EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment of prevention of diseases characterized by abnormal cell proliferation



Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment of prevention of diseases characterized by abnormal cell proliferation



Official Gazette of the United States Patent & Trademark Office Patents 1232(4), Mar 28



The present invention provides substituted 3,3-diphenyl indanone, indane and indole compounds, as well as analogues thereof, which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell proliferation in situ as a therapeutic approach towards the treatment or prevention of diseases characterized by abnormal cell proliferation, such as cancer.

(PDF emailed within 1 workday: $29.90)

Accession: 035790976

Download citation: RISBibTeXText



Related references

Triaryl methane compounds and analogues thereof useful for the treatment or prevention of sickle cell disease or diseases characterized by abnormal cell proliferation. Official Gazette of the United States Patent & Trademark Office Patents 1231(4), Feb 22, 2000

Substitute 11-phenyl-dibenzazepine compounds useful for the treatment or prevention of diseases characterized by abnormal cell proliferation. Official Gazette of the United States Patent & Trademark Office Patents 1268(3), Mar 18, 2003

Methyl substituted propyl-substituted pentamethyl indane derivatives processes for producing same and perfumery uses thereof. Official Gazette of the United States Patent & Trademark Office Patents 1183(4): 2219, Feb 27, 1996

Substituted piperidinobutyl nitrogen-containing heterocyclic compounds and analogues thereof as neurokinin antagonists. Official Gazette of the United States Patent & Trademark Office Patents 1209(2): 1439, April 14, 1998

Diphenyl-substituted heterocycles with 6-membered ring, processes for the preparation thereof and the use thereof as medicaments. Official Gazette of the United States Patent & Trademark Office Patents 1246(4), May 22, 2001

Indole derivatives and their use for the treatment of malignant and other diseases based on pathological cell proliferation. Official Gazette of the United States Patent & Trademark Office Patents 1259(3), June 18, 2002

Method for manufacturing of 1,4-dihydropyridines, novel N-substituted bicyclic 4-hydropyridines, and novel bicyclic N-substituted 4,5-dihydrophyridines, intermediates useful in the manufacture thereof, and the compounds thereof which have potential activi. Official Gazette of the United States Patent & Trademark Office Patents 1208(1): 507-508, March 3, 1998

The microsomal oxidation of indane to indanol 1 and indanone 1. Pharmacologist 10(2): 202, 1968

Treatment of arthropathies with vanadate compounds or analogues thereof. Official Gazette of the United States Patent & Trademark Office Patents 1219(3): 2430, Feb 16, 1999

Substituted phenylacrylonitrile compounds and compositions thereof for the treatment of disease. Official Gazette of the United States Patent & Trademark Office Patents 1228(2), Nov 9, 1999

Drug treatment of diseases characterized by abnormal movements. Proceedings of the Royal Society of Medicine 66(9): 871-873, 1973

Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseases. Official Gazette of the United States Patent & Trademark Office Patents 1248(3), July 17, 2001

Antiparasitic agents part xiii. synthesis and anthelmintic activity of 6 2 4 dioxoquinazolin 3 yl 1 substituted 9h pyrido 3 4 b indole and 8 2 4 dioxoquinazolin 3 yl 1 substituted 9h pyrido 3 4 b indole 6 2 methyl 5 acetamidobenzimidazol 1 yl 1 substituted 9h pyrido 3 4 b indole and 8 2 methyl 5 acetamidobenzimidazol 1 yl 1 substituted 9h pyrido 3 4 b indole and 6 2 carbomethoxyamino 5 n n' dicarbomethoxyguanidinobenzimidazol 1 yl 1 phenyl 9h pyrido 3 4 b indole. Indian Journal of Chemistry Section B Organic Chemistry Including Medicinal Chemistry 29(9): 848-854, 1990

QSAR analyses of the substituted indanone and benzylpiperidine rings of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase. Journal of Medicinal Chemistry 35(3): 584-589, 1992

Treatment of proliferative disorders, metastasaes, and drug resistant tumors with vanadate of compounds and derivatives or analogues thereof. Official Gazette of the United States Patent & Trademark Office Patents 1217(1): 417, Dec 1, 1998