Treatment and prevention of neoplasms with salts of aminoimidazole carboxamide and 5-amino or substituted amino 1,2,3-triazoles

Salts of aminoimidazole carboxamide and 5 amino or substituted amino 1,2,3-triazole, induce apoptosis, inhibit DNA synthesis and control cyclooxygenase activity. Official Gazette of the United States Patent & Trademark Office Patents 1246(5), May 29, 2001

Treatment and prevention of primary and metastatic neoplasms with salts of aminoimidazole carboxamide. Official Gazette of the United States Patent & Trademark Office Patents 1208(3): 2370, March 17, 1998

Salts of aminoimidazole carboxamide useful in the prevention and treatment of liver diseases. Official Gazette of the United States Patent & Trademark Office Patents 1243(1), Feb 6, 2001

5 =amino or substituted amino 1 2 3 triazoles us patent 4816469 march 28 1989. Official Gazette of the United States Patent & Trademark Office Patents 1100(4): 2426, 1989

5 amino or substituted amino 1 2 3 triazoles useful as antiproliferative agents us patent 4847257 july 11 1989. Official Gazette of the United States Patent & Trademark Office Patents 1104(2): 1245-1246, 1989

Synthesis and antihypertensive activity of 5 substituted 3 amino 4 2 6 dichlorobenzylideneamino 4h 1 2 4 triazoles and the corresponding 3 4 diamino 4h 1 2 4 triazoles. European Journal of Medicinal Chemistry 21(3): 235-244, 1986

1,2,4-triazoles, III: new 1,5-diaryl-3-(substituted amino)-1H-1,2,4-triazoles as anti-inflammatory agents. Archiv der Pharmazie 322(10): 583-587, 1989

2 4 triazoles iii new 1 5 diaryl 3 substituted amino 1h 1 2 4 triazoles as antiinflammatory agents. Archiv der Pharmazie (Weinheim) 322(10): 583-588, 1989

1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10H-pyrimido[1,2-a][1,8]naphthyridine-6-carboxamide derivative. European Journal of Medicinal Chemistry 86: 394-405, 2015

Discovery of 5-substituted pyrrolo[2,3-d]pyrimidine antifolates as dual-acting inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis: implications of inhibiting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase to ampk activation and antitumor activity. Journal of Medicinal Chemistry 56(24): 10016-10032, 2014

A HPLC method for simultaneous determination of 5-aminoimidazole-4-carboxamide riboside and its active metabolite 5-aminoimidazole-4-carboxamide ribotide in tumor-bearing nude mice plasma and its application to pharmacokinetics study. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 915-916: 64-70, 2013

Synthesis of -labelled 4-pyrimidin-4-ylamino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,3-amino-2,. Journal of Labelled Compounds and Radiopharmaceuticals 49(7): 635-640, 2006

Reactivity of 3-aryl-4-amino-5-mercapto-4H-1,2,4-triazoles: synthesis and biological evaluation of 3,6-diaryl derivatives of 7H-1,2,4-thiazole[3,4-b][1,3,4]thiadiazines, of 3-aryl-4-amino-5-carboxymethylthio-4H-1,2,4-triazoles. Il Farmaco; Edizione Scientifica 42(7): 525-539, 1987

Reactivity of 3 aryl 4 amino 5 mercapto 4h 1 2 4 triazoles synthesis and biological evaluation of 3 6 diaryl derivatives of 7h 1 2 4 thiazolo 3 4 b 1 3 4 thiadiazine of 3 aryl 4 amino 5 carboxymethylthio 4h 1 2 4 triazoles. Farmaco Edizione Scientifica 42(7): 525-540, 1987

Quaternary salts of 2 hydroxyiminomethylimidazole 5. structure activity relationships for side chain nitro substituted sulfone substituted amino substituted and aminosulfonyl substituted analogues for therapy against anticholinesterase intoxication. Journal of Medicinal Chemistry 34(4): 1368-1376, 1991