The SAFE study: saline vs. albumin for fluid resuscitation in the critically ill
Finfer, S.; Norton, R.; Bellomo, R.; Boyce, N.; French, J.; Myburgh, J.
Vox Sanguinis 87 Suppl. 2: 123-131
2004
ISSN/ISBN: 0042-9007
PMID: 15209896
DOI: 10.1111/j.1741-6892.2004.00468.x
Accession: 035850067
Historical studies, using Northern blot hybridization, RT-PCR and cDNA library construction have demonstrated the presence of a variety of mRNA molecules in platelets. The development of microarray technology has allowed further characterization of the transcripts represented in the platelet transcriptome. In this review, these studies will be summarized and their findings in relation to the study of platelet function and the identification of disease risk genes discussed.