): 4564

Viaud, M.C.; Guillaumet, G.; Daubos, P.; Bennejean, C.; Delagrange, P.; Renard, P. 2003: Substituted benzoxazine and benzothiazine compounds. Official Gazette of the United States Patent and Trademark Office Patents 1274(3)

Vianello, P.; Bandiera, T. 2004: Substituted benzoxazines as integrin antagonists. Official Gazette of the United States Patent and Trademark Office Patents 1283(3)

Clark, D.E.; Eastwood, P.R.; Harris, N.V.; Mccarthy, C.; Morley, A.D.; Pickett, S.D. 2003: Substituted benzoxazole compounds. Official Gazette of the United States Patent and Trademark Office Patents 1272(3)

Malamas, M.S.; Mcdevitt, R.E.; Gunawan, I.; Manas, E.S.; Collini, M.D. 2004: Substituted benzoxazoles as estrogenic agents. Official Gazette of the United States Patent and Trademark Office Patents 1286(3)

Nagasawa, M.; Sato, K.; Kurimoto, T.; Ueki, S. 2000: Substituted benzoylaminothiazole derivatives and drugs containing the same. Official Gazette of the United States Patent and Trademark Office Patents 1238(3)

Lang, H J.; Weicher, A.; Kleemann, H W.; Schwark, J R.; Scholz, W.; Schwark, J R.; Scholz, W.; Albus, U. 1999: Substituted benzoylguanidines, process for their preparation, their use as a pharmaceutical as inhibitors of the cellular NA+/H+ exchange or as a diagnostic, and pharmaceutical containing them. Official Gazette of the United States Patent and Trademark Office Patents 1219(1): 569-570

Galey, Jean Baptiste 1999: Substituted benzyl derivatives of polyalkylene polyamines and their use in cosmetic and pharmaceutical compositions. Official Gazette of the United States Patent and Trademark Office Patents 1223(2)

Grammenos, W.; Sauter, H.; Bayer, H.; Grote, T.; Gypser, A.; Kirstgen, R.; Muller, B.; Ptock, A.; Rohl, F.; Gotz, R.; Lorenz, G.; Ammermann, E.; Strathmann, S.; Harries, V. 2001: Substituted benzyl oximino compounds. Official Gazette of the United States Patent and Trademark Office Patents 1253(2)

Satake, K.; Shishido, Y.; Wakabayashi, H. 2003: Substituted benzylaminopiperidine compounds. Official Gazette of the United States Patent and Trademark Office Patents 1266(2)

Sperl, G.; Gross, P.; Brendel, K.; Pamukcu, R.; Piazza, G.A. 2000: Substituted benzylidene indenyl formamides, acetamides and propionamides. Official Gazette of the United States Patent and Trademark Office Patents 1234(3)

Kleemann, H.W.; Brendel, J.; Schwark, J.R.; Weichert, A.; Lang, H.J.; Albus, U.; Scholz, W. 2000: Substituted benzyloxy-carbonylguanidines, a process for their preparation, their use as a medicament or diagnostic, and a medicament containing them. Official Gazette of the United States Patent and Trademark Office Patents 1231(2)

Fujimori, S.; Murakami, K.; Tsunoda, M. 2003: Substituted benzylthiazolidine-2,4-dione derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1269(2)

Reddy, E.P.; Reddy, M.V.R. 2003: Substituted benzylthioacetic acids and esters. Official Gazette of the United States Patent and Trademark Office Patents 1276(1)

Kanamaru, Y.; Hirota, H.; Shibata, A.; Komoto, T.; Naito, H.; Tachibana, K.; Ohtsuka, M.; Ishii, F.; Sato, S. 1999: Substituted benzylurea derivatives and medicine containing the same. Official Gazette of the United States Patent and Trademark Office Patents 1224(2)

Ritzeler, O.; Castro, A.; Grenier, L.; Soucy, F.; Hancock, W.W.; Mazdiyashi, H.; Palombella, V.; Adams, J. 2003: Substituted beta carbolines. Official Gazette of the United States Patent and Trademark Office Patents 1274(5)

Aho, P.; Backstrom, R.; Koponen, A.; Linden, I.B.; Lotta, T.; Lonnberg, K.; Pippuri, A.; Pohto, P. 2001: Substituted beta diketones and their use. Official Gazette of the United States Patent and Trademark Office Patents 1244(2)

Stolle, Andreas; Antonicek, Horst Peter; Lensky, Stephen; Voerste, Arnd; Muller, Thomas; Baumgarten, Jorg; Von Dem Bruch, Karsten; Muller, Gerhard; Stropp, Udo; Horvath, Ervin; De Vry, Jean Marie Viktor; Schreiber, Rudy 2002: Substituted beta,gamma-anellated lactones. Official Gazette of the United States Patent and Trademark Office Patents 1261(2)

Durette, P.L.; Hagmann, W.K.; Kopka, I.E.; Maccoss, M.; Mills, S.G.; Mumford, R.A.; Magriotis, P.A. 2003: Substituted beta-alanine derivatives as cell adhesion inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1276(2)

Astles, P.C.; Harris, N.V.; Morley, A.D. 2002: Substituted beta-alanines. Official Gazette of the United States Patent and Trademark Office Patents 1256(1)

Craig, R.A.; Henkin, J.; Kawai, M.; Lynch, L.M.; Patel, J.; Sheppard, G.S.; Wang, J. 2001: Substituted beta-amino acid inhibitors of methionine aminopeptidase-2. Official Gazette of the United States Patent and Trademark Office Patents 1247(1)

Burns, C.J.; Labaudiniere, R.; Condon, S.; Groneberg, R.D.; Mathew, R.M.; Salvino, J.M. 2001: Substituted beta-thiocarboxylic acids. Official Gazette of the United States Patent and Trademark Office Patents 1251(4)

Clark, D.E.; Eastwood, P.R.; Harris, N.V.; Mccarthy, C.; Morley, A.D.; Pickett, S.D. 2003: Substituted bicyclic compounds. Official Gazette of the United States Patent and Trademark Office Patents 1270(2)

Fliri, A.F.anz Joseph; Butler, T.W.lliam 2002: Substituted bicyclic derivatives for treating central nervous system disorders. Official Gazette of the United States Patent and Trademark Office Patents 1257(3)

Kath, J.C.; Tom, N.J.; Liu, Z.; Cox, E.D.; Morris, J.; Bhattacharya, S.K. 2001: Substituted bicyclic derivatives useful as anticancer agents. Official Gazette of the United States Patent and Trademark Office Patents 1250(1)

Schwark, J.R.; Kleemann, H.W.; Lang, H.J.; Weichert, A.; Scholz, W.; Albus, U. 2000: Substituted bicyclic heteroaroylguanidines, a process for their preparation, their use as a medicament or a diagnostic agent, and a medicament containing them. Official Gazette of the United States Patent and Trademark Office Patents 1236(4)

Clark, D.E.; Eastwood, P.R.; Harris, N.V.; Mccarthy, C.; Morley, A.D.; Pickett, S.D. 2004: Substituted bicyclic heteroaryl compounds and their use as integrin antagonists. Official Gazette of the United States Patent and Trademark Office Patents 1280(3)

Dhaninaut, A.; Poissonnet, G.; Canft, E.; Lonchampt, M. 1999: Substituted biphenyl compounds. Official Gazette of the United States Patent and Trademark Office Patents 1220(1): 544-545

Reitz, D.B.; Li, J.J.; Norton, M.B. 2004: Substituted biphenyl compounds for the treatment of inflammation. Official Gazette of the United States Patent and Trademark Office Patents 1278(2)

Lantzsch, R.; Marhold, A.; Kramer, W.; Erdelen, C.; Wachendorff Neumann, U.; Turberg, A.; Mencke, N. 1999: Substituted biphenyloxazolines. Official Gazette of the United States Patent and Trademark Office Patents 1227(3)

Schoen, W.R.; Ladouceur, G.H.; Cook, J.H.II.L.ase, T.G.; Wolanin, D.J.; Kramss, R.H.; Hertzog, D.L.; Osterhout, M.H. 2001: Substituted biphenyls. Official Gazette of the United States Patent and Trademark Office Patents 1245(3)

Murugesan, N.; Barrish, J.C.; Lloyd, J. 2000: Substituted biphenylsulfonamide endothelin antagonists. Official Gazette of the United States Patent and Trademark Office Patents 1235(4)

Murugesan, N.; Barrish, J.C.; Lloyd, J. 2001: Substituted biphenysulfonamide endothelin antagonists. Official Gazette of the United States Patent and Trademark Office Patents 1249(1)

Bondinell, William E.; Reader, Valerie A.; Fu Ku, Thomas Wen 2001: Substituted bis-acridines and related compounds as CCR5 receptor ligands, anti-inflammatory agents and anti-viral agents. Official Gazette of the United States Patent and Trademark Office Patents 1247(1)

Lu, Z.; Tata, J.R.; Cheng, K.; Wei, L.; Chan, W.W.S.; Butler, B.; Schleim, K.D.; Jacks, T.M.; Hickey, G.; Patchett, A.A. 2002: Substituted bridged phenyl piperidines Orally active growth hormone. Abstracts of Papers American Chemical Society 224(1-2): MEDI 371

Cabri, W.; Candiani, I.; Bedeschi, A.; Zarini, F.; Penco, S. 1999: Substituted camptothecin derivatives and process for their preparation. Official Gazette of the United States Patent and Trademark Office Patents 1218(1): 414-415

Yoshikawa, Y.kihiro; Tomiya, Kanji; Tomura, Naofumi; Katsuta, Hiroyuki; Takahashi, Osamu; Inami, Shunichi; Yanase, Y.ji; Kishi, Junro; Kawashima, Hideo 1999: Substituted carboxanilide derivative and plant disease control agent comprising same as active ingredient. Official Gazette of the United States Patent and Trademark Office Patents 1223(4)

Potter, G.A.; Butler, P.C.; Wanogho, E. 2004: Substituted chalcones as therapeutic compounds. Official Gazette of the United States Patent and Trademark Office Patents 1286(1)

Abraham, D.J.; Joshi, G.S.; Hoffman, S.J.; Grella, M.; Danso Danquah, R.; Yousseff, A.; Safo, M.; Kulkarni, S. 2002: Substituted chiral allosteric hemoglobin modifiers. Official Gazette of the United States Patent and Trademark Office Patents 1264(4)

Berg, S.; Linderberg, M.; Ross, S.B.; Thorberg, S.O.; Ulff, B. 2002: Substituted chroman derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1258(2)

Schwark, J R.; Brendel, J.; Kleemann, H W.; Lang, H.J.; Weichert, A.; Albus, U.; Scholz, W. 1999: Substituted cinnamic acid guanidides, a process for their preparation, their use as medicaments or diagnostic agents and medicaments comprising them. Official Gazette of the United States Patent and Trademark Office Patents 1220(3): 2585

Hofmeister, A.; Hropot, M.; Heinelt, U.; Bleich, M.; Lang, H.J.chen 2002: Substituted cinnamic, acid guanidides, process for their preparation, their use as a medicament, and medicament comprising them. Official Gazette of the United States Patent and Trademark Office Patents 1259(1)

Sperl, G.; Gross, P.; Brendel, K.; Piazza, G.; Pamukcu, R. 2000: Substituted condensation products of 1H-indenyl-hydroxyalkanes with aldehydes for neoplasia. Official Gazette of the United States Patent and Trademark Office Patents 1231(4)

Sperl, G.J.; Gross, P.; Brendel, K.; Piazza, G.A.; Pamukcu, R. 2000: Substituted condensation products of N-benzyl-3-idenylacetamides with heterocyclic aldehydes for neoplasia. Official Gazette of the United States Patent and Trademark Office Patents 1241(4)

Sperl, G.J.; Gross, P.; Brendel, K.; Piazza, G.A.; Pamukcu, R. 2003: Substituted condensation products of N-benzyl-3-indenylacentamides with heterocyclic aldehydes for neoplasia. Official Gazette of the United States Patent and Trademark Office Patents 1273(4)

Sperl, G.J.; Gross, P.; Brendel, K.; Piazza, G.A.; Pamukeu, R. 2002: Substituted condensation products of N-benzyl-3-indenylacetamides with heterocyclic aldehydes for neoplasia. Official Gazette of the United States Patent and Trademark Office Patents 1260(5)

Sperl, G.J.; Gross, P.; Brendel, K.; Piazza, G.A.; Pamukcu, R. 1999: Substituted condensation products of n-benzyl-3-indenyl acetamides with heterocyclic aldehydes. Official Gazette of the United States Patent and Trademark Office Patents 1226(1)

Hagmann, W.K.; Doherty, G.A.; Shah, S. 2002: Substituted cyclic amidine derivatives as inhibitors of cell adhesion. Official Gazette of the United States Patent and Trademark Office Patents 1264(3)

Horwell, D.C.; Bryans, J.S.; Kneen, C.O.; Morrell, A.I.; Ratcliffe, G.S.; Hartenstein, J. 2000: Substituted cyclic amino acids as pharmaceutical agents. Official Gazette of the United States Patent and Trademark Office Patents 1237(3)

Lam, Patrick Yuk Sun; Jadhav, Prabhakar Kondaji; Eyermann, Charles Joseph; Hodge, Carl Nicholas; De Lucca, George Vincent; Rodgers, James David 2003: Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1266(1)

Cook, P.D.; An, H.; Haly, B.; Wang, T. 2001: Substituted cyclic compounds and mixtures comprising same. Official Gazette of the United States Patent and Trademark Office Patents 1243(3)

Lesieur, D.; Klupsch, F.; Guillaumet, G.; Viaud, M.C.; Langlois, M.; Bennejean, C.; Renard, P.; Delagrange, P. 2003: Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them. Official Gazette of the United States Patent and Trademark Office Patents 1273(2)

Kluender, H.C.; Benz, G.H.H.H.; Combs, K.J.; Dixon, B.R.; Vanzandet, M.C.; Wilhelm, S.M.; Wolanin, D.J.; Wood, J.E.; Schneider, S. 1999: Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1219(4): 3374-3375

Gayer, H.; Gerdes, P.; Tiemann, R.; Dutzmann, S.; Stenzel, K. 2002: Substituted cycloalkenes and their use as microbices, especially as fungicides. Official Gazette of the United States Patent and Trademark Office Patents 1261(3)

Gayer, H.; Gerdes, P.; Tiemann, R.; Dutzmann, S.; Stenzel, K. 2000: Substituted cycloalkenes, process of preparing them and method of using them as pesticides. Official Gazette of the United States Patent and Trademark Office Patents 1240(3)

Desimone, R.W.; Rosewater, D.L. 2001: Substituted cycloalkyl-4-Oxonicotinic carboxamides; gaba brain receptor ligands. Official Gazette of the United States Patent and Trademark Office Patents 1243(4)

Markl, M.; Schaper, W.; Knauf, W.; Sanft, U.; Kern, M.; Bonin, W.; Linkies, A.; Reuschling, D.B. 1999: Substituted cycloalkylamino and cycloalkoxy heterocycles, process for preparing them and their use as pesticides. Official Gazette of the United States Patent and Trademark Office Patents 1220(5): 4590-4591

Yang, M.G.; Liu, H. 2004: Substituted cycloalkyls as inhibitors of a beta protein production. Official Gazette of the United States Patent and Trademark Office Patents 1280(5)

Takemura, M.; Takahashi, H.; Sugita, K.; Miyauchi, R. 2002: Substituted cyclobutylamine derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1262(2)

Belliotti, T.R.; Kesten, S.R.; Pugsley, T.A.; Wustrow, D.J. 1999: Substituted cyclohexylamines as central nervous systems agents. Official Gazette of the United States Patent and Trademark Office Patents 1228(1)

Babu, Y.S.; Chand, P.; Montgomery, J.A. 2003: Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1270(2)

Babu, Y.S.; Chand, P.; Montgomery, J.A. 2002: Substituted cyclopentane compounds useful as neuraminidase inhibitors. Official Gazette of the United States Patent and Trademark Office Patents 1259(4)

Ross, R.; Fujimoto, T.T.; Shaber, S.H. 2000: Substituted cyclopropyl phenoxymethyl phenyl carbamates and their use as fungicides. Official Gazette of the United States Patent and Trademark Office Patents 1231(2)

Hartmann, M.; Kremminger, P.; Blaschke, H.; Stimmeder, D.; Fellier, H.; Rovenszky, F. 2001: Substituted derivatives of benzosulphonamides as inhibitors of the enzyme cyclooxygenase II. Official Gazette of the United States Patent and Trademark Office Patents 1251(1)

Johnson, S.G.; Rivero, R.A. 2003: Substituted diamine derivatives useful as motilin antagonists. Official Gazette of the United States Patent and Trademark Office Patents 1266(4)

Janssen, P.A.J.; Heeres, J.; Moereels, H.E.L.; Kukla, M.J.; Ludovici, D.W. 2002: Substituted diamino-1,3,5-triazine derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1257(5)

Thorwart, W.; Schwab, W.; Schudok, M.; Haase, B.; Neises, B.; Billen, G. 2000: Substituted diaminocarboxylic acids. Official Gazette of the United States Patent and Trademark Office Patents 1241(2)

Song, T.K.; Teng, M.; Chandraratna, R.A. 2002: Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity. Official Gazette of the United States Patent and Trademark Office Patents 1262(4)

Song, T.K.; Teng, M.; Chandraratna, R.A. 2003: Substituted diaryl or diheteroaryl methans, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity. Official Gazette of the United States Patent and Trademark Office Patents 1277(2)

Connor, D.T.; Hu, L.Y.; Malone, T.C.; Rafferty, M.F.; Roth, B.D.; Ryder, T.R.; Sercel, A.D.; Song, Y. 2002: Substituted diarylalkyl amides as calcium channel antagonists. Official Gazette of the United States Patent and Trademark Office Patents 1263(1)

Robinson, L.; Villar, H.O. 2003: Substituted diarylureas as stimulators for Fas-mediated apoptosis. Official Gazette of the United States Patent and Trademark Office Patents 1267(4)

Zaworotko, M.J.; Iyer, S.S. 1999: Substituted diazaanthracene compounds having pharmaceutical utility. Official Gazette of the United States Patent and Trademark Office Patents 1228(5)

D.P.ulis, T.; Lovinger, D.M.; Martin, P. 2004: Substituted dicinnamoylquinides and their use in augmentation of adenonsine function. Official Gazette of the United States Patent and Trademark Office Patents 1279(3)

Martin, T.; Ulrich, W.R.diger 2000: Substituted dihydrobenzofuran-based phosphodiesterase 4 inhibitors useful for treating airway disorders. Official Gazette of the United States Patent and Trademark Office Patents 1233(4)

Burns, C.J.; Dankulich, W.P.; Mcgarry, D.G.; Volz, F.A. 2003: Substituted dihydrobenzofurans and benzopyrans. Official Gazette of the United States Patent and Trademark Office Patents 1272(5)

Depreux, P.; Yous, S.; Cheve, G.; Guillaumet, G.; Viaud, M.C.; Larraya, C.; Bennejean, C.; Delagrange, P.; Renard, P.; Descamps Francois, C. 2001: Substituted dimeric compounds. Official Gazette of the United States Patent and Trademark Office Patents 1251(5)

Doherty, A.M.; Kaltenbronn, J.S.; Leonard, D.; Quin, J.; Scholten, J.D. 1999: Substituted dinaphthylmethyl and diheteroarylmethylacetyl histidine inhibitors of protein farnesyltransferase. Official Gazette of the United States Patent and Trademark Office Patents 1229(4)

Berger, M.L.; Poehler, T.; Rebernik, P.; Noe, C.R. 2000: Substituted dipeptides synthesized via combinatorial chemistry as highly polyamine- and proton-sensitive NMDA receptor blockers. European Journal of Neuroscience 12(Suppl 11): 393

Singh, R.; Goff, D.; Lu, H.; Issankani, S.D.; Sun, T. 2004: Substituted diphenyl heterocycles useful for treating HCV infection. Official Gazette of the United States Patent and Trademark Office Patents 1284(1)

Brugnara, C.; Halperin, J.; Fluckiger, R.; Bellott, E.M.; Lombardy, R.J.; Clifford, J.J.; Gao, Y.D.; Haidar, R.M.; Kelleher, E.W.; Moussa, A.M.; Sachdeva, Y.P.; Sun, M.; Taft, H.N. 2000: Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment of prevention of diseases characterized by abnormal cell proliferation. Official Gazette of the United States Patent and Trademark Office Patents 1232(4)

Kramer, W.; Kraatz, U.; Lantzsch, R.; Marhold, A.; Erdelen, C.; Wachendorff Neumann, U.; Turberg, A.; Mencke, N. 2002: Substituted diphenyl oxazolin derivatives with insecticidal effect. Official Gazette of the United States Patent and Trademark Office Patents 1260(1)

Schmidt, W.; Wingen, R. 2004: Substituted fluoroaromatics, process for preparing them and their use. Official Gazette of the United States Patent and Trademark Office Patents 1278(2)

Ashbrook, C.D. 2000: Substituted furanones, compositions and antiarthritic use. Official Gazette of the United States Patent and Trademark Office Patents 1234(4)

Fujita, T.; Wada, K.; Fujiwara, T. 2002: Substituted fused heterocyclic compound. Official Gazette of the United States Patent and Trademark Office Patents 1261(2)

Bantick, J.; Cooper, M.; Thorne, P.; Perry, M. 2004: Substituted fused pyridazinone compounds; composition and use thereof. Official Gazette of the United States Patent and Trademark Office Patents 1285(1)

Maynard, G.; Xie, L.; Rachwal, S. 2004: Substituted fused pyrroleimines and pyrazoleimines. Official Gazette of the United States Patent and Trademark Office Patents 1283(1)

Bryans, J.S.; Horwell, D.C.; Kneen, C.O.; Thorpe, A.J.; Wustrow, D.J. 2000: Substituted gamma aminobutyric acids as pharmaceutical agents. Official Gazette of the United States Patent and Trademark Office Patents 1240(4)

Shen, Y.; Burgoyne, D.L.; Lauener, R.W.; Zhou, Y.; Rebstein, P.J.; Abraham, S.D.M. 2004: Substituted gamma-phenyl-DELTA-lactams and uses related thereto. Official Gazette of the United States Patent and Trademark Office Patents 1285(1)

Shen, Y.; Burgoyne, D.L.; Lauener, R.W.; Zhou, Y.; Rebstein, P.J.; Abraham, S.D.M. 2002: Substituted gamma-phenyl-DELTA-lactones and analogs thereof and uses related thereto. Official Gazette of the United States Patent and Trademark Office Patents 1263(1)

Germann, T.; Frosch, S.; Wade, E.; Buschmann, H.; Zimmer, O. 2003: Substituted glutarimides and their use as inhibitors of IL-12 production. Official Gazette of the United States Patent and Trademark Office Patents 1277(1)

Wagner, K.; Erdelen, C.; Andersch, W.; Wachendorff Neumann, U.; Turberg, A.; Mencke, N. 2003: Substituted guanidine derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1277(4)

Kitano, M.; Yuri, M.; Ohashi, N. 2004: Substituted guanidine derivatives. Official Gazette of the United States Patent and Trademark Office Patents 1282(2)

Kitano, M.; Ohashi, N. 2002: Substituted guanidine derivatives and process for producing the same. Official Gazette of the United States Patent and Trademark Office Patents 1257(2)

Kitano, M.; Ohashi, N. 2001: Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof. Official Gazette of the United States Patent and Trademark Office Patents 1249(1)

Mogensen, J.P.; Hansen, J.B.; Tagmose, T.M. 2000: Substituted guanidines and diaminonitroethenes, their preparation and use. Official Gazette of the United States Patent and Trademark Office Patents 1240(2)

Jeppesen, L.; Bury, P.S.; Sauerberg, P. 2002: Substituted hetero-polycyclic compounds as PPARalpha and PPARgamma activators. Official Gazette of the United States Patent and Trademark Office Patents 1263(4)

Filla, S.A.; Krushinski, J.H.Jr; Schaus, J.M. 1999: Substituted heteroaromatic 5-HT-1-F agonists. Official Gazette of the United States Patent and Trademark Office Patents 1219(4): 3356-3357

Robichaud, Albert J.; Lee, Taekyu; Deng, Wei; Mitchell, Ian S.; Yang, Michael Guang; Haydar, Simon; Chen, Wenting; Mc Clung, Christopher D.; Calvello, Emilie J.B.; Zawrotny, David M. 2003: Substituted heterocycle fused gamma-carbolines. Official Gazette of the United States Patent and Trademark Office Patents 1269(4)