+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The Role Of Dryness Symptoms In Discontinuation Of Wear And Unscheduled Lens Removals In Extended Wear Of Silicone Hydrogel Lenses



The Role Of Dryness Symptoms In Discontinuation Of Wear And Unscheduled Lens Removals In Extended Wear Of Silicone Hydrogel Lenses



ARVO Annual Meeting Abstract Search and Program Planner: Abstract No. 3088



Purpose: To study the role of dryness in discontinuation of lens wear and unscheduled lens removals in subjects wearing monthly and weekly extended wear (EW) lenses. Methods: In a year-long randomized controlled open-label clinical trial, 658 subjects were randomized to lotrafilcon A lenses (Focus(R) NIGHTDELTAAY, CIBA Vision) or etafilcon A lenses (n= 681, AcuVue, Johnson & Johnson). The lotrafilcon A group wore lenses up to 30 nights EW and etafilcon A wearers wore lenses up to 6 nights EW. Subjective symptoms were collected at all visits. Results: Among subjects who completed the year long trial, 19.8% of the silicone hydrogel wearers (n=483) reported symptoms of dryness compared with 24.2% of those wearing disposable lenses (n=579, p=0.093, Chi-square). For subjects who discontinued the study, 13.4% of the discontinued lotrafilcon A wearers (n=175) and 22.1% of the discontinued etafilcon A lens wearers (n=102) reported symptoms of dryness (p=0.042, Chi-square). When asked reasons for unscheduled overnight lens removals, etafilcon A wearers cited dryness as the reason for removal significantly more often, reporting 720 unscheduled removals due to dryness compared to 236 unscheduled removals due to dryness for lotrafilcon A wearers (p=0.02, Student's t-test). Conclusion: Symptoms of dryness play an important role in EW. These data show that symptoms of dryness are less frequent among wearers of lotrafilcon A lenses (monthly EW wearing schedule) compared with wearers of etafilcon A lenses (weekly EW wearing schedule). Subjects wearing lotrafilcon A lenses were also much less likely report dryness as the reason for discontinuing lens wear or for unscheduled lens removals compared to wearers of etafilcon A lenses.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 035849866

Download citation: RISBibTeXText

DOI: 10.1097/00006324-200112001-00357


Related references

Prevalence of ocular surface symptoms, signs, and uncomfortable hours of wear in contact lens wearers: the effect of refitting with daily-wear silicone hydrogel lenses (senofilcon a). Eye and Contact Lens 32(6): 281-286, 2006

Short-term adaptation of the human corneal endothelium to continuous wear of silicone hydrogel (lotrafilcon A) contact lenses after daily hydrogel lens wear. Optometry and Vision Science 82(6): 473-480, 2005

Seven-day extended wear and 30-day continuous wear of high oxygen transmissibility soft silicone hydrogel contact lenses: a randomized 1-year study of 504 patients. Clao Journal 27(3): 125-136, 2001

Differences in Dry Eye Questionnaire Symptoms in Two Different Modalities of Contact Lens Wear: Silicone-Hydrogel in Daily Wear Basis and Overnight Orthokeratology. Biomed Research International 2016: 1242845, 2016

Long-term clinical results: 3 years of up to 30-night continuous wear of lotrafilcon A silicone hydrogel and daily wear of low-Dk/t hydrogel lenses. Eye and Contact Lens 33(2): 74-80, 2007

Extended-wear silicone hydrogel soft contact lenses in the management of moderate to severe dry eye signs and symptoms secondary to graft-versus-host disease. Eye and Contact Lens 33(3): 144-147, 2007

Complications and symptoms in disposable extended wear lenses compared with conventional soft daily wear and soft extended wear lenses. Clao Journal 19(1): 31-39, 1993

Duration of discontinuation from silicone hydrogel extended wear due to adverse responses. ARVO Annual Meeting Abstract Search and Program Planner : Abstract No 3706, 2003

The effect of lens wear on refractive index of conventional hydrogel and silicone-hydrogel contact lenses: a comparative study. Contact Lens and Anterior Eye 31(2): 89-94, 2007

Personal experience with hydrogel and silicone extended wear lenses. CLAO Journal 11(2): 136-137, 1985

Comparing goblet cell densities in patients wearing disposable hydrogel contact lenses versus silicone hydrogel contact lenses in an extended-wear modality. Eye and Contact Lens 29(4): 241-244, 2003

Microbial keratitis associated with extended wear of silicone hydrogel contact lenses. British Journal of Ophthalmology 86(3): 355-357, 2002

Bacterial populations on 30-night extended wear silicone hydrogel lenses. Clao Journal 27(1): 30-34, 2001

Ocular surface sensitivity following discontinuation of low dk extended contact lens wear and refitting with high dk extended wear. ARVO Annual Meeting Abstract Search and Program Planner : Abstract No 3705, 2003

Improving contact-lens related dryness symptoms with silicone hydrogel lenses. Optometry and Vision Science 85(8): 778-784, 2008